Hyperlipidemia preventing and treating substance and preparation and application methods thereof
A technology of fat-soluble substances and seeds, which is applied in the field of biomedicine, can solve the problems of significant drug effects and side effects, and achieve significant and elevated levels of effects
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0022] This example is to demonstrate the effect of the substance of the present invention on the serum blood lipid level of mice. Before administering the test substance, the model was made with high-fat material. After the modeling is completed, the control substance and the substance of the present invention are administered to carry out the experiment. After the experiment, the contents of CHO, TG, HDL-C and LDL-C in the mouse serum are measured. The specific experimental methods and steps are as follows:
[0023] 1 experimental animal
[0024] Healthy adult clean-grade BALB / c male mice (license number SCXK (Beijing) 2012-0001) provided by Beijing Weitong Lihua Experimental Animal Technology Co., Ltd. were selected, and the weight range of the mice was 20.0±2.0g.
[0025] 2 Experimental design
[0026] After 1 week of adaptive feeding of BALB / c male mice, according to the weight of the mice, 45 mice were randomly divided into 3 groups, namely: a high-dose substance cont...
Embodiment 2
[0039] With 100kg of fresh rubber tree seeds as raw material, after drying and shelling, 40kg of seed kernels are prepared. Seed kernel material is heated to 80-100 ℃, then through static extrusion, the pressure is 50MPa, extruding 12kg liquid substance is the fat-soluble part of the rubber tree seed of the present invention.
[0040] 10 kg of fat-soluble substances extracted from rubber tree seeds are used as raw materials. Under vacuum conditions, the raw materials are heated to raise the temperature, and steam is passed through to carry out distillation. The gaseous molecules carried by the water vapor are condensed, and the oil floating on the condensed water is the distillation product of the fat-soluble part of the rubber tree seed. The distillation conditions are: the absolute pressure of the vacuum degree is 0.01Pa; when the raw material is heated to 160°C, water vapor is introduced, and the temperature rises to 250°C, then the temperature rise is stopped, and the temp...
Embodiment 3
[0048] With 100kg of fresh rubber tree seeds as raw material, after drying and shelling, 40kg of seed kernels are prepared. Seed kernel material is heated to 80-100 DEG C, then through dynamic screw extrusion, the screw extrusion time is about 45 seconds, extruding 15kg liquid material is the rubber tree seed fat-soluble part of the present invention.
[0049] 10 kg of fat-soluble substances extracted from rubber tree seeds are used as raw materials. Under vacuum conditions, the raw materials are heated to raise the temperature, and steam is passed through to carry out distillation. The gaseous molecules carried by the water vapor are condensed, and the oil floating on the condensed water is the distillation product of the fat-soluble part of the rubber tree seed. The distillation conditions are as follows: the absolute pressure of the vacuum degree is 0.3Pa; when the raw material is heated to 160°C, water vapor is introduced, and the temperature rises to 253°C, then the tempe...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More