Slow-release cutaneous penetration patch used for vulva seborrheic dermatitis

A technology for vulvar fat and dermatitis, applied in skin diseases, drug combinations, pharmaceutical formulations, etc., can solve the problems of ulcer surface enlargement, toxic side effects, deepening and other problems, and achieve the effect of good curative effect

Inactive Publication Date: 2018-02-02
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the medicines for external use are mixed with 5% sulfur cream and glucocorticoid cream for external application. Although they have good efficacy, these medicines have certain toxic and side effects. treatment effect

Method used

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  • Slow-release cutaneous penetration patch used for vulva seborrheic dermatitis
  • Slow-release cutaneous penetration patch used for vulva seborrheic dermatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0073] 20-30 parts of amaranthus, 20-30 parts of gymnasium vine, 20-30 parts of small tree leaves, 15-30 parts of sedge,

[0074] 15 to 30 parts of scorpion vine, 10 to 30 parts of Dongfeng grass, 10 to 25 parts of Kochia scoparia, 10 to 25 parts of white moss bark,

[0075] 10-20 parts of suet, 10-20 parts of snake grape root, 9-15 parts of licorice, 9-15 parts of sea pine nuts,

[0076] 6-15 parts of Asparagus, 6-15 parts of Sophora japonica, 6-12 parts of Witch Root, 6-12 parts of Red Heliotrope,

[0077] 6-12 parts of wild pepper leaves, 4-10 parts of Fructus Lily, 4-10 parts of linseed, 3-9 parts of cnidium,

[0078] 3-9 parts of Jade Butterfly, 3-6 parts of Osmanthus fern, 3-6 parts of Ling Xiaohua, and 1-3 parts of borneol.

[0079] The processing steps of the pharmaceutical preparation method of the present invention are:

[0080] (1) Combine amaranth...

Embodiment 2

[0094] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0095] 25-30 parts of amaranthus, 25-30 parts of gymnasium vine, 20-26 parts of small tree leaves, 18-25 parts of sedge,

[0096] 18 to 25 parts of scorpion vine, 15 to 25 parts of Dongfeng grass, 12 to 20 parts of Kochia scoparia, 12 to 20 parts of white moss bark,

[0097] 12-18 parts of suet, 12-18 parts of snake grape root, 12-15 parts of licorice, 10-13 parts of sea pine nuts,

[0098] 8-13 parts of Asparagus, 8-12 parts of Sophora japonica, 8-10 parts of Heliconia root, 8-10 parts of Red Heliotrope,

[0099] 6-10 parts of wild pepper leaves, 6-9 parts of Sapphire, 5-8 parts of linseed, 5-8 parts of cnidium,

[0100] 5-7 parts of Jade Butterfly, 4-6 parts of Osmanthus fern, 3-5 parts of Ling Xiaohua, and 1-2 parts of borneol.

[0101] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example...

Embodiment 3

[0103] The raw material composition and the weight of active ingredient of medicine of the present invention are:

[0104] 28 parts of Amaranth, 28 parts of gymnasium vine, 24 parts of small tree leaves, 22 parts of sedge,

[0105] 22 parts of scorpion vine, 20 parts of Dongfeng grass, 18 parts of Kochia scoparia, 16 parts of white moss bark,

[0106] 16 parts of suet, 15 parts of snake grape root, 13 parts of licorice, 12 parts of sea pine nuts,

[0107] 10 parts of Asparagus, 10 parts of Sophora japonica, 9 parts of Wingwort root, 9 parts of Red Tiankui,

[0108] 8 parts of wild pepper leaves, 7 parts of Sapphire, 7 parts of linseed, 6 parts of cnidium,

[0109] 6 parts of Jade Butterfly, 5 parts of Lemongrass Fern, 4 parts of Lingxiaohua, and 1 part of Borneol.

[0110] The process steps, usage and dosage of the medicine preparation method in this embodiment are the same as those in Example 1.

[0111] clinical information:

[0112] 1. Case selection

[0113] 80 patie...

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PUM

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Abstract

The invention discloses a slow-release cutaneous penetration patch used for vulva seborrheic dermatitis, and belongs to the field of traditional Chinese medicine. The effective components of the drugare composed of alternanthera phioxeroides, gymnema sylvestre, broussonetia kaempferi sieb leaves, nutgrass flatsedge, Chinese starjasmine stems, blumea megacephala, fructus kochiae, dittany bark, mutton tallow, ampelopsisroots, licorice roots, Korean pine seeds, asparagus cochinchinensis, Japanese pagodatree bark, polygonum orientale roots, tea begonia, flatspine pricklyash leaves, climbing figs,linseeds, fructus cnidii, semen oroxyli, mecodium microsorum, Chinese trumpet creepers and borneol. The selected medicinal materials conform to the principle of assistance and guidance and suit the remedy to the case aiming at disease causes, the slow-release cutaneous penetration patch has the functions of cooling blood and clearing heat, resolving toxin and dispersing swelling, dispelling windand arresting itching, eliminating dampness and dredging channels, nourishing yin for moistening dryness, healing up sore and promoting granulation and moistening the skin, is good in absorption effect and obvious in curative effect, has no toxic and side effect and clinical adverse reaction, and through clinical verification, the recovery rate of vulva seborrheic dermatitis is high.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a sustained-release transdermal drug delivery patch for seborrheic dermatitis of the vulva. Background technique [0002] Vulvar seborrheic dermatitis is a superficial, chronic inflammatory skin disease that occurs on the basis of seborrhea, usually starting from the head and spreading downward to other parts rich in sebaceous glands, manifested as dark red or yellow-red patches Covered with greasy scales or crusts, with varying degrees of itching. The etiology of this disease is not completely clear so far, but at present, it is generally believed that the disease may be related to the increase in the activity of the sebaceous glands, resulting in an increase in the release of sebum or changes in related chemical components, resulting in imbalance of the skin surface flora, and secondary microbial infections: such as Pityrosporum ovale and Brevibacterium acnes proli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61K9/70A61K9/06A61P17/08A61P17/00A61M37/00A61K31/045A61K35/35
CPCA61K9/06A61K9/7084A61K31/045A61K35/35A61K36/12A61K36/15A61K36/185A61K36/21A61K36/234A61K36/24A61K36/27A61K36/41A61K36/484A61K36/489A61K36/55A61K36/60A61K36/704A61K36/75A61K36/758A61K36/81A61K36/87A61K36/8905A61K36/8965A61K2236/331A61K2236/333A61K2236/39A61M37/00A61M2037/0007A61K2300/00
Inventor 郁博吕雅琳周璐王宗岭苏磊
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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