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oral care composition

A technology for oral care and composition, which is applied in the field of oral care compositions and can solve the problems of high delivery of gain agents and other problems

Active Publication Date: 2021-08-24
UNILEVER IP HLDG BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, achieving high delivery of benefit agents from oral care compositions is often difficult

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] This example demonstrates improved deposition of particles on tooth surfaces by using calcium silicate in combination with xanthan gum. All ingredients are expressed as percentages by weight of the total formulation and expressed as active ingredient levels.

[0127] Table 1

[0128]

[0129] a. by trade name S-97BF is a commercially available PVM / MA copolymer from Ashland

[0130] b. Commercially available sodium alginate from Sinopharm Group Co.Ltd

[0131] c. by trade name Xanthan Gum Commercially available xanthan gum from CP Kelco

[0132] d. by trade name Carrageenan CL110 Commercially available carrageenan from Danisco

[0133] e. Commercially available copolymer of acrylamide and sodium acrylamido tert-butyl sulfonate available from SNF under the tradename Flopaam AN125

[0134] f. Under the trade name EPITEX TM 66 commercially available acrylate copolymers from Dow Chemical Company

[0135] g. Commercially available calcium silicate coated tit...

Embodiment 2

[0154] This example demonstrates the effect of particle concentration on particle deposition efficiency. All ingredients are expressed as weight percent of the total formulation and expressed as active ingredient content.

[0155] Table 6

[0156]

[0157] method

[0158] As described in Example 1, the same protocol was used to evaluate the deposition of particles on tooth surfaces.

[0159] result

[0160] Results after one and three treatment cycles are summarized in Table 7 (errors represent standard errors of repeated measures).

[0161] Table 7

[0162]

[0163] After one cycle of treatment, with TiO containing 0.5% 2 The HAP disks treated with Sample 10 show almost no titanium deposition, while those treated with samples containing more than 5% TiO 2 The HAP disks treated with Samples 13 and 14 exhibited much higher Ti deposition. Furthermore, Sample 15 containing composite particles exhibited better particle deposition than those containing uncoated TiO...

Embodiment 3

[0165] This example demonstrates the effect of xanthan gum concentration on particle deposition efficiency. All ingredients are expressed as weight percent of the total formulation and expressed as active ingredient content.

[0166] Table 8

[0167]

[0168] method

[0169] As described in Example 1, the same protocol was used to evaluate the deposition of particles on tooth surfaces.

[0170] result

[0171] The results after one processing cycle are summarized in Table 9 (errors represent the standard error of repeated measures).

[0172] Table 9

[0173]

[0174] From the XRF results, it can be seen that the concentration of xanthan gum is important for particle deposition efficiency. Sample 16 without xanthan gum was used as a control. Samples 17 to 19 containing 0.3% or less of xanthan gum showed comparable titanium deposition to sample 16, indicating that small amounts of xanthan gum did not contribute to particle deposition. Compared to Sample 16, Samp...

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Abstract

Disclosed is an oral care composition comprising 5-80% by weight of calcium silicate, 0.4-2% by weight of xanthan gum and / or its derivatives, a benefit agent and a physiologically acceptable carrier, wherein the The benefit agent is selected from the group consisting of coloring agents, biomineralizers, antibacterial agents or mixtures thereof, and wherein said biomineralizer is amorphous calcium phosphate, alpha-tricalcium phosphate, beta-tricalcium phosphate; calcium carbonate, calcium deficient Type hydroxyapatite (Ca 9 (HPO 4 )(PO 4 ) 5 OH), dicalcium phosphate (CaHPO 4 ), dicalcium phosphate dihydrate (CaHPO 4 2H 2 O), hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 ), monocalcium phosphate monohydrate (Ca(H 2 PO 4 ) 2 ·H 2 O), octacalcium phosphate (Ca 8 h 2 (PO 4 ) 6 ·5H 2 O) and tetracalcium phosphate (Ca 4 (PO 4 ) 2 O) or mixtures thereof.

Description

technical field [0001] The present invention relates to oral care compositions such as toothpastes, gums, mouthwashes and the like. In particular, the present invention relates to oral care compositions comprising calcium silicate, a particulate benefit agent and a deposition aid. The present invention also relates to the use of such compositions for benefiting the teeth of an individual. Background technique [0002] Many of the products we consume have negative effects on our teeth and mouth. For example, acidic beverages and sweets can cause tooth erosion by attacking the enamel that protects the outer coating of the teeth. Also, tobacco-based products and beverages such as coffee and tea can stain or reduce the whiteness of teeth. These staining and discoloring substances are often able to penetrate the enamel layer. This problem occurs gradually over many years, but can lead to noticeable discoloration of the tooth enamel. [0003] Consumers have always had a stron...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/73A61K8/25A61K8/29A61K8/24A61Q11/00
CPCA61K8/25A61K8/29A61Q11/00A61K8/73
Inventor 李雅娟唐学智王进防
Owner UNILEVER IP HLDG BV
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