A drug-loaded aqueous emulsion containing modified polymannuronic acid derivatives and its preparation method

A technology of polymannuronic acid and its derivatives, applied in botany equipment and methods, biocides, animal repellants, etc., can solve the problems of large dosage, large residue, short duration, etc., to improve growth Effects of adaptability, drought resistance improvement, and property stability
CN107964051BActive Publication Date: 2020-09-01HAINAN UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
HAINAN UNIV
Publication Date
2020-09-01

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Abstract

The invention relates to the field of biopolymer materials and particularly relates to a modified polymannuronic acid derivative, a drug-carrying aqueous emulsion and a preparation method thereof. Low-molecular-weight polymannuronic acid as a raw material undergoes an Ugi reaction to produce an amphiphilic polymannuronic acid derivative. The surface activity test result shows that the derivative has a low critical aggregation concentration and good surface activity, can be used as a water emulsion stability aid and has a good regulation effect on the stability and drug release of the emulsion.
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Description

technical field

[0001] The invention relates to the field of biopolymer materials, in particular to a modified polymannuronic acid derivative, its drug-loaded aqueous emulsion and a preparation method. Background technique

[0002] Polymannuronic acid (PM) is widely used in the field of medicine. It has the functions of detoxification, anti-inflammation, anti-coagulation, regulation of immune function and promotion of plant growth. At the same time, it also has good application prospects in the field of agriculture, such as: promoting plant growth, enhancing plant drought resistance, and serving as a slow-release carrier for pesticides. Yang et al. (Yang et al., 2012) prepared amphiphilic sodium alginate derivatives by modifying sodium alginate with dodecyl, and studied the effect of its content on the stability of aqueous emulsion. Modified alginic acid The higher the sodium concentration, the better the stability of the emulsion.

[0003] Today, in the field of agricultu...

Claims

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