Drug-coated balloon catheter

A technology of drug-coated and balloon catheters, which is applied in the field of medical devices, can solve the problems of reducing the safety of devices, reducing the dosage of drug-coated balloons, and affecting the effectiveness of devices, so as to reduce the loss rate of drugs and reduce the initial load. Drug dosage, effect of reducing metabolic burden

Pending Publication Date: 2019-02-26
HANGZHOU WEIQIANG MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, during the delivery of the drug-coated balloon catheter in the blood vessel, the drug loss rate is as high as 50% due to the high-speed flow of blood, thereby reducing the amount of drug that the drug-coated balloon can release in the lesion. The effectiveness of the device; at the same time, after the drug washed away by the blood falls off, it will also block the distal blood vessels, increase the metabolic burden of the body, and reduce the safety of the device
In addition, in order to ensure that a sufficient amount of drug reaches the lesion, the existing technology also adopts the method of increasing the initial drug loading of the balloon, but this method will not only increase the cost of the device, but also increase the metabolic burden of the body and reduce the safety of the device. sex

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] See figure 1 and figure 2 In the drug-coated balloon catheter provided in this embodiment, the pushing device 300 includes a pushing catheter 310 with a certain axial length. A drug-coated balloon 100 is fixed at the distal end of the push catheter 310 . The fixing method of the drug-coated balloon 100 may be common technical means in the field such as welding or bonding, which will not be repeated here. The drug-coated balloon 100 is housed in the sheath 220 after being folded and rolled. The proximal end and the distal end of the drug-coated balloon 100 are conical, and the middle part is a roughly cylindrical working section. The drug-coated balloon 100 has a length in the range of 30-320 mm. The diameter range of the working section is 2-15mm. The length of the working section (ie, the effective length of the drug-coated balloon 100) ranges from 20-300 mm. The effective length refers to the length that can be attached to the inner wall of the blood vessel aft...

Embodiment 2

[0070] The structure of the drug-coated balloon catheter provided in this embodiment is basically the same as that of the drug-coated balloon catheter provided in Example 1. The difference is that in this embodiment, two balloons are provided, and the two balloons The distance between them can be adjusted.

[0071] Specifically, see Figure 11 The pushing device 300 includes a pushing conduit 310 and a sliding conduit 340 that is movably sleeved on the outside of the pushing conduit 310 and can move relative to the pushing conduit 310 in the axial direction. The distal end of the pushing catheter 310 is fixedly provided with at least one drug-coated balloon 100 . The distal end of the sliding catheter 340 is provided with at least one second balloon 400 . It can be understood that, in other embodiments, the number of sliding catheters 340 can be set according to the actual situation, and generally 1-2 are preferably set. Correspondingly, the number of second balloons 400 at ...

Embodiment 3

[0094] The structure of the drug-coated balloon catheter provided in this embodiment is basically the same as the drug-coated balloon catheter provided in Example 2, the difference is that the positional relationship between the pushing catheter and the sliding catheter in this embodiment is the same as that in Example 2. Two push conduits and sliding conduits have different positional relationships.

[0095] Specifically, see Figure 20 , the drug-coated balloon catheter further includes at least one sliding catheter 340 , the sliding catheter 340 moves relative to the pushing catheter 310 in the axial direction, and at least one second balloon 400 is provided at the distal end of the sliding catheter 340 .

[0096] In the drug-coated balloon catheter provided in this embodiment, the distal end of the pushing catheter 310 is connected to the first pushing branch 312 connected with the drug-coated balloon 100 . The distal end of the sliding catheter 340 is connected to the se...

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PUM

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Abstract

The invention discloses a drug-coated balloon catheter comprises a pushing catheter with a certain axial length, at least one drug-coated balloon arranged at the distal end of the pushing catheter anda sheath movably sheathed outside the drug-coated balloon. The sheath can move axially along the push catheter and the drug coated balloon is received within the sheath prior to expansion. In the drug-coated balloon catheter of the present invention, the sheath has a protective effect on the drug coating on the surface of the drug-coated balloon during the transportation process, and the blood flow is prevented from scouring the drug coating. After reaching the lesion, the slidable sheath is withdrawn proximally. The drug-coated balloon protrudes from the sheath and is exposed to the vascularenvironment to be filled, thereby effectively reducing the rate of drug loss during delivery and improving the effectiveness and safety of the drug-coated balloon catheter.

Description

technical field [0001] The invention belongs to the technical field of medical devices and relates to interventional medical devices, in particular to a drug-coated balloon catheter. Background technique [0002] Arterial stenosis is a common disease, and the treatment methods for arterial stenosis mainly include the use of bare balloon dilation at the lesion site, implantation of bare stents or drug stents, and the like. The above-mentioned treatment methods all have different defects. [0003] Drug-coated balloon catheter refers to a balloon catheter loaded with a drug coating on the surface of an ordinary bare balloon. The drug coating is eluted from the surface of the balloon and released to the vessel wall, which can further inhibit the proliferation of smooth muscle cells and prevent restenosis of vessels. Therefore, the drug-coated balloon catheter can not only establish a channel for blood supply through balloon expansion, but also avoid defects such as in-stent re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M29/04
CPCA61M29/02A61M31/00A61M2205/0238A61M2210/12A61M2210/005
Inventor 张庭超李敬
Owner HANGZHOU WEIQIANG MEDICAL TECH CO LTD
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