Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Electrochemical chiral sensor constructed by reduced graphene composite material

A composite material, graphene technology, applied in the direction of material electrochemical variables, scientific instruments, analytical materials, etc., can solve problems such as ineffectiveness and toxicity, and achieve the effect of wide electrochemical window, low cost, and high sensitivity

Inactive Publication Date: 2019-10-18
GUIZHOU UNIV
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, about half of the drugs are chiral drugs, and the two configurations of chiral enantiomers often have different physiological activities and pharmacological properties. The molecular structure of the drug must match the geometric structure of the receptor molecule to function. In terms of efficacy, usually only one of the chiral enantiomers is practical, and the other is ineffective or even toxic

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Electrochemical chiral sensor constructed by reduced graphene composite material
  • Electrochemical chiral sensor constructed by reduced graphene composite material
  • Electrochemical chiral sensor constructed by reduced graphene composite material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: a kind of reduced graphene composite material, is with attached figure 1 The chiral macrocyclic compound shown is obtained after functionalized reduction of graphene. The functionalization method is as follows: dissolve the reduced graphene in dimethyl sulfoxide, ultrasonicate for 2 hours at room temperature to obtain a suspension, and pour it into the suspension In the turbid liquid, add the macrocyclic compound with the mass ratio of reduced graphene: macrocyclic compound=1:2, control the mass concentration of the reduced graphene in the system to be 0.25mg / mL, then stir at room temperature for 40h, and obtain the function of the macrocyclic compound. reduced graphene composites.

[0029] The reduced graphene is prepared by the following method: at room temperature, graphene oxide is placed in secondary water for ultrasonication for 2 hours to disperse it into graphene oxide sheets; then add ascorbic acid in a mass ratio of 1:12, and stir at room tempera...

Embodiment 2

[0035] Embodiment 2: a kind of reduced graphene composite material is with attached figure 1 The chiral macrocyclic compound shown is obtained after functionalized reduction of graphene. The functionalization method is as follows: dissolve the reduced graphene in dimethyl sulfoxide, ultrasonicate for 2 hours at room temperature to obtain a suspension, and pour it into the suspension In the turbid liquid, add the macrocyclic compound with the mass ratio of reduced graphene: macrocyclic compound=1:2.5, control the mass concentration of the reduced graphene in the system to be 0.3mg / mL, then stir at room temperature for 60h, and obtain the function of the macrocyclic compound. reduced graphene composites.

[0036] The reduced graphene is prepared by the following method: at room temperature, graphene oxide is placed in secondary water and ultrasonically charged for 2 hours to disperse it into graphene oxide sheets; then add ascorbic acid in a mass ratio of 1:15, and stir at room ...

Embodiment 3

[0042] Embodiment 3: a kind of reduced graphene composite material, is with attached figure 1 The chiral macrocyclic compound shown is obtained after functionalized reduction of graphene. The functionalization method is as follows: dissolve the reduced graphene in dimethyl sulfoxide, ultrasonicate at room temperature for 1 hour to obtain a suspension, and pour the suspension into In the turbid liquid, the mass ratio of reduced graphene:macrocyclic compound=1:1.5 is added to the macrocyclic compound, and the mass concentration of the reduced graphene in the control system is 0.2mg / mL, and then stirred at room temperature for 20h to obtain the function of the macrocyclic compound. reduced graphene composites.

[0043] The reduced graphene is prepared by the following method: at room temperature, graphene oxide is placed in secondary water for 1 h to be dispersed into graphene oxide sheets; then ascorbic acid is added at a mass ratio of 1:10, and stirred at room temperature for 2...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an electrochemical chiral sensor constructed by a reduced graphene composite material. The reduced graphene composite material is obtained by functionally reducing graphene bya chiral macrocyclic compound; and the molecular formula of the chiral macrocyclic compound is C49H66N6O6. The electrochemical chiral sensor is constructed by modifying a substrate electrode with thereduced graphene composite material and is applied in identification and detection of tyrosine enantiomers. The reduced graphene composite material can be applied to modification of the substrate electrode of the electrochemical chiral sensor to realize identification and detection of the tyrosine enantiomer. The sensor has advantages of simple operation, fast response, low cost, high accuracy, high sensitivity, and low detection limit.

Description

technical field [0001] The invention relates to a graphene composite material and a sensor constructed thereof, in particular to a reduced graphene composite material and an electrochemical chiral sensor constructed thereof. Background technique [0002] Chirality refers to a phenomenon that molecules or ions cannot overlap with their mirror images. This is the asymmetry in the chemical structure caused by the three-dimensional arrangement of atoms that make up molecules or ions. A pair of mirror images is called "pair". Enantiomer". As an important geometric property of molecules or ions, chirality plays an important role in the fields of medicine, pharmacy and biochemistry. There are a large number of chiral molecules in nature and living organisms. Biomolecules that are important foundations of life activities, such as proteins, polysaccharides, and nucleic acids, are almost all chiral. In addition, about half of the drugs are chiral drugs, and the two configurations of...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/327G01N27/30
CPCG01N27/308G01N27/3275
Inventor 葛庆梅罗欢丛航晏燕
Owner GUIZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com