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A composition containing NADH and a preparation method and an application thereof

A technology of composition and extract, which is applied in the field of medicine, can solve the problems of melatonin, such as unclear effect of improving sleep, drug dependence, toxic and side effects, etc., and achieve the effect of enhancing the activity of key enzymes, enhancing physiological functions, and improving sleep

Inactive Publication Date: 2019-01-11
HOBOOMLIFE BIO TECH SHENZHEN CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hypnotics commonly used clinically at present include benzodiazepines, barbiturates and other non-barbiturates. The effect of treating insomnia is relatively obvious, but it has a greater impact on the liver and kidney, and users are prone to drug reactions. Dependence, usually increasing the dosage of medicine to maintain the effect, but also produce a lot of toxic side effects, so it is not suitable for long-term use of drugs
The effect of melatonin on improving sleep is not yet clear. Long-term or high-dose melatonin may cause harm to the human body, such as significantly inhibiting the function of the human reproductive system

Method used

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  • A composition containing NADH and a preparation method and an application thereof
  • A composition containing NADH and a preparation method and an application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Preparation of NADH-containing compositions

[0042] A1. First pass the dried raw and auxiliary materials through a 30-80 mesh sieve, so that the particle size distribution is uniform, the fluidity is better, and the raw and auxiliary materials are kept dry;

[0043]A2. Then carry out proportioning and weighing of the screened raw materials, including the necessary components: 1-10 parts by weight of NADH, 1-10 parts by weight of grape seed extract, 1-10 parts by weight of ginsenoside PPD, 1 -10 parts by weight of ginsenoside RH2, 1-10 parts by weight of chondroitin sulfate, 1-10 parts by weight of bird's nest acid, 1-10 parts by weight of s-adenosylmethionine, and 1-10 parts by weight of γ-aminobutyric acid acid, 1-10 parts by weight of protein oligopeptide, 1-10 parts by weight of soybean lecithin, 1-10 parts by weight of bitter melon seed extract, including optional components: 1-4 parts by weight of vitamin B6, 1 -4 parts by weight of Radix Notoginseng, 1-4 parts b...

Embodiment 2

[0046] Preparation of NADH-containing compositions

[0047] B1. First pass the dried raw and auxiliary materials through a 60-mesh sieve, so that the particle size distribution is uniform, the fluidity is better, and the raw and auxiliary materials are kept dry;

[0048] B2. Then carry out proportioning and weighing of the screened raw and auxiliary materials, including the necessary components: 1-10 parts by weight of NADH, 1-10 parts by weight of grape seed extract, 1-10 parts by weight of ginsenoside PPD, 1-10 parts by weight of ginsenoside RH2, 1-10 parts by weight of chondroitin sulfate, 1-10 parts by weight of bird's nest acid, 1-10 parts by weight of s-adenosylmethionine, 1-10 parts by weight of γ-amino Butyric acid, 1-10 parts by weight of protein oligopeptide, 1-10 parts by weight of soybean lecithin, 1-10 parts by weight of bitter melon seed extract, including optional components: 1-4 parts by weight of vitamin B6, 1-4 parts by weight of Panax notoginseng, 1-4 parts...

Embodiment 3

[0054] Preparation of NADH-containing compositions

[0055] C1. Preparation of contents: first pass the dried raw and auxiliary materials through a 60-mesh sieve, keep the raw and auxiliary materials dry, then carry out proportioning and weighing of the screened raw materials, and then mix them evenly;

[0056] C2, preparation of soft capsules: add glycerin and water into the sol tank, then add gelatin and related auxiliary materials respectively, stir, and vacuum degas to obtain soft capsules;

[0057] C3. Capsule preparation: the above-mentioned prepared contents and soft capsule body are subjected to the steps of pressing pills, shaping and drying, washing pills, drying pills, picking pills and packaging to obtain soft capsules.

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Abstract

The invention discloses a composition containing NADH, a preparation method and an application thereof, which relate to the technical field of medicine, in particular to a required component: NADH, grape seed extract, ginsenoside PPD, ginsenoside RH2, chondroitin sulfate, bird nest acid, s-adenosylmethionine, gamma-aminobutyric ccid, protein oligopeptide, soybean Lecithin, and balsam pear seed extract. Through the synergistic action among the components, the composition has good efficacy in improving sleep problems, is non-toxic and harmless to the user, and has no adverse side effects.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a composition containing NADH and its preparation method and application. Background technique [0002] Sleep is the most important part of life, people spend about 30% of their time in sleep. Insomnia is a disease of sleep disorders, which is a common clinical manifestation of various physical, mental and behavioral diseases, and seriously affects people's physical and mental health, quality of life and work efficiency. A variety of recent epidemiological survey data show that about 35.2% of people abroad have insomnia to varying degrees; a statistical data from the Ministry of Health shows that at present, the number of insomniacs in China has reached 1.2 to 1.4 million, and the insomnia rate is as high as 10 to 20. %. According to the statistics of the World Health Organization (WHO), the prevalence of sleep disorders in my country is as high as 42.7%, and there are about 5...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K36/8984A61K9/16A61K9/28A61K9/48A61P25/20A61P37/04A61K31/197A61K31/4415A61K31/7012A61K31/704A61K31/7076A61K31/7084A61K31/737A61K31/575
CPCA61K9/16A61K9/282A61K9/4816A61K9/4866A61K31/197A61K31/4415A61K31/575A61K31/7012A61K31/704A61K31/7076A61K31/7084A61K31/737A61K36/254A61K36/258A61K36/42A61K36/483A61K36/484A61K36/538A61K36/69A61K36/704A61K36/87A61K36/8969A61K36/8984A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61P25/20A61P37/04A61K2300/00
Inventor 陈建生刘喜元张慧梁倩李峰胡欢
Owner HOBOOMLIFE BIO TECH SHENZHEN CO LTD
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