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Anti-febrile gel film patch and preparation method and application thereof

The technology of a gel film and a gel layer is applied in the field of antipyretic gel film stickers and their preparation, and achieves the effects of being suitable for industrial production, comfortable and cool for sticking, and efficient transdermal absorption rate

Pending Publication Date: 2019-10-08
武汉兴嘉业堂医疗科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, there is currently no product on the market that combines cold compress therapy, aromatherapy, TTS / TDDS theory and acupoint application

Method used

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  • Anti-febrile gel film patch and preparation method and application thereof
  • Anti-febrile gel film patch and preparation method and application thereof
  • Anti-febrile gel film patch and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] In parts by weight, weigh 15 parts of glycerin and 10 parts of kaolin and mix them, stir at a speed of 250r / min until the kaolin is fully dispersed in glycerin to obtain a kaolin-glycerin suspension; Add 2.5 parts of hydrogel resin powder, 2.5 parts of PVPP, 0.05 part of EDTA-2Na, 0.25 part of aluminum chloride, 0.1 part of deoxycholic acid, and 0.2 part of indirubin to the liquid in sequence, and stir at a speed of 250r / min until the material Thoroughly mix evenly to obtain the matrix;

[0057] In parts by weight, 5 parts of PVP-K120 and 0.5 parts of tartaric acid were sequentially added to 56.65 parts of purified water, and stirred at a speed of 250 r / min until fully mixed to obtain an aqueous phase;

[0058] In parts by weight, 2.5 parts of propylene glycol, 2.5 parts of glycerin, 2.5 parts of oily azone, 1.5 parts of eucalyptus oil, 0.005 parts of flavoring agent, 1.5 parts of thymol, and 0.3 parts of Tween 80 were added successively to 2.5 parts of menthol , stirr...

Embodiment 2

[0063] In parts by weight, weigh 12 parts of glycerin and 6 parts of kaolin and mix them, stir at a speed of 250r / min until the kaolin is fully dispersed in glycerin to obtain a kaolin-glycerin suspension; Add 1.5 parts of hydrogel resin powder, 2.0 parts of PVPP, 0.03 parts of EDTA-2Na, 0.3 parts of starch aluminum, 0.2 parts of deoxycholic acid, and 0.5 parts of indirubin to the liquid in sequence, and stir at a speed of 250 r / min until the materials are fully Mix evenly to obtain the matrix;

[0064] In parts by weight, 3.5 parts of PVP-K120 and 0.2 parts of tartaric acid were sequentially added to 69.94 parts of purified water, and stirred at a speed of 220 r / min until fully mixed to obtain a water phase;

[0065] In parts by weight, sequentially add 1.5 parts of propylene glycol, 1.5 parts of glycerin, 1.5 parts of oily azone, 1 part of eucalyptus oil, 0.003 parts of flavoring agent, 1 part of thymol, and 0.2 parts of Tween 80 into 1.5 parts of menthol , stirring at a ra...

Embodiment 3

[0069]In parts by weight, weigh 13 parts of glycerin and 12 parts of kaolin and mix them, and stir at a speed of 250r / min until the kaolin is fully dispersed in glycerin to obtain a kaolin-glycerin suspension; Add 4.0 parts of hydrogel resin powder, 4.5 parts of PVPP, 0.08 parts of EDTA-2Na, 0.2 parts of aluminum chloride, 0.5 parts of deoxycholic acid, and 0.3 parts of indirubin to the liquid in sequence, and stir at a speed of 250r / min until the material Thoroughly mix evenly to obtain the matrix;

[0070] In parts by weight, 8 parts of PVP-K120 and 0.8 parts of tartaric acid were sequentially added to 52 parts of purified water, and stirred at a speed of 260 r / min until fully mixed to obtain an aqueous phase;

[0071] In parts by weight, sequentially add 4.5 parts of propylene glycol, 4.5 parts of glycerin, 4.5 parts of oily azone, 2 parts of eucalyptus oil, 0.008 parts of flavoring agent, 2 parts of thymol, and 0.4 parts of Tween 80 into 4.0 parts of menthol , stirring at...

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Abstract

The invention provides an anti-febrile gel film patch. The anti-febrile gel film patch comprises a gel layer which is prepared in the mode that a non-woven fabric is coated with a gel material; and the gel material comprises the following raw materials in parts by mass: 1-5 parts of hydrogel resin powder, 1-5 parts of PVPP, 0.01-0.1 part of EDTA-2Na, 0.1-0.5 part of a cross-linking agent, 1-10 parts of PVP, 0.1-1 part of tartaric acid, 1-2 parts of saikoside, 1-2 parts of artemisinin, 0.1-0.5 part of deoxycholic acid, 0.1-1 part of indirubin, 1-5 parts of earthworm fluid, 1-10 parts of raw ginger juice, 0.5-2.5 parts of thymol crystals, 0.5-2 parts of eucalyptus oil, 1-5 parts of menthol, 1-5 parts of azone, 0.1-0.5 part of Tween, 1-5 parts of propylene glycol, 10-20 parts of glycerinum, 5-15 parts of kaolin, 0.001-0.005 part of a flavor blending agent, and 50-80 parts of purified water. The prepared anti-febrile gel film patch can stimulate the healing balancing function of human organisms, the inherent disease-resisting and self-regulation and repairing capacity of the organisms is improved, and the anti-febrile, analgesic and anti-inflammatory effects are achieved.

Description

technical field [0001] The invention relates to the technical field of medical application, in particular to an antipyretic gel film and its preparation method and application. Background technique [0002] Fever refers to the direct action of pyrogens on the thermoregulation center, the dysfunction of the body temperature center, or excessive heat production and reduced heat dissipation caused by various reasons, resulting in an increase in body temperature beyond the normal range. [0003] Commonly used physical cooling methods include alcohol wiping method, ice compress method, sticking antipyretic stickers, etc. Although the alcohol wiping method has obvious cooling effect, it is highly irritating to the skin and is likely to cause damage to the health of infants and young children; the sustainable cooling method of ice compress method Limited time, insufficient fit to the affected area, and insufficient comfort make it difficult to use on infants and children; antipyret...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K36/9068A61K47/32A61P29/00A61K31/045A61K31/05A61K31/366A61K31/404A61K31/575A61K31/7048A61K35/62
CPCA61K9/7023A61K47/32A61K31/7048A61K31/366A61K31/575A61K31/404A61K35/62A61K36/9068A61K31/05A61K36/61A61K31/045A61P29/00A61K2300/00
Inventor 樊平
Owner 武汉兴嘉业堂医疗科技发展有限公司
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