Preparation method and product of hydrogel plaster for cold compress

Abstract

The invention discloses a preparation method and a product of a hydrogel plaster for cold compress. The method comprises the following steps: (1) performing an esterifying reaction on polyethylene glycol, polyvinyl alcohol and acrylic acid in the presence of an esterification catalyst to obtain polyethylene glycol and polyvinyl alcohol mixed acrylate; (2) mixing the polyethylene glycol and polyvinyl alcohol mixed acrylate with water-based tackifying resin, a crosslinking agent, a photoinitiator, a humectant, a mildew inhibitor, a cooling agent and water to obtain a hydrogel plaster stock solution for cold compress; and (3) continuously coating a substrate with the hydrogel plaster stock solution for cold compress through a coater, performing ultraviolet illumination to cure the gel, and cutting and packaging the cured gel to obtain the hydrogel plaster product. The preparation method of the hydrogel plaster has the advantages of convenient sources of raw materials, simple production process, rapidness and completeness in gel curing, and suitableness for mass production, and the obtained product has the advantages of stability in storage, no bubbles, high transparency, obvious cooling effect, good applicability and good moisture retention property.

Description

technical field [0001] The invention belongs to the field of making hydrogel patches for medical sporting goods, and in particular relates to a preparation method of hydrogel patches for cold compresses. Background technique [0002] Hydrogel patch, also known as modern cataplasm, is mainly composed of hydrophilic resin, cross-linking agent, moisturizing agent, purified water, functional additives and water-swellable cross-linked polymer and other components. It is mainly used for external gel patches, and is most suitable for cold compresses and external applications on wounds. [0003] Traditional cataplasms first originated in Japan. At first it was kaolin cataplasm. Its production method is generally to mix cereals such as oatmeal with water, milk, wax, etc., and then mix them with medicine to make a mud-like substance, and put it into an airtight container. In use, it is applied on gauze and pasted on the affected area, which is called mud-like poultice (clay). This p...

AI Technical Summary

Problems solved by technology

[0007] However, in the preparation process of existing hydrogel stickers, most of the skeleton materials are formed by chemical crosslinking of water-soluble polymers added with crosslinking agents (for example, the publication number is CN 102614517A patent document). Because the crosslinking reaction speed is difficult to control, the skeleton materials The main structure of the hydrogel is rapidly formed in a short period of time, resulting in a rapid and substantial increase in the viscosity of the system, which brings great difficulties to the coating and sizing process of the hydrogel paste, resulting in uneven coating, multiple bubbles, and dispersion of functional additives in the product It is not easy to wait for a series of defects, and it is difficult to complete the complete cross-linking reaction of the hydrogel skeleton material in a short time. Cutting and packaging the adhesive sticker too early will lead to the breakage and adhesion of the hydrogel, which will lead to the failure of the product. mass production is very difficult

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