Compound polysaccharide with functions of clearing heat, nourishing yin and reducing blood sugar, preparation method and application thereof

A compound polysaccharide and hypoglycemic technology, which is applied in the field of medicine and health care products, can solve the problem of insignificant hypoglycemic effect, achieve the effect of clearing away heat and nourishing yin, lowering blood sugar, and regulating immune function

Inactive Publication Date: 2018-06-15
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are auxiliary hypoglycemic health products developed by using the compatibi

Method used

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  • Compound polysaccharide with functions of clearing heat, nourishing yin and reducing blood sugar, preparation method and application thereof
  • Compound polysaccharide with functions of clearing heat, nourishing yin and reducing blood sugar, preparation method and application thereof
  • Compound polysaccharide with functions of clearing heat, nourishing yin and reducing blood sugar, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: the preparation of reed rhizome polysaccharide

[0032] Weigh an appropriate amount of reed rhizome, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, decoct for 1 hour again, filter, and combine the filtrate twice; concentrate the filtrate to contain 100g of reed rhizome crude drug per 100mL, Add 95% ethanol to 80% ethanol volume, let stand overnight, centrifuge to obtain supernatant and precipitate, freeze-dry the precipitate or dry it at 70°C, and pulverize to obtain reed rhizome polysaccharide.

Embodiment 2

[0033] Embodiment 2: the preparation of the polysaccharide of Rhizoma Imperatae

[0034] Weigh an appropriate amount of Imperata rhizome, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, decoct for 1 hour again, filter, and combine the filtrates twice; concentrate the filtrate to contain 100g of Imperata rhizome crude drug per 100mL, Add 95% ethanol to 80% ethanol volume, let stand overnight, centrifuge to obtain supernatant and precipitate, freeze-dry or dry the precipitate at 70°C, and pulverize to obtain the polysaccharide of Rhizoma Imperatae.

Embodiment 3

[0035] Embodiment 3: the preparation of aspartame polysaccharide

[0036] Weigh an appropriate amount of asparagus, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, decoct for 1 hour again, filter, and combine the filtrate twice; concentrate the filtrate to contain 100g of asparagus crude drug per 100mL, Add 95% ethanol to 80% ethanol volume, let it stand overnight, centrifuge to obtain supernatant and precipitate, freeze-dry the precipitate or dry it at 70°C, and pulverize to obtain aspartame polysaccharide.

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Abstract

The invention belongs to the field of medicine and health care products, and specifically discloses a compound polysaccharide, a preparation thereof and application thereof in products with the functions of clearing heat, nourishing yin and reducing blood sugar. The compound polysaccharide is prepared from rhizoma phragmitis, lalang grass rhizome, asparagus fern, Radix Ophiopogonis and folium eriobotryae. The preparation method comprises water extraction and alcohol precipitation. According to the compound polysaccharide, the food intake, water intake and urine volume of an internal heating yin deficiency type hyperglycemia rat model can be obviously reduced, and the weight of the rat is increased; the content of insulin is reduced, and the resistance to insulin is improved; triglyceride and total cholesterol are reduced, and the symptom of hyperlipidemia is improved; the immunity indexes, such as cAMP and cGMP, are reduced, and the abnormal phenomena of immunity is improved; the appearance state and spiritual attitude of internal heating yin deficiency rats are improved, the effect is obviously superior to single polysaccharide ingredients, and the compound polysaccharide can be used for preparing medicine or health food with the effects of clearing heat, nourishing yin and reducing blood sugar.

Description

technical field [0001] The invention belongs to the field of medicines and health care products, and in particular relates to a compound polysaccharide and its preparation method and application, especially a compound polysaccharide with functions of clearing heat, nourishing yin and lowering blood sugar, and its preparation method and application. Background technique [0002] Hyperglycemia is when blood sugar levels are higher than the normal range. Under normal circumstances, the human body can ensure the balance between the source and outlet of blood sugar through the two major regulatory systems of hormone regulation and nerve regulation, so that blood sugar can be maintained at a certain level. However, under the joint action of genetic factors (such as family history of diabetes) and environmental factors (such as unreasonable diet, obesity, etc.), the two major regulatory functions are disturbed, and blood sugar levels will rise. Short-term, one-time hyperglycemia h...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K31/715A61P3/10A23L33/105
CPCA23V2002/00A61K31/715A61K36/73A61K36/8965A61K36/8968A61K36/899A23L33/105A61K2300/00A23V2200/328A23V2250/21
Inventor 胡明华徐路尹西拳从仁怀马方励
Owner INFINITUS (CHINA) CO LTD
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