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A kind of preparation method of gardenia fermented bacterium

A technology for fermenting bacteria and fermented soy bean, which is applied in the field of preparation of two-way solid fermentation products of traditional Chinese medicine, can solve the problems of reduced enzyme activity and destruction of β-glucosidase, etc., so as to achieve process and quality improvement, change dosage form, and improve antidepressant effect. Effect

Active Publication Date: 2022-03-04
HEILONGJIANG ACAD OF TCM
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  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The invention provides a method for preparing fermented fungus of fermented fermented jasmine jasmine, which is different from the traditional process, and solves the problem that β-glucosidase is largely destroyed and the enzyme activity is greatly reduced in the decoction process of the traditional process

Method used

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  • A kind of preparation method of gardenia fermented bacterium

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specific Embodiment approach 1

[0014] Specific embodiment one: the preparation method of fermented fungus of gardenia jasminoides in this embodiment is characterized in that the preparation method is carried out according to the following steps:

[0015] 1. Add water to decoct Gardenia, Artemisia annua, and mulberry leaves, then soak soybeans with the decoction liquid, and then sterilize the soybeans at high temperature after absorbing the decoction liquid to expand; to obtain the fermentation substrate;

[0016] 2. The fermentation substrate prepared in step 1 is inoculated with microorganisms containing β-glucosidase and protease, mixed and fermented, and the fermented bacteria of Gardenia jasminum is obtained;

[0017] Among them, the dry weight ratio of soybean, gardenia, Artemisia annua and mulberry leaves is 100:(20-40):(5-10):(5-10).

specific Embodiment approach 2

[0018] Specific embodiment 2: The difference between this embodiment and specific embodiment 1 is: the preparation method, which is characterized in that the microorganisms described in step 2 are Bacillus subtilis and / or Amanita agaricus. Others are the same as the first embodiment.

specific Embodiment approach 3

[0019] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is: in step 2, bacillus subtilis (10 5 ~10 6 CFU / ml) and / or Pyrrhimus umbilifolii (10 5 ~10 6 spores / ml) inoculum volume is 20-40ml / kg. Others are the same as the first or second embodiment.

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Abstract

The invention discloses a preparation method of gardenia fermented fungus, which relates to a preparation method of a two-way solid fermentation product of traditional Chinese medicine. The invention provides a method for preparing fermented fungus of fermented fermented fermented fermented jasmine jasmine. The method is different from the traditional process, and solves the problem that β-glucosidase is largely destroyed and the enzyme activity is greatly reduced in the decoction process of the traditional process. Preparation method: 1. Add water to decoct gardenia, Artemisia annua, and mulberry leaves, then soak soybeans with the decoction liquid, and sterilize the soybeans after absorbing the decoction liquid to expand to obtain a fermentation substrate; 2. Fermentation substrate prepared in step 1 The microorganisms containing β-glucosidase and protease are inoculated, mixed and fermented, and the fermented bacterial mass of gardenia jasmine is obtained. The traditional gardenia decoction is a decoction, but the fermented fungus of gardenia prepared by the method of the present invention is solid, which not only has a large difference in the preparation process, but also changes the dosage form of the medicine, reduces the dosage, and is more convenient to carry.

Description

technical field [0001] The invention relates to a preparation method of a bidirectional solid fermentation product of traditional Chinese medicine. Background technique [0002] Zhiziqi Decoction is a classic prescription in Zhang Zhongjing's "Treatise on Febrile Diseases". It is composed of gardenia and light soybean meal. According to reports, Zhizichi Decoction can increase the content of dopamine and serotonin in the blood of depression model rats, showing obvious antidepressant effect. The original recipe records that the decoction method of gardenia soup is "two flavors of gardenia and light fermented soybeans, four liters of water, first boil gardenia, get two and a half liters, then add soy sauce, boil for one and a half liters, remove the water... ...", some scholars conducted research on this decocting method, and the results showed that decocting gardenia first to dissolve geniposide, and then being hydrolyzed into genipin by β-glucosidase in tempeh, and then com...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/744A61K36/48A61P25/24
CPCA61K36/744A61K36/282A61K36/605A61K36/48A61P25/24A61K2236/19A61K2300/00
Inventor 王伟明陈丽艳孙银玲曹阳方自若
Owner HEILONGJIANG ACAD OF TCM
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