Unlock instant, AI-driven research and patent intelligence for your innovation.

Ceramide compound and preparation method thereof

A technology of ceramide and compound, applied in the field of ceramide compound and its preparation, can solve the problems of limited addition of ceramide and poor stability, and achieve the effects of improving efficacy, good stability and reducing production cost

Inactive Publication Date: 2019-09-20
ZHONGSHAN ZHONGYAN COSMETIC CO LTD
View PDF6 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to solve the problems of limited ceramide addition and poor stability in existing cosmetics, the present invention provides a relatively high ceramide content, containing one or more ceramides, which has excellent efficacy, stability and water dispersion Sexual ceramide complex and preparation method thereof

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Ceramide compound and preparation method thereof
  • Ceramide compound and preparation method thereof
  • Ceramide compound and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A ceramide complex comprising the following components by mass percentage:

[0029] components Mass percentage (%) dipropylene glycol 20 glycerin 10 hydrogenated lecithin 4.5 Lysolecithin 0.1 Ceramide 2 0.7 Ceramide 3 0.3 cholesterol 0.5 Disodium EDTA 0.1 1,2-pentanediol 5 water margin

[0030] The sum of each component is a percentage.

Embodiment 2

[0032] A ceramide complex comprising the following components by mass percentage:

[0033]

[0034]

[0035] The sum of each component is 100%, and the water is ultrapure water.

[0036] The preparation method of above-mentioned embodiment 1 and embodiment 2, operates as follows:

[0037] 1. Mix ceramide 2, ceramide 3, cholesterol and glycerin evenly in proportion, and heat and melt on an electric furnace. Ceramide and cholesterol have the best dispersion effect in glycerin.

[0038] 2. Mix the hydrogenated lecithin and dipropylene glycol according to the proportion and melt them in a water bath at 90°C. Hydrogenated lecithin has the best dispersion effect in dipropylene glycol. It can be melted and dispersed evenly when heated to 90°C. Avoid excessive heating temperature that will cause the material to turn yellow and affect the application of the compound in transparent skin care products.

[0039] 3. Pour the molten mixture of hydrogenated lecithin and dipropylene ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a ceramide compound, which comprises the following components in percentage by mass: 10-40% of polyol, 1-8% of an emulsifier, 0.5-5% of ceramide, 0.1-3% of cholesterol, 0.05-2% of an auxiliary agent and 50-70% of water; and the sum of all components is 100%, wherein the polyol is formed by mixing 70-95wt.% of humectant polyol with a humectant effect and 5-30wt.% of anticorrosive polyol with an anticorrosive effect; and the emulsifier is formed by mixing 85-99wt.% of alcohol-soluble emulsifier soluble in polyol and 1-15wt.% of water-soluble emulsifier soluble in water. The invention further provides a preparation method of the ceramide compound. The ceramide compound has excellent efficacy, stability, biocompatibility and water dispersibility, and can be applied to cosmetics of multiple dosage forms.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a ceramide complex and a preparation method thereof. Background technique [0002] Ceramide is a class of phospholipids with ceramide as the backbone, mainly including ceramide phosphorylcholine and ceramide phosphoethanolamine. Phospholipids are the main components of cell membranes. 40% to 50% of the sebum in the stratum corneum is composed of ceramide. It is the main part of the intercellular matrix and plays an important role in maintaining the water balance of the stratum corneum. Ceramide has a strong ability to associate water molecules, and it maintains skin moisture by forming a network structure in the stratum corneum. However, as an oil-soluble substance with a high melting point, it is difficult to directly add ceramide to cosmetics, especially water-based products, and the amount of addition is very limited, and it is easy to precipitate and affect the stability of the over...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/68A61K8/63A61K8/34A61K8/55A61Q19/00A61Q19/02
CPCA61K8/345A61K8/553A61K8/63A61K8/68A61Q19/00A61Q19/02
Inventor 莫美玲
Owner ZHONGSHAN ZHONGYAN COSMETIC CO LTD