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Mouthwash for treating and preventing oral ulcer and preparation method thereof
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A mouthwash and deionized water technology, applied in the field of mouthwash, can solve problems such as insoluble in water, bitter taste, etc., and achieve the effect of preventing periodontitis, relieving inflammation, and regulating the balance of oral flora
Inactive Publication Date: 2019-09-20
JIANGXI SHANXING BIOTECHNOLOGY CO LTD
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[0031] The preparation method comprises the following steps:
[0032] (1) Dissolve 2g of lactoferrin in 50ml of acetic acidbuffer solution of pH5~6, control the stirring speed to 200-500r / min and stir for 1h; dissolve 1.2g of curcumin and 0.4g of osthole in 50ml of ethanol without water , stirring for 0.5-1h;
[0033] (2) Mix the two solutions in step (1), and add 200ml of deionized water.
[0034] (3) Add the solution obtained in step (2) into a 500ML three-necked flask, add 5g of petroleumether and 3g of diatomaceous earth, heat to 60-80°C for reflux extraction for 30-50min; filter after reflux, and recover petroleumether, Discard the filter residue.
[0035](4) Repeat the filtering step in step (3), add 3g o...
Embodiment 2
[0040] The formula is: lactoferrin 4g, curcumin 0.5g, osthole 0.2g, chitosan 0.01g, lysozyme 0.1g, chitin 0.1g, chitooligosaccharide 0.1g, Radix Panax notoginseng extract 2g, honeysuckle 2g, mulberry leaves 2g, sorbic acid 0.6g, deionized water 5000ml, peppermint oil 0.01g.
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Abstract
The invention provides a mouthwash for treating and preventing oral ulcer and a preparation method thereof. The mouthwash is composed of, by weight, 4-10g of lactoferrin, 0.5-2.0g of curcumin, 0.2-0.7g of cnidiumlactone, 0.01-0.3g of chitosan, 0.1-3g of lysozyme, 0.1-3g of chitin, 0.1-2g of chitosanoligosaccharide, 2-8g of gynura divaricata extract, 2-8g of flos lonicerae, 2-8g of folium mori, 0.6-1.8g of sorbic acid, 500-800ml of deionized water and 0.01-0.3g of mint oil. Lactoferrin in the formula not only serves as a carrier but also has excellent antibacterial effect, especially has remarkable effect on the oral ulcer due to mixing with curcumin, cnidiumlactone, lysozyme and chitin. The mouthwash can regulate oral flora balance, quickly relieve inflammation, inhibit bacteria for a long time and freshen mouth smell and has good anti-inflammatory, analgesic and hemostatic functions.
Description
technical field [0001] The invention belongs to the technical field of mouthwash, and in particular relates to a mouthwash for treating and preventing oral ulcers and a preparation method thereof. Background technique [0002] In my country, 90% of people are troubled by oral problems to varying degrees. According to the latest "China National Oral Health Survey Report", the highest frequency of oral problems is oral odor and bleeding gums. The proportion of these two symptoms is 65.8%. Secondly, the proportion of oral ulcers is more than half, reaching Swelling accounted for 53.0%, becoming the third most troubled oral symptoms, followed by swelling accounting for 41.1% and dry mouth accounting for 28.4%. One of the main causes of oral problems is that the mouth cannot be cleaned in time after meals. The food residues left in the gaps of the teeth become a breeding ground for bacteria. At the same time, there are about 600 kinds of microorganisms living in our mouth, inclu...
Claims
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