The present invention relates to a formula of weight-loss medicine, and the raw materials in the formula are respectively composed by weight percentage: Astragalus 5-15%, Angelica 1-5%, Poria 1-10%, Atractylodes macrocephala 5-15%, Alisma 3-9 %, Plantago 2‑3%, Amomum 1‑5%, Yam 11‑19%, Dogwood 5‑7%, Morinda officinalis 3‑5%, Cuscuta 3‑5%, Cinnamon 1‑5%, Rehmannia glutinosa Huang 5‑10%, Safflower 1‑1.5%, Epimedium 4‑5%, Junchen 2‑4%, Radix Polygoni Multiflori 0.4‑0.6%, Fructus Rosa 1‑2%, Polygonatum 2‑4%, Raw Hawthorn 1‑3%, the slimming drug of the present invention has the effect of stably lowering blood pressure without rebounding and stabilizing blood pressure for a long time. It does not need long-term medication, has no drug resistance, is safe and has no side effects, and is suitable for a wide range of people. It is a caring medicine for ordinary people.