Chroogomphus rutilus extract and application in anti-diabetic medicine
The technology of extract and nail mushroom, which is applied in the field of drug preparation, can solve the problems such as unreported literature related to anti-diabetic activity, and achieve the effects of clarifying anti-diabetic activity, inhibiting α-glucosidase activity, and hypoglycemic and lipid-lowering effects.
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Embodiment 1
[0031] The preparation of embodiment 1 color nail mushroom ethanol extract
[0032] Carefully select the fruiting body of the sarcophagus, remove the sundries, and dry in an oven. At this time, special attention should be paid to the temperature of the oven, and the temperature of the oven should be controlled at about 40°C. After drying for 24 hours, crush it with a grinder to obtain a dry powder, and weigh it That's it. The dry powder was extracted with 95% ethanol. At this time, the dry powder ethanol ratio should be controlled between Coprinus comatus dry powder: 95% ethanol = 1:6-1:10, after stirring for 4 hours, let stand overnight. The next day, the extract was filtered with suction, and then subjected to vacuum distillation on a rotary evaporator, controlled below 45°C, and the extract was collected. In order to improve the extract yield, the above-mentioned process is circulated 3-5 times. The product is dried in a vacuum drying oven at a temperature lower than 40°...
Embodiment 2
[0033] The preparation of embodiment 2 color nail mushroom petroleum ether extracts
[0034] Mix the ethanol extract or the dry powder of the fruiting body of the mantle mushroom with petroleum ether in the ratio of mass volume ratio (0.1~1): 20 (g / mL), stir the extract to suspend it evenly, after stirring for 2 hours, let it stand overnight. The extract was filtered with suction, and then subjected to vacuum distillation on a rotary evaporator, controlled below 45°C, and the extract was collected. In order to improve the extract yield, the above-mentioned process is circulated 3-5 times. The product is dried in a vacuum drying oven at a temperature lower than 40° C. to obtain the petroleum ether extract of the mushroom.
Embodiment 3
[0035] The preparation of embodiment 3 color nail mushroom ethyl acetate extract
[0036] Mix the dry powder of the fruiting body of Semen mangulata with ethyl acetate in the ratio of mass volume ratio (0.1-1): 20 (g / mL), stir the extract to suspend it evenly, after stirring for 2 hours, let it stand overnight. The extract was filtered with suction, and then subjected to vacuum distillation on a rotary evaporator, controlled below 45°C, and the extract was collected. In order to improve the extract yield, the above-mentioned process is circulated 3-5 times. The product is dried in a vacuum drying oven at a temperature lower than 40° C. to obtain the ethyl acetate extract of Semantle mushroom.
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