Preparation method and application of a ratiometric luminescent carbon dot probe
A technology of carbon dots and probes, which is applied in the field of analytical chemistry, can solve the problems of difficult detection of zinc ions and zinc ions without obvious spectrum and magnetic signals, and achieve the effects of low raw material prices, easy promotion, and mild preparation conditions
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[0025] A method for preparing a ratiometric luminescent carbon dot probe, comprising the following steps:
[0026] The synthetic route of the compound 2-hydroxy-5-methyl-1,3-benzenedicarbaldehyde:
[0027] .
[0028] 1) Synthesis of compound 2-hydroxy-5-methyl-1,3-phthalaldehyde
[0029] Dissolve p-cresol (10 mmol) and hexamethylenetetramine (20 mmol) in a TFA (15 mL) solution, and react under reflux at 110°C for 24 hours under the protection of argon. The reaction solution was cooled to room temperature, hydrochloric acid (4 M, 66 mL) was added, stirred at room temperature for 10 minutes, extracted with dichloromethane and saturated brine, washed three times with saturated brine, the organic layer was rotary evaporated under reduced pressure to remove the solvent, and subjected to column chromatography ( The eluent was dichloromethane), purified to obtain a white flocculent solid, and dried in vacuum to obtain the compound 2-hydroxy-5-methyl-1,3-benzenedicarbaldehyde (yie...
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