Nitraria tangutorum seed extract

Abstract

The invention provides a nitraria tangutorum seed extract. The nitraria tangutorum seed extract is prepared through the following method comprising the following steps: taking nitraria tangutorum seeds, taking water or an alcohol aqueous solution as a solvent to extract, concentrating an extracting solution until not alcohol taste exists, adopting an petroleum ether-water system to extract, takinga water layer, and removing the solvent to obtain the nitraria tangutorum seed extract. According to the research, the nitraria tangutorum seed extract provided by the invention can reduce total cholesterol, total triglyceride, and low-density lipoprotein cholesterol in a hyperlipidemic rat, increases high-density lipopmtein cholesterol, and can resist abnormal growth of weight of the hyperlipemia rat to certain extent. Meanwhile, through pathological slice observation on the hepatic tissue of each group of rats, the extract can improve changes of adipose tissues and cell shapes of the fattyliver disease to different extents, and provides a novel choice for clinically preventing or treating hyperlipidaemia or the fatty liver diseases. Meanwhile, the nitraria tangutorum seed extract findsa novel active part except from nitraria tangutorum seed oil, and provides a novel direction for development and utilization of nitraria tangutorum seeds.

Description

technical field [0001] The invention relates to a Nitraria japonica seed extract. Background technique [0002] Hyperlipidemia is the main cause of atherosclerosis and related diseases such as coronary heart disease, ischemic brain disease and peripheral vascular disease. Although the incidence of diseases related to atherosclerosis has been improved due to drug treatment and prevention, the above conditions still account for a large proportion of morbidity and mortality in middle-aged and elderly people. Due to the increasing prevalence of obesity and the aging of the world population, the annual incidence and number will increase substantially in the next decade. Dyslipidemia is caused by abnormal blood lipid metabolism, such as the increase of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C) and the decrease of high-density lipoprotein (HDL-C) in serum. In particular, studies have shown that increased LDL-C concentrations play a major role in t...

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Problems solved by technology

[0004] At present, the research on the hypolipidemic effect of Nitraria seeds is only limited to the hypolipidemic effect of Nitraria seed oil, and the research on the hypolipidemic activity of other parts of Nitraria seeds has not been reported.

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