Application of retinoic acid in preparation of drugs for improving prognosis of cryptorchidism

A technology of retinoic acid and cryptorchidism, applied in the field of medicine, can solve the problems of inability to effectively improve children with cryptorchidism, safety and ethical issues, and achieve the effects of improving treatment strategies, improving spermatogenic function, and improving prognosis.
CN109223752AInactive Publication Date: 2019-01-18CHILDRENS HOSPITAL OF CHONGQING MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
CHILDRENS HOSPITAL OF CHONGQING MEDICAL UNIV
Publication Date
2019-01-18
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the application of retinoic acid in preparation of drugs for improving prognosis of cryptorchidism, and belongs to the technical field of medicine. The drug is mainly composedof retinoic acid, which can improve the infertility of cryptorchidism patients, and can improve the spermatogenesis function of cryptorchidism patients by improving the oxidative stress level and apoptosis level of cryptorchidism patients' testis tissue and the expression level of blood-testis barrier-associated protein. This provides a basis for improving the clinical treatment strategy for cryptorchidism and improving the prognosis of cryptorchidism.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to the application of retinoic acid in the preparation of drugs for improving the prognosis of patients with cryptorchidism. Background technique

[0002] Cryptorchidism is one of the most common congenital malformations in male children. It usually shows that one or both testicles cannot descend into the scrotum for a long time. The incidence rate of general newborns is 2%-5%. With the increased risk of environmental factors and biological exposure during pregnancy and after birth, the incidence of cryptorchidism in children tends to increase gradually. In recent years, foreign surveys have found that the incidence of adult azoospermia in children with unilateral cryptorchidism is about 13%; in children with untreated bilateral cryptorchidism, the incidence of azoospermia is as high as 89%. The measures taken in current clinical treatment can only improve the position...

Claims

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