Auto-developing degradable vascular stent
A vascular stent and auto-imaging technology, which is applied in the field of auto-degradable vascular stents, can solve the problems of weak adhesion between the imaging layer and the stent, thrombosis, secondary injury to patients, etc. Load time, effect of reducing foreign body reaction
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Embodiment 1
[0018] Example 1: Inject the 200,000 Da L-polylactic acid macromolecule in molten state into the mould, cool and demould to obtain the blank of the stent body, clean the blank 3 times with alcohol, and then place the blank on In the gelatin aqueous solution, soak for 10 minutes, dry, make the surface of the blank adhere to a layer of gelatin, and make the stent body;
[0019] (b) Add L-polylactic acid to chloroform, stir evenly, add diatrizoate meglumine to the solution system to prepare a developing mixed solution, and spray the developing mixed solution on the preparation prepared in the above step (a) by ultrasonic atomization The support bar of the support body and the surface of the support ring away from the center of the support body are prepared as a developing layer, and then the support body is placed in the gelatin aqueous solution of the above step (a) to soak for 10 minutes and dried;
[0020] (c) Put the above-mentioned stent body on the stainless steel tube, fix...
Embodiment 2
[0022] Embodiment 2: Inject the L-polylactic acid macromolecule in the molten state into the mould, cool, and demould to obtain the blank of the stent body, clean the blank 3 times with alcohol, and then place the blank in an aqueous gelatin solution, Soak for 20min, dry, make the surface of the blank adhere to a layer of gelatin, and make the bracket body;
[0023] (b) adding L-polylactic acid to chloroform, stirring evenly, adding a developer to the solution system to prepare a developing mixed solution, and depositing the developing mixed solution on the stent body prepared in the above step (a) by plasma vapor deposition The surface of the support bar and the support ring away from the center of the bracket body is prepared as a developing layer, and then the bracket body is placed in the gelatin aqueous solution of the above step (a) to soak for 10 minutes and dried;
[0024] (c) Put the above-mentioned support body on the stainless steel tube, and fix the support body on...
Embodiment 3
[0026] Embodiment 3: Inject the L-polylactic acid macromolecule in molten state into the mould, cool, demould to obtain the blank of the stent body, clean the blank 3 times with alcohol, then place the blank in the gelatin aqueous solution, Soak for 10min, dry, make the surface of the blank adhere to a layer of gelatin, and make the bracket body;
[0027] (b) Add L-polylactic acid to the chloroform solution, stir evenly, add diatrizoate meglumine to the solution system to prepare a developing mixed solution, and prepare the developing mixed solution in the above step (a) by ultrasonic atomization and spraying The surface of the support bar of the stent body and the support ring away from the center of the stent body is prepared as a developing layer, and then the stent body is placed in the gelatin aqueous solution of the above step (a) to soak for 20min and dried;
[0028] (c) Put the above-mentioned bracket body on the stainless steel tube, fix the bracket body on the stainl...
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