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Traditional Chinese medicine composition having effect of resisting herpes viruses and preparation method and application of traditional Chinese medicine composition

A technology of anti-herpes virus, composition, applied in the field of medicine

Inactive Publication Date: 2019-07-23
苏州玉森新药开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are so many patients that it is difficult to meet the dialectical needs of most people, so it is urgent to develop Chinese patent medicines, and the traditional medicine of the motherland will benefit more people.

Method used

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  • Traditional Chinese medicine composition having effect of resisting herpes viruses and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition having effect of resisting herpes viruses and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition having effect of resisting herpes viruses and preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Earthworm 100g, Corydalis 200g, Forsythia suspensa 100g, Viola dianthus 500g, Angelica dahurica 400g, Licorice 300g. The above six flavors, crushed, immersed in 50% ethanol for 24 hours, slowly permeated, collected the percolate, recovered the ethanol under reduced pressure and concentrated to a clear paste with a relative density of 1.01 (60℃), refrigerated overnight; take the supernatant Continue to concentrate to a thick paste with a relative density of about 1.15 (60°C). Add 0.6% poloxamer and purified water to the precipitate to dissolve and filter to obtain the filtrate. Take purified water, add 100 g of glycerin and 10 g of carbomer, and stir until swelling to obtain a gel. Take the thick extract of the extract and the filtrate into the gel matrix, stir well, add triethanolamine to adjust the pH to 6.0-6.5, add purified water, stir well, and dispense to obtain.

Embodiment 2

[0032] Dilong 150g, Corydalis 200g, Forsythia 150g, Viola vulgaris 150g, Angelica dahurica 100g, Licorice 50g. The above six flavors, 10 mesh, crushed, use 60% ethanol as a solvent, after immersing for 24 hours, slowly percolate at a rate of 5-10ml per minute, collect the percolate, recover the ethanol under reduced pressure and concentrate to a relative density of 1.01-1.04 ( 60℃) clear paste, refrigerate overnight, take the supernatant and continue to concentrate to a thick paste with a relative density of about 1.22-1.30 (60℃). Add 1.2% poloxamer and 17% purified water to the precipitate to dissolve and filter to obtain the filtrate. Take 400 g of purified water, add 100 g of glycerin, 20 g of carbomer, and 3 g of ethyl paraben (dissolved in ethanol), and stir to swell to obtain a gel matrix. Take the thick extract of the extract and the filtrate into the gel matrix, stir well, add triethanolamine to adjust the pH to 6.0-6.5, add purified water, stir well, and dispense to o...

Embodiment 3

[0034] Earthworm 300g, Corydalis 400g, Forsythia suspensa 300g, Viola odoratum 300g, Angelica dahurica 250g, Licorice 200g. The above six flavors, pulverized with 16 meshes, used 80% ethanol as a solvent, soaked, slowly permeated at a speed of 5-10ml per minute, collected the percolate, recovered the ethanol under reduced pressure and concentrated to a relative density of 1.01-1.03 (60℃) The clearing paste, refrigerate overnight, take the supernatant and continue to concentrate to a thick paste with a relative density of about 1.25-1.30 (60℃). Add 1.8% poloxamer and purified water to the precipitate to dissolve it and filter to obtain the filtrate. Take 400 g of purified water, add 100 g of glycerin and 30 g of carbomer, and stir until swelling to obtain a gel matrix. Take the thick extract of the extract and the filtrate into the gel matrix, stir evenly, add triethanolamine to adjust the pH to 6.5-7.0, add purified water, stir evenly, and dispense to obtain.

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PUM

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine composition having effect of resisting herpes viruses and a preparation method andapplication of the traditional Chinese medicine composition. The composition consists of the following traditional Chinese medicine raw materials of 1-5 parts by mass of earthworms, 2-6 parts by massof rhizoma corydalis, 1-5 parts by mass of fructus forsythiae, 1-5 parts by mass of herba violae, 1-4 parts by mass of radix angelicae dahuricae and 1-3 parts by mass of licorice roots. The inventionfurther discloses a preparation method of a gel preparation of the composition and application of the composition.

Description

Technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a traditional Chinese medicine composition with anti-herpes virus and a preparation method and application. Background technique [0002] Herpes refers to diseases caused by viruses of the herpesvirus family (HHV). HHV is a group of medium-sized enveloped DNA viruses that can cause a variety of human diseases, and can lie in the body for a long time, and re-infect under certain conditions. Common clinical diseases include herpes zoster, herpes simplex, and genital herpes. Many of them can invade multiple organs of the human body, and the disease can occur at any age. The characteristics of herpes virus infection, in addition to pro-neuropathic, long-term incubation, the main clinical symptoms are skin herpes, accompanied by severe pain, and even ulcer infection, fever, invasion of other organs, etc. [0003] Western medicine generally gives symptomatic and antiviral treat...

Claims

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Application Information

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IPC IPC(8): A61K36/86A61K9/06A61K47/32A61K47/10A61K47/18A61P31/22A61K35/62
CPCA61K9/0014A61K9/06A61K35/62A61K36/232A61K36/484A61K36/634A61K36/66A61K36/86A61K47/10A61K47/18A61K47/32A61K2236/333A61K2236/51A61K2300/00
Inventor 玄振玉郭飞龙李亦秀邵一丹丁美琳张凡陆琪陆赛卫
Owner 苏州玉森新药开发有限公司
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