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Use of peach gum polysaccharide in preparing medicine for treating or preventing nephritis and pharmaceutical composition

A technology of peach gum polysaccharides and medicines, applied in the field of medicines and pharmaceutical compositions, can solve problems such as treatment problems, transformation of disease properties, and decline in patients' physical fitness, so as to improve biochemical indicators, reduce inflammatory reactions, and improve immunity Effect

Active Publication Date: 2021-05-18
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although this method is direct and effective, it also has its insurmountable shortcomings: first, the continuous increase in the dosage of antibiotics will increase the resistance of bacteria; Some patients have a history of allergies to antibiotics, and the treatment of these patients is a difficult problem for doctors; fourth, the course of the disease is protracted, which easily leads to complications and transformation of the nature of the disease, making the disease more difficult to treat and difficult to treat, and the treatment effect cannot be tolerated. optimism

Method used

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  • Use of peach gum polysaccharide in preparing medicine for treating or preventing nephritis and pharmaceutical composition
  • Use of peach gum polysaccharide in preparing medicine for treating or preventing nephritis and pharmaceutical composition
  • Use of peach gum polysaccharide in preparing medicine for treating or preventing nephritis and pharmaceutical composition

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Embodiment

[0047] Below in conjunction with embodiment, feature and performance of the present invention are described in further detail:

[0048] 1. Experimental materials

[0049]Medicines: levofloxacin hydrochloride (YX. Wantong Pharmaceutical Co., Ltd.), peach gum polysaccharide (self-made pure peach gum polysaccharide, its preparation method can be: a preparation method of peach gum polysaccharide, comprising the following steps: 1. Peach gum is ground into peach gum powder, sieved to remove large particles of impurities, 1 mass part of peach gum is added to 100 mass parts of distilled water, soaked in a constant temperature oven at 60°C for 36 hours, heated and boiled for 5 hours, using Gauze filtration, get filtrate.Filtrate is placed in rotary evaporator and concentrated, obtains concentrated filtrate.2, dichloromethane and n-hexane mixed solvent are joined in concentrated filtrate and both are mixed, separate liquid by separatory funnel, repeat many times Once, until the middle...

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Abstract

The invention provides a use of peach gum polysaccharide in the preparation of medicines for treating or preventing nephritis and a pharmaceutical composition, belonging to the technical field of traditional Chinese medicines. The inventor found that peach gum polysaccharide can effectively improve the biochemical indicators of nephritis, improve immunity, reduce inflammation, restore the vitality of renal corpuscle, and has a certain antibacterial effect, which can be used for the treatment of nephritis and other urinary system diseases. It can be used alone or in combination with other drugs to prepare drugs for the prevention or treatment of diseases related to renal corpuscle injury, and to relieve the damage caused by other drugs to renal corpuscle cells, which is a disease caused by renal corpuscle cell damage. Provide new treatment methods and ideas.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to the use of peach gum polysaccharides in the preparation of medicines for treating or preventing nephritis and a pharmaceutical composition. Background technique [0002] In the prior art, in the process of treating nephritis or other urinary system infections, the conventional treatment method of Western medicine is generally adopted: large doses of antibiotics are used for treatment. Although this method is direct and effective, it also has its insurmountable shortcomings: first, the continuous increase in the dose of antibiotics will increase the resistance of bacteria; second, large doses of antibiotics will damage other beneficial microorganisms in the human body and cause the decline of the patient's physical fitness; Some patients have a history of allergies to antibiotics, and the treatment of these patients is a difficult problem for doctors; fourth,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A23L33/125A61P13/12A61P29/00A61P31/04A61P37/02A61P37/06
CPCA23V2002/00A61K31/715A23L33/125A61P13/12A61P29/00A61P31/04A61P37/02A61P37/06A23V2200/30A23V2200/324A23V2250/502
Inventor 任永申张霏霏白杰刘吉开杜冬云李燕刘新桥
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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