HPLC detection method of neomycin sulfate component in Qumixin cream

A neomycin sulfate and detection method technology, applied in the field of chemical detection, can solve the problems of time-consuming and labor-intensive neomycin sulfate, uncontrolled neomycin sulfate content, etc., and achieve the effect of stable detection method, small error and high detection efficiency
CN108303483BActive Publication Date: 2021-06-01GUANGDONG SHUNFENG PHARMA

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
GUANGDONG SHUNFENG PHARMA
Publication Date
2021-06-01

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Abstract

The invention belongs to the field of chemical detection, and in particular relates to an HPLC detection method for the neomycin sulfate component in Qumixin cream, including (1) chromatographic conditions and system applicability test (2) solution preparation (3) determination and other steps . The HPLC detection method of the neomycin sulfate component in Qumixin emulsifiable cream of the present invention has the advantages of simple operation, high detection efficiency, small error, strong specificity, relatively stable detection method, less affected factors, and wide applicability ; The accuracy, precision, specificity, detection limit, etc. of the method all meet the methodological verification requirements, and have strong practicability. The method is used to analyze the neomycin sulfate group in the Trimixin cream produced by various enterprises. The detection can be carried out separately, and the content of each component of neomycin sulfate can be detected quickly and accurately, which is beneficial to the determination of the samples of Trimethin cream produced by various enterprises.
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Description

technical field

[0001] The invention belongs to the field of chemical detection, and in particular relates to an HPLC detection method for the neomycin sulfate component in Qumixin cream. Background technique

[0002] Qumixin Cream is a compound preparation for external use on the skin, which has a strong antifungal effect. There are athlete's foot net cream and Pikang cream. Qumixin Cream is a non-essential drug independently developed by my country. It was first developed and produced by Guangdong China Resources Shunfeng Pharmaceutical Co., Ltd. and was approved for sale in 1985. Due to its remarkable therapeutic effect, it has been widely used clinically at present, and its main components are: miconazole nitrate, triamcinolone acetonide acetate and neomycin sulfate.

[0003] Neomycin sulfate (Neomycin sulfate) is one of the main components of Quamixin cream. It is a multi-component aminoglycoside antibiotic. It has a good antibacterial effect on Staphylococcus and Cor...

Claims

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