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A kind of synergistic antioxidant oral care composition and application thereof

An oral care and composition technology, applied in the field of oral care, can solve problems such as tooth loss, and achieve the effect of improving antioxidant capacity

Active Publication Date: 2022-07-15
HAWLEY & HAZEL BVI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, chronic infection and inflammation may lead to subsequent tooth loss

Method used

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  • A kind of synergistic antioxidant oral care composition and application thereof
  • A kind of synergistic antioxidant oral care composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] A toothpaste composition, comprising the following raw materials by weight:

[0109] Element added amount stannous fluoride 0.10% tea polyphenols 0.01% Magnolol Extract 0.50% Sorbitol 66% silica 16% SLS 2.20% essence 1.05% saccharin 0.15% Deionized water Add to 100%

[0110] Among them, the ratio of EGCg in the tea polyphenols is 60%; the weight ratio of honokiol and honokiol in the honokiol extract is 5:5.

[0111] Antioxidant test:

[0112] 1. Experimental Materials

[0113] 1.1. Reagents: ethanol, DPPH (1,1-diphenyl-2-trinitrophenylhydrazine), the above toothpaste

[0114] 1.2. Instrument: Shimadzu UV-1780

[0115] 2. Solution Preparation

[0116] 2.1. DPPH solution: Weigh 7.9 mg of DPPH into a 20 ml volumetric flask, dissolve in ethanol and dilute to the mark. It was then diluted with ethanol to 100 μmol / l.

[0117] 2.2. To prepare toothpaste solution: Weigh 2 g of toothpaste shown in the t...

Embodiment 2- Embodiment 3

[0125] A toothpaste composition, comprising the following raw materials by weight:

[0126] Ingredient% Example 2 Example 3 Sorbitol 70 70 CMC-Na 0.5 0.5 Tetrasodium pyrophosphate 0.5 0.5 Sodium Saccharin 0.15 0.15 sodium fluoride 0.167 0.167 stannous fluoride 0.1 0.1 silica 16 16 tea extract 0.01 0.01 essence 1.05 1.05 SLS 2.2 2.2 Magnolia Bark Extract / 0.3 water margin margin

[0127] As in Example 2 and Example 3, Example 3 added Magnolia officinalis extract on the basis of Example 2.

[0128] The above formula was placed at 40°C for 3 months, and the EGCg content in the formula was detected.

[0129] EGCg content (ppm) Example 2 Example 3 start 27.3 30 after aging 0 12.6

[0130] It can be seen from the above examples that in addition to synergistic anti-oxidation, Magnolia officinalis extract can improve the stability of tea polyphenols...

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Abstract

The invention discloses a synergistic antioxidant oral care composition. The composition comprises tea polyphenols and Magnolia officinalis extract and an orally acceptable carrier, wherein the weight ratio of tea polyphenols and Magnolia officinalis extract is 100 :1‑1:100. The composition of the present invention greatly improves the antioxidant capacity through the synergistic action of the components tea polyphenols and Magnolia officinalis extract.

Description

technical field [0001] The invention relates to the technical field of oral care, in particular to a synergistic antioxidant oral care composition and application thereof. Background technique [0002] Human periodontal disease is an inflammatory disorder that is the result of a complex interaction between periodontal disease pathogens and the host immune response. It is generally accepted that there are two related aspects to the progression of periodontal disease, the first is the activation of the host immune system and the second is the generation of oxygen free radicals and their associated metabolites. Increased production of oxygen free radicals can contribute to oxidative stress, which is thought to be involved in periodontal disease. [0003] Gingivitis is inflammation or infection of the gums and alveolar bone that support the teeth. Gingivitis is generally believed to be caused by oral bacteria, particularly those initiated in plaque formation, and toxins produc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61Q11/00
CPCA61K8/9789A61Q11/00A61K2800/5922A61K2800/522
Inventor 陈晓斌周艺
Owner HAWLEY & HAZEL BVI