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Application of a Bacillus fermented extract in the prevention and treatment of plant diseases and insect pests

A plant disease and extract technology, which is applied in the fields of application, plant growth regulators, and microbial-based methods, can solve the problems of pest resistance, harm to human health, and pesticide residues, and achieve simple production processes and low toxicity to humans and animals , The effect of low product cost

Active Publication Date: 2019-12-27
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, the beet armyworm often breaks out and becomes a major pest in my country, causing serious losses to agricultural production.
Similar to the control of the above-mentioned plant diseases, the current control of beet armyworm mainly relies on chemically synthesized pesticides, and its long-term use has caused a series of worrying problems, such as: pest resistance, ecological balance damage, and pesticide residues endanger human health Wait

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1: Bacillus horneckiae Preparation of DSM23495 fermentation extract

[0013] (1) Fermentation culture

[0014] According to the conventional culture method of microorganisms, select a small amount of strains stored on the slope of LB solid medium Bacillus horneckiae DSM23495, inoculated on the surface of the LB solid plate, cultured at 30°C for 2 days, as a strain for large-scale fermentation culture, ready for use.

[0015] LB solid medium: 1% tryptone, 0.5% yeast extract, 1% NaCl, 1% agar, distilled water, pH adjusted to 7.0.

[0016] Cut the above-mentioned bacteria on the surface of the LB solid plate, inoculate it into an Erlenmeyer flask of a sterile LB liquid medium, and culture it on a shaker at 30° C. and 120 rpm for 10 days for later use.

[0017] (2) Preparation of fermentation extract

[0018] The above LB liquid medium was extracted 3 times with ethyl acetate, the ethyl acetate extracts were combined and distilled under reduced pressure to obtain an extra...

Embodiment 2

[0019] Example 2: Antibacterial activity test

[0020] Using micro-dilution method to determine Bacillus horneckiae The antibacterial activity of the fermentation extract of DSM23495 against Botrytis cinerea, Fusarium wilt and apple rot disease.

[0021] 1) Preparation of bacterial suspension

[0022] After inoculating the test fungus on the surface of the PDA medium and culturing for 72 h at 28°C, draw 2 mL of sterile 0.85% NaCl solution (containing 0.25% Tween-20) to wash the culture, and gently scrape the colony with a glass spatula. Pipette an appropriate amount of bacterial suspension into a sterile test tube and adjust it to 0.5 McDonald's turbidity (equivalent to 1.5×10 8 CFU / mL) spare.

[0023] 2) Sample preparation

[0024] Take a certain amount of the sample to be tested (the elution component I prepared in Example 1), dissolve it in 100 μL of 50% DMSO, mix well, pipette 50 μL of the sample solution into another centrifuge tube, and then add 50 μL 50% DMSO to obtain a samp...

Embodiment 3

[0031] Example 3: Determination of insecticidal activity of Spodoptera exigua

[0032] Determined by leaf disc dipping method Bacillus horneckiae The insecticidal activity of the fermented extract of DSM23495 against the 3rd instar larvae of Spodoptera exigua.

[0033] Operation steps: (1) Cut the mesophyll of fresh cabbage leaves into small leaf discs of 1 cm × 1 cm, and prepare the sample (elution fraction II prepared in Example 1) with a 90% acetone solution to make a solution of a certain concentration; (2) Take 50 μL of sample solution and add it to a 24-well plate with 4 leaf discs, 8 replicates for each concentration, with 90% acetone solution as a blank control; (3) After the solvent evaporates, add Spodoptera exigua 3 Instar larvae, 1 per hole, covered with a lid, cultured in the dark at 35°C and RH40%; (4) After culturing for 48 hours, observe the feeding and death of the beet armyworm larvae, and calculate the corrected mortality and suppressed feeding rate . Correcte...

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PUM

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Abstract

The invention discloses applications of bacillus horneckinae DSM23495 fermentation extract in preventing and treating plant diseases and spodoptera exigua hubner, belonging to the field of microbial pesticides. The strain is preserved in the China General Microbiological Culture Collection Center (CGMCC), and is assigned with the accession number of CGMCC No.13551. The bacillus horneckinae DSM23495 fermentation extract is obtained through shaking table fermentation adopting a culture medium, extraction of ethyl acetate, and chromatography of a silica gel column, has relatively good inhibitingactivity for the plant diseases including botrytis cinerea, cotton fusarium wilt, valsa mali and alternaria oleracea, and has the minimal inhibiting concentrations (MIC) being 4 [mu] g / mL, 8 [mu] g / mL, 8 [mu] g / mL and 10 [mu] g / mL; in addition, the bacillus horneckinae DSM23495 fermentation extract has relatively good insecticidal activity for spodoptera exigua hubner, and the feeding inhibiting rate achieves 86.1+ / -2.2 % when the concentration is 0.4mg / mL. Therefore, the bacillus horneckinae DSM23495 fermentation extract can be used for preparing the microbial pesticides for preventing and treating plant diseases and spodoptera exigua hubner, compared with the chemically synthesized pesticides, the bacillus horneckinae DSM23495 fermentation extract has the advantages that drug resistanceis seldom generated, the environment compatibility is good, and thus the bacillus horneckinae DSM23495 fermentation extract has good application prospects.

Description

Technical field [0001] The invention belongs to the field of biological pesticides, specifically Bacillus horneckiae The application of DSM23495 fermented extract in the control of plant diseases and beet armyworm. Background technique [0002] Apples, tomatoes and cotton are the main economic crops in my country, especially Jiaodong apples are well-known throughout the country, bringing huge economic benefits to the local area. In recent years, with the extensive use of chemically synthesized pesticides, the above-mentioned crop diseases have become more resistant to pesticides, causing direct economic losses of 20-70%. This also brings problems such as excessive pesticide residues, environmental pollution and even human and animal poisoning. [0003] Beet Armyworm ( Spodoptera exigua Hübner) belongs to the family Lepidoptera Noctuidae. It is an omnivorous pest with a worldwide distribution and intermittent occurrence. It occurs in the economic crop production areas in both sou...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A01N63/02A01P3/00A01P7/04C12R1/07
Inventor 杜丰玉肖琳周远明牛赡光居广琳
Owner QINGDAO AGRI UNIV