Use of mxene, guided bone tissue regeneration material and preparation method thereof

Abstract

The invention discloses the use of MXene, a material for guiding bone tissue regeneration and a preparation method thereof, and relates to the field of biomedical materials, the use of MXene materials in bone tissue materials; the material for guiding bone tissue regeneration includes, in parts by mass, hydroxyapatite 5~ 30 parts, 70~95 parts of MXene. The preparation method of guided bone tissue regeneration material comprises the following steps: step 1, mixing the aqueous solution of MXene and hydroxyapatite nanowires, stirring and mixing evenly with magnetic force, forming a mixture for use; step 2, the mixture obtained in step 1, passing through an ultrasonic water bath Processing: step 3, suction filtration, removing water to obtain the finished product. The inventive application of the MXene material as the raw material of the bone tissue material, the material produced by the composite of MXene and hydroxyapatite nanowires not only has good biocompatibility and osteoconductivity, but also can meet the requirements of guided bone tissue regeneration technology For material requirements, the invention provides a novel material for bone tissue engineering materials.

Description

technical field [0001] The invention relates to the field of biomedical materials, especially the use of MXene, a material for guiding bone tissue regeneration and a preparation method thereof. Background technique [0002] Guided Tissue Regeneration (Guided Tissue Regeneration, GTR) is a surgical method to place a physical barrier to selectively separate different periodontal tissues, prevent gingival epithelium and gingival connective tissue from growing to the root surface, create space, and induce periodontal tissue. Periodontal ligament cells with tissue regeneration potential move coronally, grow and differentiate, realize periodontal ligament, alveolar bone, and cementum regeneration, and form new periodontal attachments. Guided bone regeneration (GBR) technology is currently one of the effective methods to solve bone defects around implants, so as to achieve vertical and horizontal bone augmentation of the alveolar ridge. [0003] So far, no material has been found ...

AI Technical Summary

Problems solved by technology

MXene material has a two-dimensional structure similar to graphene, and has both surface hydrophilicity, metal conductivity, and excellent electrochemical properties. It is easy to disperse into a colloidal solution. Considering that the strength of the material may drop sharply in the blood environment, it cannot play a supporting role in maintaining space

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