A kind of high refractive index hydrophobic foldable intraocular lens material and its preparation method

A technology of intraocular lens and high refractive index, which is applied in the fields of prosthesis, tissue regeneration, medical science, etc., can solve the problems of unstable homogeneity of polymer materials, the optical performance needs to be improved, and it is difficult to recover completely, so as to reduce the cost of implant surgery. Risk and cost, ease of industrial production, and the effect of simple preparation
CN110003385BActive Publication Date: 2021-03-02SICHUAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN UNIV
Publication Date
2021-03-02

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Abstract

The invention provides a high-refractive-index hydrophobic foldable intraocular lens material, which consists of three parts of monomers formed by free radical polymerization. The first part of monomer B is a polymerizable monomer containing phenyl, specifically including B1 and B2 Two parts, wherein B1 accounts for 50%-60% of the total monomer content, B2 accounts for 30-40% of the total monomer content, and the B1 and B2 are different; the second part of the monomer C is a branched alkyl chain acrylic acid or methacrylate, accounting for 1-10% of the total monomer content; the third part monomer D is a crosslinking agent, accounting for 1.5-2.5% of the total monomer content; the total monomer content is three parts The sum of monomers B+C+D. Compared with common intraocular lens materials, the intraocular lens material provided by the present invention has higher key optical performance parameters such as transmittance and refractive index. required material properties.
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Description

technical field

[0001] The invention belongs to the field of biological materials, and in particular relates to a high-refractive-index hydrophobic foldable intraocular lens material and a preparation method thereof. Background technique

[0002] The natural lens of the normal human eye is clear and transparent, but with the increase of age, abnormalities and lesions in the body's own immune and metabolic systems, trauma caused by objective accidents, etc., the natural lens is damaged and cannot be maintained normally. A condition in which the natural lens changes from clear to cloudy is called a cataract. Because the natural lens changes from transparent to cloudy, visible light cannot pass through the natural lens and focus on the retina, which causes cataract patients to have varying degrees of visual impairment or even complete blindness. In this case, cataract patients need to be replaced with new lenses with normal performance, and intraocular lenses (Intraocular Lens...

Claims

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