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Air-permeable antibacterial silk nano dressing

A kind of silk and nanotechnology, applied in the field of medical materials, can solve the problems of comfort and air permeability that cannot meet the needs of patients, affect the wound repair process, and weak antibacterial ability, and achieve the advantages of promoting wound healing, comfortable use, and good antibacterial properties Effect

Inactive Publication Date: 2018-09-14
SUZHOU BEC BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing medical dressings are generally thick, and the comfort and air permeability cannot meet the needs of patients, which affects the wound repair process
Moreover, current medical dressings also have shortcomings such as weak antibacterial ability and high cost. Therefore, it is extremely important to develop a medical dressing with good comfort, strong antibacterial ability and breathability.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1 provides a breathable antibacterial silk nano dressing, comprising a base layer made of silk, hemp fiber and cotton fiber, a PE film protective layer and a wound repair layer between the base layer and the protective layer. The wound repair layer is composed of the following components by weight: 180g of polymer fiber loaded with nano silver, 50g of chitosan, 50g of sodium alginate, 30g of bacterial cellulose, 5g of sodium hydroxide, 5g of disodium hydrogen phosphate, 30g of melittin . Wherein, the polymer fiber is a combination of silk fiber, cotton fiber and collagen fiber. The mass of nano-silver in the polymer fiber is 1.8g, and the particle diameter of nano-silver is 10nm.

Embodiment 2

[0019] Embodiment 2 provides a breathable antibacterial silk nano dressing, which includes a base layer made of silk and cotton fibers, a PP film protective layer and a wound repair layer between the base layer and the protective layer. The wound repair layer is composed of the following components by weight: 300g of polymer fibers loaded with nano silver, 100g of chitosan, 100g of sodium alginate, 50g of bacterial cellulose, 15g of sodium dihydrogen phosphate, 15g of triethanolamine, and 80g of magainin . Wherein, the polymer fiber is a combination of silk fiber, cotton fiber and collagen fiber. The mass of nano-silver in the polymer fiber is 6g, and the particle size of nano-silver is 50nm.

Embodiment 3

[0021] Embodiment 3 provides a breathable antibacterial silk nano dressing, which includes a base layer made of silk and hemp fiber, a PVC film protective layer and a wound repair layer between the base layer and the protective layer. The wound repair layer is composed of the following components by weight: 250g of polymer fiber loaded with nano silver, 80g of chitosan, 70g of sodium alginate, 40g of bacterial cellulose, 10g of sodium dihydrogen phosphate, 10g of triethanolamine, and polymyxin E 50g. Wherein, the polymer fiber is a combination of silk fiber, cotton fiber and collagen fiber. The mass of nano-silver in the polymer fiber is 10g, and the particle diameter of nano-silver is 30nm.

[0022] In the present invention, the preparation method of the polymer fiber loaded with nano-silver comprises the following steps: ascorbic acid is added in the silver nitrate aqueous solution to form a nano-silver solution; the polymer fiber material is soaked in the above-mentioned n...

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PUM

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Abstract

The invention provides an air-permeable antibacterial silk nano dressing, which comprises a base layer, a protective layer and a wound repair layer arranged between the base layer and the protective layer. The wound repair layer comprises, by weight, the following components: 18-30 parts of macromolecular fiber loaded with nano silver, 5-10 parts of chitosan, 5-10 parts of sodium alginate, 3-5 parts of bacterial cellulose, 1-3 parts of pH regulator and 3-8 parts of antibacterial peptide, wherein the macromolecular fiber is the combination of silk fiber, cotton fiber and collagen fiber, and theantibacterial peptide is bee toxin, senopus or polyoxin E. The nano dressing has excellent antibacterial and air permeability, can promote wound healing, and has low cost and wide application range.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a breathable and antibacterial silk nano dressing. Background technique [0002] The research on traditional medical dressings has been very rich. These dressings basically have the advantages of absorbing wound fluid and promoting wound healing, and are especially suitable for wound treatment. However, the existing medical dressings are generally thick, and the comfort and air permeability cannot meet the needs of patients, which affects the process of wound repair. Moreover, current medical dressings also have shortcomings such as weak antibacterial ability and high cost. Therefore, it is extremely important to develop a medical dressing with good comfort, strong antibacterial ability and breathability. Contents of the invention [0003] In order to solve the above technical problems, the present invention provides a breathable antibacterial silk nano dressing, which has goo...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/32A61L15/28A61L15/42A61L15/44A61L15/46
CPCA61L15/28A61L15/325A61L15/40A61L15/42A61L15/44A61L15/46A61L2300/104A61L2300/252A61L2300/404C08L5/08C08L5/04C08L1/02
Inventor 李苏杨徐勤霞成清明
Owner SUZHOU BEC BIOLOGICAL TECH