Methods for preparing CuO/rGO@PNIPAm (poly(N-isopropylacrylamide)) electrode and structuring non-enzyme glucose sensor

A glucose sensor, glucose technology, applied in instruments, scientific instruments, material analysis through electromagnetic means, etc., can solve the problems of yield limitation, low synthesis steps, etc., and achieve the degree of easy compounding, low energy consumption, and significant temperature switch effect Effect

Inactive Publication Date: 2018-08-17
NORTHWESTERN POLYTECHNICAL UNIV
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Problems solved by technology

At present, the controllable preparation method of such particles is mainly based on the surface grafting method. Although ...
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Abstract

The invention relates to methods for preparing a CuO/rGO@PNIPAm compound self-support electrode and structuring a thermosensitive non-enzyme glucose sensor and an application method of the thermosensitive non-enzyme glucose sensor. The methods for preparing the CuO/rGO@PNIPAm compound self-support electrode and structuring the thermosensitive non-enzyme glucose sensor comprise preparing a CuO/GO compound membrane from porous CuO and graphene; placing the CuO/GO compound membrane into NIPAM monomer aqueous solution, performing polymerization reaction in an ultrasonic-intermittent/N2 inletting circulating manner to prepare a CuO/GO@PNIPAm compound membrane as a temperature-response flexible electrode; taking the CuO/GO@PNIPAm compound membrane as a self-support working electrode, a saturatedcalomel electrode as a reference electrode and a platinum electrode as an auxiliary electrode to structure the glucose electrochemical sensor. The glucose electrochemical sensor is applied to testingthe state of glucose molecules. The method for preparing the CuO/rGO@PNIPAm compound self-support electrode and structuring the thermosensitive non-enzyme glucose sensor has the outstanding advantages of being high in compounding liability, mild and low in energy consumption. The prepared CuO/rGO@PNIPAm compound self-support flexible electrode can be applied to non-enzyme glucose detection and achieve significant temperature switch effects.

Application Domain

Material analysis by electric/magnetic means

Technology Topic

Cvd grapheneAuxiliary electrode +11

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  • Methods for preparing CuO/rGO@PNIPAm (poly(N-isopropylacrylamide)) electrode and structuring non-enzyme glucose sensor
  • Methods for preparing CuO/rGO@PNIPAm (poly(N-isopropylacrylamide)) electrode and structuring non-enzyme glucose sensor
  • Methods for preparing CuO/rGO@PNIPAm (poly(N-isopropylacrylamide)) electrode and structuring non-enzyme glucose sensor

Examples

  • Experimental program(2)

Example Embodiment

[0026] Example 1:
[0027] a) 5g porous CuO and 5g graphene oxide were prepared into a uniformly dispersed suspension, and a CuO/rGO composite film was prepared by suction filtration with a thickness of 10 μm-30 μm.
[0028] b) Place the CuO/rGO composite film in 1g/L NIPAm monomer aqueous solution, and carry out plug-in reaction by selecting an ultrasonic horn with an ultrasonic frequency of 20kHz, and the ultrasonic power is 200W. The CuO/rGO@PNIPAm composite film was prepared as a temperature-responsive flexible electrode by ultrasonic-intermittent (N2 gas) circulation mode for polymerization reaction and cumulative ultrasonic irradiation for 1 h.
[0029] c) The CuO/rGO@PNIPAm composite film is used as the working electrode, the saturated calomel electrode (SCE) is used as the reference electrode, and the platinum electrode (Pt) is used as the auxiliary electrode. Put the three-electrode system into a weighing bottle filled with 5mM/L glucose NaOH solution, and then put the whole into a water bath. Next, the catalytic performance of CuO/rGO@PNIPAm composites on glucose was studied.

Example Embodiment

[0030] Example 2:
[0031] a) 5g of porous CuO and 10g of graphene oxide were prepared into a uniformly dispersed suspension, and by suction filtration, a CuO/rGO composite film was prepared with a thickness of 10 μm-30 μm.
[0032] b) Place the CuO/rGO composite film in 1g/L NIPAm monomer aqueous solution, and carry out plug-in reaction by selecting an ultrasonic horn with an ultrasonic frequency of 20kHz, and the ultrasonic power is 200W. Ultrasonic-intermittent (pass N 2 The CuO/rGO@PNIPAm composite film was prepared as a temperature-responsive flexible electrode after the polymerization reaction was carried out in the gas) circulation mode, and the cumulative ultrasonic irradiation was 1 h.
[0033] c) The CuO/rGO@PNIPAm composite film is used as the working electrode, the saturated calomel electrode (SCE) is used as the reference electrode, and the platinum electrode (Pt) is used as the auxiliary electrode. Put the three-electrode system into a weighing bottle filled with 5mM/L glucose NaOH solution, and then put the whole into a water bath. Next, the catalytic performance of CuO/rGO@PNIPAm composites on glucose was studied.
[0034] Supplementary Table 1. Comparison of the designed CuO-based glucose sensor with currently reported materials
[0035]
[0036] This patent uses porous CuO and graphene oxide to prepare a uniformly dispersed suspension, and obtains a CuO/rGO composite membrane with a thickness of 10 μm-30 μm by suction filtration. This method is simple and has high sensitivity for glucose detection and a wide linear range. , low detection limit and other advantages.

PUM

PropertyMeasurementUnit
Thickness10.0 ~ 30.0µm
Concentration10.0 ~ 30.0mg/ml

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