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Preparation for treating hemophilia and von willebrand disease caused by heat stagnation blood aspect and method

A hemophilia and vascular technology, applied in medical preparations containing active ingredients, blood diseases, pharmaceutical formulations, etc., can solve the problems of lack of pertinence, unsatisfactory effects, and side effects of drugs, and improve bioavailability. , Helps to improve the absorption and dissolution rate

Inactive Publication Date: 2018-02-09
天津市善济宏兴科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many types of drugs currently used clinically to treat hemophilia and von Willebrand disease, there are many factors that cause hemophilia and von Willebrand disease, and hemophilia and von Willebrand disease There are also many types of hemophilia, so these drugs lack specificity, the course of treatment is relatively long, and some drugs have certain side effects or allergic reactions, so after taking it, it is very useful for the treatment of hemophilia and vascular pseudosomnia caused by heat stagnation. Not ideal for a disease like hemophilia

Method used

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  • Preparation for treating hemophilia and von willebrand disease caused by heat stagnation blood aspect and method
  • Preparation for treating hemophilia and von willebrand disease caused by heat stagnation blood aspect and method
  • Preparation for treating hemophilia and von willebrand disease caused by heat stagnation blood aspect and method

Examples

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Effect test

Embodiment 1

[0016] The traditional Chinese medicine compound preparation used in this embodiment for the treatment of hemophilia and von Willebrand's disease caused by stagnation of heat is made from the following pharmaceutical raw materials in terms of weight ratio:

[0017] Stir-fried gardenia 6 Peony bark 6 Raw rhubarb 6 Imperata rhizome 18 Cucumber 6

[0018] Large thistle 6 Small thistle 6 Madder 9 Agrimony 18 Arborvitae leaf 6

[0019] Nepeta Charcoal 6 Raw Licorice 4

[0020] The preparation method of the Chinese medicine compound preparation for treating hemophilia and von Willebrand's disease caused by heat stagnation is carried out according to the following steps:

[0021] (a) weighing and mixing other medicinal raw materials except raw rhubarb in the above medicinal raw materials according to the proportion, then soaking in water for 25 minutes, and then decocting;

[0022] (b) When the herbal medicines in step (a) are decocted for 25 minutes, add raw rhubarb, continue to d...

Embodiment 2

[0025] The traditional Chinese medicine compound preparation used in this embodiment for the treatment of hemophilia and von Willebrand's disease caused by stagnation of heat is made from the following pharmaceutical raw materials in terms of weight ratio:

[0026] Stir-fried Gardenia 15 Peony Bark 15 Raw Rhubarb 15 Imperata Rhizome 48 Cucumber 15

[0027] Large thistle 15 Small thistle 15 Madder 24 Agrimony 48 Arborvitae leaves 15

[0028] Nepeta Charcoal 15 Raw Licorice 10

[0029] The preparation method is the same as in Example 1.

Embodiment 3

[0031] The traditional Chinese medicine compound preparation used in this embodiment for the treatment of hemophilia and von Willebrand's disease caused by stagnation of heat is made from the following pharmaceutical raw materials in terms of weight ratio:

[0032] Stir-fried gardenia 8 Peony bark 8 Raw rhubarb 8 Imperata root 25 Cucumber 8

[0033] Large thistle 8 Small thistle 8 Madder 12 Agrimony 25 Arborvitae leaves 8

[0034] Nepeta Charcoal 8 Raw Licorice 5

[0035] The preparation method is the same as in Example 1.

[0036] The traditional Chinese medicine compound preparation for treating hemophilia and von Willebrand's disease caused by heat stagnation provided by the invention is brown to brown in color, light in breath and slightly bitter in taste. In order to verify the therapeutic effect of this Chinese medicine compound preparation, the inventor has carried out a systematic clinical observation on 285 patients with heat stagnation blood type hemophilia and von...

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Abstract

The invention relates to a preparation for treating hemophilia and von willebrand disease caused by heat stagnation blood aspect and a method. The preparation is made of, by weight ratio, 6-15% of stir-fried cape jasmine fruit, 6-15% of tree peony bark, 6-15% of raw rhubarb, 18-48% of lalang grass rhizome, 6-15% of polygonum aviculare, 6-15% of Japanese thistle herb or root, 6-15% of common cephalanoplos herb, 9-24% of radix rubiae, 18-48% of hairyvein agrimonia herb and bud, 6-15 parts of Chinese arborvitae twig, 6-15% of carbonized catnip and 4-10% of radix glycyrrhizae. According to the preparation, a boiling extraction method is adopted to extract active ingredients in the raw medicines and keep activities thereof, so that not only can the dissolution rate of the active ingredients inthe medicines be improved, but also the absorption to the medicines can be facilitated, thereby improving the biological utilization degree thereof. In addition, the medicine is a pure traditional Chinese medicine compound preparation, so a patient does not produce toxic and side effects after long-term use, and the safety is good. In addition, the preparation method has a simple process and is convenient to operate.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine compound preparation made from traditional Chinese medicine for treating hemophilia and von Willebrand disease caused by blood stagnation due to heat stagnation and its preparation method. Background technique [0002] Hemophilia is an inherited bleeding disorder. Its common features are active thrombin generation disorder, long coagulation time, and patients can suffer from severe bleeding even with mild trauma. Von Willebrand's disease is a bleeding disorder characterized by prolonged bleeding time, plasma antihemophilic globulin deficiency, and decreased platelet adhesion. Although there are many types of drugs currently used clinically to treat hemophilia and von Willebrand disease, there are many factors that cause hemophilia and von Willebrand disease, and hemophilia and von Willebrand dis...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P7/04
CPCA61K36/14A61K36/28A61K36/484A61K36/538A61K36/65A61K36/704A61K36/708A61K36/71A61K36/73A61K36/74A61K36/744A61K36/899A61K2236/331A61K2300/00
Inventor 马力王维蔚齐燕松
Owner 天津市善济宏兴科技发展有限公司
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