Food composition and oral preparation for improving visual fatigue, and preparation method of oral preparation
An oral preparation and visual fatigue technology, applied in the field of functional foods, can solve the problems of unsuitability for long-term use, high cost, and large side effects
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[0016] In the present invention, a preferred embodiment of the method for extracting cranberry extract comprises the following steps:
[0017] (1) Alcohol extraction: under acidic conditions, use ethanol aqueous solution to extract the cranberry raw material, and coarsely filter to obtain the extract;
[0018] (2) Ethyl acetate extraction: the extract is suction filtered to obtain the filtrate, then the filtrate is concentrated under reduced pressure until the relative density is 1-1.5 to obtain the liquid to be extracted, and then extracted with ethyl acetate;
[0019] (3) Drying: the extract is vacuum-dried until the moisture content is less than 5% by weight;
[0020] (4) Pulverization and sieving: pulverize the dry matter and pass through a 60-100 mesh sieve.
[0021] In the step (1) of the bilberry extract extraction method of the present invention, the solid-to-liquid ratio (weight ratio) of the bilberry raw material to the ethanol aqueous solution is 1: 8-15; the extra...
Embodiment 1
[0052] This example is used to illustrate the cranberry extract provided by the present invention and its preparation method.
[0053] (1) Alcohol extraction: extract the bilberry with a 75% ethanol aqueous solution with a mass concentration of 75%, the ratio of solid to liquid (weight ratio) is 1:10, adjust the pH to 3.0 with HCl, extract at 60°C for 1 hour, and coarsely filter to obtain the extract ;
[0054] (2) Ethyl acetate extraction: filter the extract through a plate-and-frame filter to obtain the filtrate, and then concentrate the filtrate under reduced pressure at a vacuum degree of -0.06MPa and a temperature of 65°C until the relative density is 1.2 (60°C). Obtain the liquid to be extracted, then extract with 2 times the volume of ethyl acetate, and extract twice;
[0055] (3) Drying: vacuum-dry the extract at a vacuum degree of -0.08MPa, below 60°C, until the moisture content is less than 5% by weight;
[0056] (4) Pulverization, sieving, and inspection: the dry ...
Embodiment 2
[0058] This example is used to illustrate the oral preparation provided by the present invention and its preparation method.
[0059] (1) premixing: take by weighing 100g lutein raw material, 70g of the cranberry extract that embodiment 1 makes pass respectively 40 mesh sieves, mix;
[0060] (2) Mixing and granulation: take by weighing 271g microcrystalline cellulose, mix uniformly with the above-mentioned premix, add ethanol that accounts for 15% by weight of the mixture and have a mass concentration of 50%, and stir to obtain wet granules; then wet granules The material is transferred to the boiling drier for drying. When the temperature reaches 45°C, keep it warm for 25 minutes and then cool it down to below 40°C. When the water content of the pellets is 4% by weight, discharge the pellets and pass through a 20-mesh sieve to obtain dry pellets;
[0061] (3) 4.5g of magnesium stearate was weighed, mixed uniformly with dry granules, compressed into tablets and packaged to ob...
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