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Pharmaceutical composition for treating functional constipation and preparation method thereof

A functional constipation and composition technology, which is applied in the directions of drug combination, pharmaceutical formula, and medical preparations containing active ingredients, etc., can solve the problems of large surgical damage, many postoperative complications, electrolyte imbalance, etc., and achieves non-toxicity. Side effects, significant curative effect, good defecation effect

Inactive Publication Date: 2018-10-23
THE AFFILIATED HOSPITAL OF TRADITIONAL CHINESE MEDICAL TO SOUTHWEST MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the treatment of functional constipation, modern medicine focuses on symptomatic treatment. There are many drugs, the curative effect is unstable, and drug resistance is easy to develop. If the medication is unreasonable, it can cause melanosis of the colon, aggravate constipation, and even dehydration, electrolyte imbalance, etc. Side effects; Surgical treatment has large damage, inaccurate curative effect, and many postoperative complications

Method used

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  • Pharmaceutical composition for treating functional constipation and preparation method thereof
  • Pharmaceutical composition for treating functional constipation and preparation method thereof
  • Pharmaceutical composition for treating functional constipation and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 Preparation of the composition of the present invention

[0019] Prescription: Atractylodes 600g, Atractylodes 600g, Cistanche 300g, Citrus aurantium 300g, Scrophulariae 450g.

[0020] Preparation Process:

[0021] Weigh 5 kinds of raw materials according to the prescription; soak the raw materials in 7 times the amount of water for 0.5 hours, decoct twice, 1 hour each time. Collect the volatile oil at the same time and set aside; combine the decoction, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.02-1.05 (80°C), let it stand for 12 hours, filter, concentrate the filtrate under reduced pressure to form a thick paste, dry at 100°C, and crush it into Fine powder, evenly sprayed into the above-mentioned volatile oil, airtight for 24 hours, put into capsules, and make 1000 capsules, to get final product.

[0022] 【Properties】This product is a hard capsule, and the content is a light yellow-brown powder; the gas is sli...

Embodiment 2

[0023] Embodiment 2 Preparation of the composition of the present invention

[0024] Prescription: Atractylodes 480g, Atractylodes 480g, Cistanche 210g, Citrus aurantium 210g, Scrophulariae 350g.

[0025] Preparation process: with the preparation process of embodiment 1.

Embodiment 3

[0026] Embodiment 3 Preparation of the composition of the present invention

[0027] Prescription: Atractylodes 720g, Atractylodes 720g, Cistanche 390g, Citrus aurantium 390g, Scrophulariaceae 550g.

[0028] Preparation process: with the preparation process of embodiment 1.

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Abstract

The invention provides a pharmaceutical composition for treating functional constipation. The pharmaceutical composition is prepared from the following bulk drugs by weight: 480 to 720 parts of Rhizoma Atractylodis, 480 to 720 parts of bighead atractylodes rhizomes, 210 to 390 parts of Herba Cistanche, 210 to 390 parts of bitter orange fruit and 350 to 550 parts of Radix Scrophulariae. The invention also provides a preparation method and application of the composition. The composition provided by the invention is reasonable in composition, has good security and substantial curative effect on functional constipation, and is novel drug choice.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating functional constipation, a preparation method and application thereof. Background technique [0002] Functional constipation (fuctional constipation, FC) refers to non-systemic diseases or intestinal diseases caused by primary persistent constipation, also known as habitual constipation or simple constipation. FC is a digestive tract disease with a high incidence, which seriously affects the quality of life of modern people. Traditional Chinese medicine believes that it is mostly caused by accumulated heat in the intestines and stomach, stagnation of qi movement, stagnation of yin and cold, deficiency of qi and yang decline, deficiency of yin and less blood, and the total pathogenesis is abnormal conduction of the intestines. Western medicine divides functional constipation into three types: chronic transit constipation (STC), outlet obstruction constipation (OOC), and mixed constipati...

Claims

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Application Information

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IPC IPC(8): A61K36/808A61P1/10
CPCA61K36/284A61K36/64A61K36/752A61K36/808A61K2300/00
Inventor 肖国辉段国勋徐州李志陈辉赵龙喻玉
Owner THE AFFILIATED HOSPITAL OF TRADITIONAL CHINESE MEDICAL TO SOUTHWEST MEDICAL UNIV
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