A kind of degradable magnesium alloy and preparation method thereof

A magnesium alloy, an inevitable technology, applied in the field of degradable magnesium alloy and its preparation, can solve the problems of poor mechanical properties, hard and brittle, slow, etc., to reduce the probability of infection and inflammation, improve osteoporosis symptoms, overcome emphysema Effect

Active Publication Date: 2020-12-15
BEIJING WANJIE MEDICAL DEVICE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

As an implant, bioceramics can meet the general requirements of artificial bone. Its advantages are good biocompatibility, but its disadvantages are poor mechanical properties, hard and brittle, easy to break and slow degradation and absorption, and the elastic modulus does not match the stress shielding of bone. obvious

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  • A kind of degradable magnesium alloy and preparation method thereof

Examples

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Embodiment 1

[0026] What described in embodiment 1 of the present invention is a kind of degradable magnesium alloy, and this magnesium alloy comprises the component of following mass percentage:

[0027] Zn, 1-4%; Ca, 0.5-4%; Sr, 0.1-0.9%; Ga, 0.3-2%; the rest is Mg element and unavoidable impurities.

[0028] First, as a new type of orthopedic material, magnesium metal has a modulus and density closer to bone tissue, and its strength and plasticity are far superior to current bioceramics, calcium sulfate, plastics and other absorbable materials. Second, good biocompatibility: Magnesium is an essential element for normal life activities and metabolic processes of the human body. The total magnesium content of a normal adult body is about 25g, of which 60%-65% exists in bones and teeth, and 27% is distributed in in soft tissue. Magnesium affects a variety of biological functions of cells, such as affecting the transport of potassium ions and calcium ions, regulating signal transmission; p...

Embodiment 2

[0031]A degradable magnesium alloy, the only difference from Example 1 is that it includes the following components in mass percentage: Zn, 1-2%; Ca, 0.5-4%; Sr, 0.1-0.9%; Ga, 0.3-2% %; the rest is Mg element and unavoidable impurities.

Embodiment 3

[0033] A degradable magnesium alloy, the only difference from Example 1 is that it includes the following components in mass percentage: Zn, 2-3%; Ca, 0.5-4%; Sr, 0.1-0.9%; Ga, 0.3-2% %; the rest is Mg element and unavoidable impurities.

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Abstract

The invention discloses a degradable magnesium alloy which is prepared from the following components in percent by mass: 1-4% of Zn, 0.5-4% of Ca, 0.1-0.9% of Sr, 0.3-2% of Ga and the balance Mg and inevitable impurities. The invention also discloses a preparation method of the degradable magnesium alloy. The preparation method comprises the following steps: weighing Zn, Ca, Sr, Ga and Mg in percent by mass, separately; putting Sr and Ga in a vacuum smelting furnace, vacuumizing the vacuum smelting furnace to 10<-3> Pa and heating the vacuum smelting furnace to 350 DEG C; introducing protective gas, heating the vacuum smelting furnace to 950 DEG C, and electromagnetically stirring the mixture for 5-10 min; cooling the vacuum smelting furnace to 450 DEG C, adding Mg, heating the vacuum smelting furnace to 730+ / -5 DEG C, and insulating and stirring the mixture for 5-30 min to mix the metals uniformly; successively adding Zn and Ca, insulating the mixture for 5-30 min and leaving the mixture to stand for 10-15 min; and pouring a molten alloy into a corresponding mold, and insulating the mold for 24 hours at 250 DEG C.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a degradable magnesium alloy and a preparation method thereof. Background technique [0002] At present, in soft tissue and anterior cruciate ligament reconstruction operations at home and abroad, bone tunnels need to be drilled out of positioning considerations. According to different constitutions, patients generally heal the bone tract naturally within 4-6 months after operation. However, due to the repeated scouring and stimulation of human tissue fluid and the wiper effect of positioning sutures, there is a certain probability of inflammation in the bone tract, delaying healing and even causing the failure of ligament positioning surgery. This problem has attracted widespread attention in the medical field, but there is no effective solution. The most direct way to solve this problem is to fill the wound with absorbable bone repair materials. Currently, more absor...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C22C23/00C22C23/04C22C1/02A61L27/04A61L27/54A61L27/58A61L31/02A61L31/14A61L31/16
CPCA61L27/047A61L27/54A61L27/58A61L31/022A61L31/148A61L31/16A61L2300/404A61L2430/02C22C1/02C22C23/00C22C23/04
Inventor 张梅董喜华孙雪莲刁冰寒陈书香史丰田
Owner BEIJING WANJIE MEDICAL DEVICE CO LTD
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