Fragrant sarcococca herb rhinitis spray and preparation method thereof

A technology of Qingxianggui rhinitis, which is applied in the field of Qingxianggui rhinitis spray and its preparation, can solve the problems of inability to maintain a long-term curative effect, short action time, inconvenient taking, etc., and achieves no toxic side effects, less harmful ingredients, and high composition simple effect

Inactive Publication Date: 2019-03-01
海南金香远药业科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the medicines for treating rhinitis and rhinitis are mainly divided into two categories, one is external medicine, such as spray or nasal drops, its action time is short, it cannot maintain long-term curative effect, and it is easy to relapse after stopping the medicine; the other is internal medicine. Taking medicine, this kind of medicine is mainly traditional Chinese medicine, although it has been used clinically, the curative effect is generally not good, and it is inconvenient to take

Method used

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  • Fragrant sarcococca herb rhinitis spray and preparation method thereof
  • Fragrant sarcococca herb rhinitis spray and preparation method thereof
  • Fragrant sarcococca herb rhinitis spray and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0031] Raw materials of Qingxianggui rhinitis spray (parts by weight): 1 part of Dayeqingxianggui extract, 0.4 part of Hedyotis diffusa extract, 0.05 part of menthol, 0.2 part of penetrating agent, 2 parts of solubilizer, 2 parts of ethanol, 94.35 parts of water share.

[0032] The solubilizer is Tween 80.

[0033] The penetrating agent is potassium lauryl decanoyl acid.

[0034] The Dayeqingxianggui extract is prepared by the following method, wherein the parts are parts by weight: dry the leaves of Dayeqingxianggui at 50°C to constant weight, pulverize them, and pass through a 40-mesh sieve to obtain a coarse powder. Mix 3 parts of powder and 20 parts of ethanol aqueous solution with a mass fraction of 70%, stir at 200 rpm for 30 minutes, sonicate at 35°C for 30 minutes, let stand for 15 minutes, then sonicate at 35°C for 30 minutes, and use a 200-mesh filter cloth Filtration, the filtrate was concentrated under reduced pressure at 35°C and an absolute pressure of 0.02MPa to...

Embodiment 2

[0038] Raw materials of Qingxianggui rhinitis spray (parts by weight): 1 part of Dayeqingxianggui extract, 0.4 part of Hedyotis diffusa extract, 0.05 part of menthol, 0.2 part of penetrating agent, 2 parts of solubilizer, 2 parts of ethanol, 94.35 parts of water share.

[0039] The solubilizer is Tween 80.

[0040] The penetrating agent is potassium lauryl decanoyl acid.

[0041] The Dayeqingxianggui extract is prepared by the following method, wherein the parts are parts by weight: dry the leaves of Dayeqingxianggui at 50°C to constant weight, pulverize them, and pass through a 40-mesh sieve to obtain a coarse powder. Mix 3 parts of powder and 20 parts of ethanol aqueous solution with a mass fraction of 70%, stir at 200 rpm for 30 minutes, sonicate at 35°C for 30 minutes, let stand for 15 minutes, then sonicate at 35°C for 30 minutes, and use a 200-mesh filter cloth Filtration, the filtrate was concentrated under reduced pressure at 35°C and an absolute pressure of 0.02MPa ...

Embodiment 3

[0045] Raw materials of Qingxianggui rhinitis spray (parts by weight): 1 part of Dayeqingxianggui extract, 0.4 part of Dimai extract, 0.4 part of Hedyotis diffusa extract, 0.05 part of menthol, 0.2 part of penetrant, 2 parts of solubilizer , 2 parts of ethanol, 93.95 parts of water.

[0046] The solubilizer is Tween 80.

[0047] The penetrating agent is potassium lauryl decanoyl acid.

[0048] The Dayeqingxianggui extract is prepared by the following method, wherein the parts are parts by weight: dry the leaves of Dayeqingxianggui at 50°C to constant weight, pulverize them, and pass through a 40-mesh sieve to obtain a coarse powder. Mix 3 parts of powder and 20 parts of ethanol aqueous solution with a mass fraction of 70%, stir at 200 rpm for 30 minutes, sonicate at 35°C for 30 minutes, let stand for 15 minutes, then sonicate at 35°C for 30 minutes, and use a 200-mesh filter cloth Filtration, the filtrate was concentrated under reduced pressure at 35°C and an absolute pressu...

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Abstract

The invention discloses a fragrant sarcococca herb rhinitis spray and a preparation method thereof. The fragrant sarcococca herb rhinitis spray comprises, by weight, the following raw materials: 0.5-1.5 parts of large leaf fragrant sarcococca herb extract, 0.2-0.6 part of oldenlandia diffusa extract, 0.01-0.1 part of menthol, 0.1-0.3 part of penetrant, 1-3 parts of solubilizer and 1-3 parts of ethanol, 90-100 parts of water. According to the fragrant sarcococca herb rhinitis spray and the preparation method thereof, the fragrant sarcococca herb rhinitis spray have the advantages that the obtained fragrant sarcococca herb rhinitis spray uses natural extracts, the components are simple, the use is convenient and safe, the effects of resisting bacteria and diminishing inflammation are achieved, the fragrant sarcococca herb rhinitis spray has obvious treatment effect on various chronic rhinitis and allergic rhinitis, the cure rate is high, the fragrant sarcococca herb rhinitis spray has notoxic or side effects.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a Qingxianggui rhinitis spray and a preparation method thereof. Background technique [0002] Rhinitis is a common disease, especially in today's increasingly serious environmental pollution and more and more extreme weather, there are more and more rhinitis patients, and the age tends to be younger. Rhinitis seems to be a minor disease, but in fact it is very harmful. It greatly affects the five sense organs of the human body during the onset period, and brings great pain to the work and life of rhinitis patients. Failure to receive effective treatment for a long time can also induce a variety of serious diseases, even life-threatening. [0003] Rhinitis is an inflammatory disease of the nasal cavity, which is the inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61K9/12A61P11/02A61P37/08A61K31/045
CPCA61K9/0043A61K9/12A61K31/045A61K36/185A61K36/748A61K47/26A61K2236/17A61K2236/333A61K2236/51A61K2236/53A61P11/02A61P37/08A61K2300/00
Inventor 王志勇
Owner 海南金香远药业科技有限公司
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