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Individualized 3D printing multifunctional artificial orbital implant and preparation method thereof

A 3D printing, prosthetic eye seat technology, applied in 3D modeling, prostheses, eye implants, etc., can solve the problem of inability to individualize selection, achieve good clinical application value, high matching, and improve appearance.

Pending Publication Date: 2018-12-25
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In order to overcome the shortcoming that the current conventional prosthetic eye sockets cannot be individually selected according to the patient's own characteristics, the present invention provides an individualized 3D printed multifunctional prosthetic eye socket and its preparation method, which can effectively improve the biological function of the artificial eye socket. Improve the medical performance, promote the rapid vascularization of the eye seat, increase the matching degree between the affected side and the healthy side, improve the activity of the artificial eye seat, and finally improve the appearance of the patient and improve the quality of life of the patient

Method used

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  • Individualized 3D printing multifunctional artificial orbital implant and preparation method thereof
  • Individualized 3D printing multifunctional artificial orbital implant and preparation method thereof
  • Individualized 3D printing multifunctional artificial orbital implant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] The concretely implemented prosthetic eye seat 1 is directly printed out by the digital model of the prosthetic eye seat using 3D printing technology.

[0067] The digital model of the prosthetic eye seat is obtained through CT scanning of the medical digital imaging and communication (DICOM) data of the orbital bony structure and soft tissue in the patient's eye and healthy eye, and the medical digital imaging of the orbital bony structure and soft tissue structure in the orbit Segmentation, three-dimensional modeling and analysis of data and communication (DICOM) to construct and obtain individualized digital models.

[0068] The specific implementation takes the 3DMed medical image processing and analysis system as the development platform, develops the image segmentation algorithm as the core, and constructs an interactive image segmentation method.

[0069] The specific construction method of the digital model of the prosthetic eye seat is as follows:

[0070] 1) ...

Embodiment 2

[0101] Embodiment 2: animal experiments

[0102] The 3D printed hydroxyapatite prosthetic eye socket prepared in Example 1 was used as the experimental group, and the hydroxyapatite eye socket scaffold made of pore-forming agent was used as the control group to evaluate the vascularization efficiency and eye socket mobility of the eye socket material . The result is as Figure 6 Shown: The 3D printed hydroxyapatite prosthetic eye seat has a higher density of neovascularization than that of the control group (A is the control group, B is the experimental group, and the arrow shows the neovascularization). Figure 7 Shown is the range of movement of the eye socket in the upward, downward, left and right directions after implantation of the artificial eye socket, which shows that the artificial eye socket has good mobility.

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Abstract

The invention discloses an individualized 3D printing multifunctional artificial orbital implant and a preparation method thereof. The surface of the artificial orbital implant has a porous structure,the pores of the porous structure are circular pores, and the porous structure of the surface is arranged in a gradient manner, and the pores in the porous structure are arranged on the surface of the artificial orbital implant spaced apart; a special structure for fixing four extraocular muscles is arranged on the artificial orbital implant, the special structure consists of two elliptical holeswhich penetrate each other and are arranged close to each other, the preset sutures on the extraocular muscles pass through the two elliptical foramen and are knotted and fixed at the intersection of30 degree north latitude and 0 degree, 90 degree, 180 degree and 270 degree longitude respectively. The prosthetic orbital implant is printed directly by the digital model of the prosthetic orbital implant using 3D printing technology. The artificial orbital implant has high matching degree with the healthy eye and reduces the risk of exposure and infection after implantation of the orbital implant. The artificial orbital implant has good mobility and good simulation effect with individualized ophthalmic prosthesis, and has good clinical application value.

Description

technical field [0001] The invention relates to medical materials and a preparation method thereof, in particular to an individualized 3D printed multifunctional prosthetic eye seat and a preparation method thereof. Background technique [0002] Enucleation is currently the ultimate surgical treatment for absolute glaucoma, severe ocular rupture, and intraocular malignant tumors. Heavy mental and psychological burden. Selecting eye seat implantation to implant a suitable prosthetic eye seat to compensate for the loss of orbital content and wearing a suitable prosthetic eye piece is an ideal treatment plan to repair the missing eyeball and restore the appearance of the face. [0003] Most of the eye sockets used clinically are spherical eye sockets with a fixed shape, which cannot be selected individually according to the characteristics of the patient's own orbit. At present, the main cause of enucleation in China is ocular trauma. Patients with complex ocular trauma often...

Claims

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Application Information

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IPC IPC(8): G06T17/00G06T7/11G06K9/62A61F2/14
CPCG06T7/11G06T17/00A61F2/14A61F2240/002G06T2207/20104G06F18/23213B29D11/02
Inventor 叶娟王嫦君苟中入宁晴瑶汪伊洁
Owner ZHEJIANG UNIV
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