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A traditional Chinese medicine composition for clearing heat, promoting dampness, removing blood stasis and stopping belt, its preparation process and application

A technology for clearing away heat and removing dampness and a composition, applied in the directions of drug combinations, antipyretics, pharmaceutical formulations, etc., can solve problems such as troublesome production and lack, and achieve the effects of decreasing viscosity, facilitating disintegration, and weakening the dense network structure.

Active Publication Date: 2021-02-02
江西心正药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are too many types of excipients used in tablets, which is troublesome to make and lacks substances with more comprehensive functions

Method used

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  • A traditional Chinese medicine composition for clearing heat, promoting dampness, removing blood stasis and stopping belt, its preparation process and application

Examples

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Effect test

preparation example Construction

[0026] Preparation of Guangdong Purple Pearl Dry Extract

[0027] Take Guangdong purple pearl, moisten thoroughly, cut into small pieces or original slices, add water and decoct twice, the first time for 3 hours, the second time for 2 hours, combine the decoction, filter, concentrate the filtrate to a thick paste, and dry under reduced pressure , to obtain Guangdong Purple Pearl Dry Extract. Each 1g of dry extract is equivalent to 33.0g of the original medicinal material.

[0028] Preparation of Motherwort Dried Extract

[0029] Take motherwort, chop it, add water to decoct twice, each time for 2 hours, combine the decoction, and filter. The filtrate is concentrated into a thick paste and dried under reduced pressure to obtain the dry extract of Motherwort. Each 1g of dry extract is equivalent to 14.0g of the original medicinal material.

[0030] Preparation of dried extract of black yao yao

[0031] Slice the black medicine, add water and decoct twice, 2 hours each time,...

Embodiment 1

[0035]The preparation method of the traditional Chinese medicine composition tablet for clearing away heat, promoting dampness, removing blood stasis and stopping belt comprises the following steps: 1) Ingredients: weigh 167g of Guangdong Zizhu dry extract, 44g of motherwort dry extract, 39g of Wuyao dry extract, Liushenqu polysaccharide 15g; crush the raw materials through a 60-mesh sieve, add 40g of microcrystalline cellulose, and mix evenly to obtain a mixture. 2) Granulation: add 60% ethanol water solution to the above mixture as a wetting agent, make soft materials, sieve to obtain wet granules, dry, granulate, and obtain dry granules; 3) Compression: compress dry granules 4) Coating: Put the plain tablets in the coating pot, start the coating machine, turn on the heating, spray evenly on the surface of the plain tablets with 10% corn protein ethanol solution, the solvent is heated and volatilized, and the coating is finished. The material forms an isolation layer on the ...

Embodiment 2

[0037] The preparation method of the traditional Chinese medicine composition tablet for clearing away heat, promoting dampness, removing blood stasis and stopping belt comprises the following steps: 1) Ingredients: weigh 167g of Guangdong Zizhu dry extract, 44g of motherwort dry extract, 39g of Wuyao dry extract, Liushenqu polysaccharide 8g; crush the raw materials through a 60-mesh sieve, add 60g of pregelatinized starch, and mix evenly to obtain a mixture. 2) Granulation: add 70% ethanol water solution to the above mixture as a wetting agent, make soft materials, sieve to obtain wet granules, dry, granulate, and obtain dry granules; 3) Compression: compress dry granules 4) Coating: Put the plain tablets in the coating pot, start the coating machine, turn on the heating, spray evenly on the surface of the plain tablets with 15% ethanol solution of shellac, the solvent is heated and volatilized, and the coating is finished. The material forms an isolation layer on the surface...

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Abstract

The invention relates to a traditional Chinese medicine composition for clearing heat, promoting dampness, removing blood stasis and stopping lesion, as well as its preparation process and application. In parts by mass of raw materials, the traditional Chinese medicine composition includes 167 parts of Guangdong Zizhu dry extract, 44 parts of motherwort dry extract, 39 parts of black medicine dry extract, and 5-20 parts of Liushenqu polysaccharide. Compared with the prior art, the present invention adds the extract of Divine Comedy to the existing prescription. The Divine Comedy can invigorate the spleen, regulate qi, and remove dampness, which is beneficial to gynecological inflammation caused by water-damp accumulation; , can be complexed with metal ions to inhibit its catalytic oxidation; at the same time, Liushenqu polysaccharide has good viscosity, and can be granulated well without adding binders when making tablets. After entering the gastrointestinal tract, contact with gastric acid, weaken the dense network structure, significantly reduce the viscosity, and facilitate the disintegration of the tablet, without disintegrants, so that the drug can be dissolved quickly.

Description

technical field [0001] The invention belongs to the technical field of medicine preparation, and relates to a traditional Chinese medicine composition for clearing away heat, promoting dampness, removing blood stasis and stopping belt, as well as its preparation process and application. Background technique [0002] At present, the incidence of gynecological inflammatory diseases in my country is relatively high, and there is a large demand for drugs for the treatment of gynecological inflammation. At the same time, with the development of social economy and culture and the enhancement of women's self-care awareness, gynecological inflammation drugs have grown rapidly in recent years, and the market structure of gynecological inflammation drugs has also undergone great changes. Many gynecological inflammations are mainly caused by the invasion of the Chong, Ren, and Dai pulses by damp-heat evils, resulting in the failure of the band pulses and the imbalance of Chong and Ren....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/85A61K47/36A61P15/00A61P29/00A61K31/715
Inventor 谢亮周伟祥
Owner 江西心正药业有限责任公司
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