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A Chinese medicinal composition for treating senile skin pruritus, and a preparation method and application thereof

A technology for skin pruritus and composition, which is applied in the field of traditional Chinese medicine composition, can solve problems such as mixed deficiency and excess, and achieve the effects of improving sleep, improving quality of life, and improving the frequency of scratching movements

Pending Publication Date: 2019-01-11
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment is mostly based on traditional Chinese medicines for nourishing blood and dispelling wind, ignoring the fact that the disease is caused by rheumatic fever and mixed with deficiency and excess during the onset period.

Method used

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  • A Chinese medicinal composition for treating senile skin pruritus, and a preparation method and application thereof
  • A Chinese medicinal composition for treating senile skin pruritus, and a preparation method and application thereof
  • A Chinese medicinal composition for treating senile skin pruritus, and a preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The preparation (granule) of embodiment 1 pharmaceutical preparation of the present invention

[0027] Angelica 320g, Pittosporum bark 320g, Vermicelli 288g, Chuanxiong 144g, Rehmannia 288g, Paeoniae Alba 176g, Fangfeng 160g, Zhishouwu 240g, Tribulus terrestris 288g, Astragalus 192g, Licorice 16g.

[0028] Take the medicinal material according to the above prescription, add 10 times of water to decoct for 60 minutes, filter, add 8 times of water to the medicinal residue, decoct for 60 minutes, filter, combine the two decoction liquids, concentrate under reduced pressure, use an appropriate amount of dextrin as the base material, Fluidized bed one-step granulation, packaging, made into 1000g, 10 grams per package, 3 times a day, 2 packages each time.

Embodiment 2

[0029] The preparation (granule) of embodiment 2 pharmaceutical preparations of the present invention

[0030] Angelica 256g, Pittosporum bark 320g, Vermicelli 320g, Chuanxiong 144g, Rehmannia 256g, Paeoniae Alba 192g, Fangfeng 192g, Zhishouwu 256g, Tribulus terrestris 320g, Astragalus 192g, Licorice 10.7g.

[0031] Take the medicinal materials according to the above prescription, add 12 times of water to decoct for 60 minutes, filter, add 10 times of water to the dregs of the medicine, decoct for 45 minutes, and filter. Combine two decoctions, concentrate under reduced pressure to a relative density of 1.25-1.30, add appropriate amount of dextrin, magnesium stearate, mix well, wet granulate, make 1000g, pack, 10 grams per bag, 3 times a day, 2 packs each time.

Embodiment 3

[0032] The preparation (granule) of embodiment 3 pharmaceutical preparations of the present invention

[0033] Angelica 304g, Pittosporum bark 288g, Vermicelli 320g, Chuanxiong 152g, Rehmannia 240g, Paeoniae Alba 208g, Fangfeng 192g, Zhishouwu 240g, Tribulus terrestris 304g, Astragalus 160g, Licorice 19g.

[0034] Take the medicinal materials according to the above prescription, add 70% ethanol with a weight ratio of 6 times the medicinal materials, reflux extraction twice, each time for 60 minutes, filter, combine the filtrate and recover the ethanol until there is no alcohol smell, concentrate the medicinal solution, dry it, and extract powder Add an appropriate amount of dextrin, mix evenly, add an appropriate amount of binder to granulate, make 1000g, divide into packages, 10g per pack, 3 times a day, 2 packs each time.

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Abstract

The invention discloses a Chinese medicinal composition for treating senile skin pruritus, which is mainly prepared from the following raw materials in parts by weight: Angelica sinensis 20-30 part, paulownia bark 25-35 parts, Cudweed Herb 25-35 parts, szechwan lovage rhizome 10-15 parts, Rhizome of rehmannia 20-30 parts, white peony root 15-20 parts, Saposhnikovia divaricata 15-20 parts, radix Polygoni Multiflori Preparata 20-30 parts, tribulus terrestris 25-35 parts, astragalus root 15-20 parts, and liquorice 1-2 parts. In addition, the invention also discloses a preparation method and an application of the traditional Chinese medicine composition. As prove by clinical tests, that Chinese medicinal composition of the invention alleviate the pruritus symptoms of senile skin pruritus, increases the moisture content and oil content of the epidermis, has the effect of moistening skin and relieving itch, and can improve the symptoms of constipation and dry mouth of the senile to a certainextent, slightly improve sleep, reduce the inducement of itch attack, and improve the life quality of the patient.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating senile skin pruritus. In addition, the present invention also relates to the preparation method and application of the traditional Chinese medicine composition. Background technique [0002] Senile pruritus is a common primary skin pruritus disease caused by internal diseases such as liver and kidney diseases, endocrine diseases, tumors, or external factors such as medicine and food. Due to the complex pathogenesis and lack of effective treatment Means, so that the quality of daily life of the elderly has been seriously affected. The disease mostly occurs in men over 60 years old. With the improvement of medical technology, the popularization of the concept of health preservation, and the gradual increase of the average life expectancy of the population, the prevalence rate of the disease will increase according...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P17/04
CPCA61K36/185A61K36/232A61K36/236A61K36/238A61K36/28A61K36/48A61K36/481A61K36/484A61K36/65A61K36/704A61K36/71A61K36/804A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P17/04A61K2300/00
Inventor 张慧敏徐昌泰徐菱刘力王雪娇高春洁
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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