Chinese medicinal material extract with function of reducing weight and preparation method of Chinese medicinal material extract

A technology for extracts and Chinese medicinal materials, which is applied in the field of Chinese medicinal material extracts with weight loss effect and its preparation field, can solve problems such as no weight loss effect found, and achieve the effects of improving adipose tissue hypertrophy, low cost, and reducing body fat.

Inactive Publication Date: 2019-10-08
云南省中医中药研究院
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  • Abstract
  • Description
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  • Application Information

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  • Chinese medicinal material extract with function of reducing weight and preparation method of Chinese medicinal material extract
  • Chinese medicinal material extract with function of reducing weight and preparation method of Chinese medicinal material extract

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preparation example Construction

[0031] A method for preparing a Chinese medicinal material extract with weight loss effect, comprising the following steps: Step 1, raw material selection; Step 2, raw material pretreatment; Step 3, raw material roasting; Step 4, raw material kneading; Step 5, raw material drying; Step 6, extract preparation;

[0032] Wherein in above-mentioned step 1, select the cauline leaf on the twig of green thorn point and appropriate amount of purified water for subsequent use;

[0033] Wherein in the above step 2, remove floating ash, insect eggs or yellow leaves from the stems and leaves, clean them with warm water at 30-45°C and dry them for later use;

[0034] Wherein in the above step three, the cleaned stems and leaves are roasted with a frying machine until the stems and leaves are heated and curled. The roasting temperature of the roasting machine is 250-300 ° C, and the roasting speed is 40-50 rpm , the frying time is 5-8 minutes;

[0035] Among them, in the above step 4, the...

Embodiment 1

[0043] After feeding the mice with the green thorn point extract for 1 week, compared with the model group, the weight of the mice in the administration group was stable and did not increase significantly, and the weight of the mice was lower than that of the model group, P<0.05. Compared with the positive group, the body weight of the administration group was higher than that of the positive group, and there was a concentration-effect relationship, and the difference between the body weight of the high-dose group and the positive group was small. The results showed that the extract of the green thorn tip could effectively reduce the body weight of obese mice.

Embodiment 2

[0045] After feeding the mice with the extract of green thorns for 2 weeks, compared with the model group, the body fat content of the high-dose group was significantly reduced, P<0.05, and after feeding the mice with the extract of green thorns for 3 weeks, P<0.01. The body fat growth rate of the mice in the administration group was lower than that in the model group, and the results showed that the extract of the green thorns can reduce the body fat content of the obese mice induced by high-fat diet.

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Abstract

The invention discloses a Chinese medicinal material extract with the function of reducing weight and a preparation method of the Chinese medicinal material extract. The Chinese medicinal material extract raw material is prepared from stems and leaves of twigs of prinsepia utilis royle. The preparation method includes the steps of step one, raw material selection; step two, pretreatment of raw materials; step three, baking of the raw materials; step four, raw material rolling; step five, raw material drying; and step six, extract preparation. According to the Chinese medicinal material extractwith the function of reducing weight and the preparation method of the Chinese medicinal material extract, preparation of the extract from the prinsepia utilis royle is simple and easy to carry out,and the cost is low. According to a C57BL/6J mouse model experiment, the weights of obese mice can be effectively reduced, the body fat content of the obese mice induced by high-fat diet can be reduced, the lipid level of the obese mice induced by the high-fat diet can be effectively regulated, and LPL and PL levels in serum of the obese mice can be effectively regulated. With the effect of significant weight loss, the Chinese medicinal material extract can reduce fat tissue hypertrophy, is used as raw materials of weight-loss drugs, health products or food to help obese people lose weight andreduce body fat.

Description

technical field [0001] The invention relates to the technical field of biomedicine and general health industry, in particular to a Chinese medicinal material extract with weight loss effect and a preparation method thereof. Background technique [0002] With the change of diet structure and the improvement of living standards, the number of obese people is increasing. According to the World Health Organization survey, in 2016, more than 1.9 billion adults in the world were overweight, and more than 650 million people were obese. At least 2.8 million deaths each year can be attributed to being overweight or obese. Once considered a problem in high-income countries, obesity is now widespread in low- and middle-income countries as well. Obesity not only affects people's appearance and image, but is often accompanied by abnormal glucose and lipid metabolism. It also increases the risk of diabetes, hypertension, coronary heart disease, hyperlipidemia and other epidemic diseases....

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P3/04A61K135/00A61K127/00
CPCA61K36/73A61K2236/331A61P3/04
Inventor 李艳萍夏海梅刘因华何鹏飞张菊王胤骁赵远
Owner 云南省中医中药研究院
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