1,2,4-thiadiazole compound and preparation method and application thereof
A compound and an independent technology, applied in the field of 1,2,4-thiadiazole compounds and their preparation, can solve the problems of inability to solve the loss of light, the material of the light emitting layer needs to be improved, etc., to ensure thermal stability and compactness. The effect of improving the performance and improving the current efficiency
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Embodiment 1
[0064]
[0065] (1) In a 500mL three-necked flask, put 5-bromo-3-chloro-1,2,4-thiadiazole (19.94g, 100mmol), phenanthrene-9-ylboronic acid (22.20g, 100mmol), cesium carbonate (48.87g, 150mmol), add 200mL toluene, under nitrogen atmosphere, add [1,1'-bis(diphenylphosphino)ferrocene]palladium dichloride (1.46g, 2mmol), heat up to 50~ React at 100°C for 4 to 48 hours, monitor the completion of the reaction by liquid phase monitoring, cool to room temperature, wash with water, filter, concentrate, and separate by column chromatography to obtain 5-bromo-3-(phenanthrene-9-yl)-1,2,4- Thiadiazole 25.25g, yield 74%;
[0066] (2) In a 500mL three-necked flask, put 5-bromo-3-(phenanthrene-9-yl)-1,2,4-thiadiazole (17.06g, 50mmol), 4-tert-butylphenylboronic acid (8.90 g, 50mmol), potassium carbonate (13.82g, 100mmol), add 150mL toluene, 50mL ethanol and 50mL water, under nitrogen atmosphere, add tetrakis (triphenylphosphine) palladium (0.12g, 0.1mmol), heat up to 50~ React at 100°C fo...
Embodiment 2
[0069]
[0070]According to the same method as Example 1, prepare the target compound in the above formula (compared with Example 1, the reactant of each corresponding step can be different, but the reactant molar ratio, reaction conditions are identical), obtain final product 17.62g, Yield 85%. Mass spectrometer MALDI-TOF-MS (m / z) = 414.5266, theoretical molecular weight: 414.5260; Anal.Calcd for C 28 h 18 N 2 (%): C 81.13, H 4.38, N 6.67, Found: C 81.14, H 4.38, N 6.65.
Embodiment 3
[0072]
[0073] According to the same method as Example 1, prepare the target compound in the above formula (compared with Example 1, the reactant of each corresponding step can be different, but the reactant molar ratio, reaction conditions are identical), obtain final product 20.52g, Yield 81%. Mass spectrometer MALDI-TOF-MS (m / z) = 506.6664, theoretical molecular weight: 506.6670; Anal.Calcd for C 35 h 26 N 2 (%): C 82.97, H 5.17, N 5.53, Found: C 82.95, H 5.18, N 5.53.
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