Traditional Chinese medicine composition for treating nausea and vomiting caused by chemotherapy, traditional Chinese medicine decoction-free granules and application and belongs to the technical field of traditional Chinese medicine

Abstract

The invention relates to a traditional Chinese medicine composition for treating nausea and vomiting caused by chemotherapy, traditional Chinese medicine decoction-free granules and application and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following raw materials: 6-15 parts of ginger processed pinellia, 10-15parts of dried ginger, 6-15 parts of exocarpium citri grandis, 10-15 parts of white poria, 3-12 parts of rice water processed fructus aurantii, 10-15 parts of pogostemon cablin, 2-4 parts of preparedrhizoma coptidis with rhizoma zingiberis recens juice, 3-5 parts of liquor processed scutellaria baicalensis, 15-30 parts of reed rhizome, 5-12 parts of bamboo shavings, 5-9 parts of perilla leaves, 9-15 parts of codonopsis pilosula Nnannf and 2-6 parts of raw licorice roots. The traditional Chinese medicine decoction-free granules are prepared from the above-mentioned single traditional Chinese medicine formula granules by weight. The traditional Chinese medicine composition and the traditional Chinese medicine decoction-free granules are applied to preparation of drugs for treating nausea and vomiting caused by chemotherapy. The traditional Chinese medicine composition has the advantages of replenishing qi, strengthening spleen, invigorating the stomach, calming the adverse-rising energy, eliminating phlegm, regulating body immunity and inhibiting tumor growth; synergizing with chemotherapeutic drugs to achieve enhanced sensitivity, alleviating vomiting symptoms; and regulating digestive tract functions.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating nausea and vomiting caused by chemotherapy, traditional Chinese medicine decoction-free granules and applications thereof. Background technique [0002] Worldwide, malignant tumors are the second leading cause of death after heart disease. Chemotherapy is one of the core methods in the treatment of malignant tumors. Chemotherapy-induced nausea and vomiting (CINV) is a common adverse reaction, which seriously affects the quality of life of patients and the overall treatment. [0003] Current status of CINV research: [0004] 1. Classification: It is divided into five types: acute, delayed, expected, fulminant and refractory. [0005] ①Acute nausea and vomiting: generally occurs within a few minutes to several hours of administration, and reaches a peak within 5 to 6 hours after administratio...

AI Technical Summary

Problems solved by technology

Mild to moderate vomiting often leads to emotional irritability in patients. Moderate to severe vomiting will affect the patient's daily diet and nutrition, and even cause electrolyte imbalance. What's more, chemotherapy is forced to be interrupted, affecting the patient's quality of life and overall treatment

[0012] 4. Western medicine is expensive and has many side effects: Western medicine such as 5-HT 3 Although receptor antagonists and NK-1 receptor antagonists have outstanding curative effects, they have problems such as high price, large side effects, and unclear long-term adverse reactions.

In addition, although there are many types of antiemetic drugs currently used in clinical practice, there are few highly effective and multi-target antiemetic drugs

[0013] While killing tumor cells, chemotherapeutic drugs are also used as a toxic substance to damage the normal tissue cells of the body. The tissues and organs of the body are harmed and affected to varying degrees, resulting in relatively large side effects, especially likely to cause gastrointestinal dysfunction. Serious impact on patient quality of life, reducing chemotherapy compliance