Unlock instant, AI-driven research and patent intelligence for your innovation.

Method for preparing 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (5-HMF)

A technology of hydroxymethyl furfural and furandicarboxylic acid, applied in the field of chemical preparation, can solve the problems of high reaction conditions and poor product selectivity, and achieve the effects of simple process, high selectivity and yield, and increased solubility

Active Publication Date: 2019-11-12
UNIV OF SCI & TECH OF CHINA
View PDF5 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Base metal catalysts have cost advantages, but higher reaction conditions and poor product selectivity

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (5-HMF)
  • Method for preparing 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (5-HMF)
  • Method for preparing 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (5-HMF)

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] In a 10 mL Shrek tube, charge 126 mg 5-hydroxymethylfurfural (5-HMF), 11 mg Catalyst 1, and 24 mg NaNO 2 , then add 60mg H 3 PO 4 , 0.2mL of water and 2mL of tert-butanol, and heated to 55°C in a water bath for 48h in an oxygen atmosphere at normal pressure with magnetic stirring (stirring rate: 800r / min). After the reaction was completed, samples were sent to high-performance liquid chromatography (HPLC) under agitation for detection, wherein the detection conditions were as follows: Hitachi L2000 HPLC System, Alltech C18 column, mobile phase CH 3 OH:H 2 O=20:80; flow rate: 1.0 mL / min, column temperature: 30° C., detector: DAD, detection wavelength: 264 nm. As detected by HPLC, the yield of the product 2,5-furandicarboxylic acid (FDCA) was 92.17%, the selectivity was 95%, and its purity was 99%.

Embodiment 2

[0043] Concrete reaction process and detection method are identical with embodiment 1, only change tert-butanol into 3-methyl-pentan-3-alcohol, as a result gained main product is 2,5-furandicarboxylic acid (FDCA), and receive The yield was 85.76%, the selectivity was 96%, and its purity was 99.3%.

Embodiment 3

[0045] Concrete reaction process and detection method are identical with embodiment 1, just change tert-butanol into tert-amyl alcohol, as a result gained main product is 2,5-furandicarboxylic acid (FDCA), and yield is 80.33%, selectivity is 98%, and its purity is 98.6%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for preparing 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (5-HMF). The method comprises the steps: at the temperature of 30-100 DEG C, in a mixed solvent of a tertiary alcohol compound and water, the raw material 5-HMF reacts in the presence of a TEMPO catalyst, inorganic acid or solid acid cocatalyst, a nitrite assistant and an oxidant to be converted into the 2,5-FDCA. Through the method, the raw material 5-HMF can be converted into the target product, namely the 2,5-FDCA at high selectivity and the high yield under mild conditions, the process route is simple, and the great industrial application prospect is achieved.

Description

technical field [0001] The invention relates to a preparation method of chemicals, in particular to a method for preparing 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (5-HMF). Background technique [0002] Declining oil resources and global warming require people to look for a green and sustainable energy source to reduce dependence on fossil fuels. 2,5-furandicarboxylic acid (FDCA), as a new polymer structure monomer, has stable performance. It can be used to prepare polyester, polyamide and polyurethane, etc. Polyethylene furandicarboxylate (PEF) prepared by FDCA is considered to be an important polyester material to replace polyethylene terephthalate (PET). It has the advantages of biodegradability and environmental protection. FDCA also plays an important role in pharmacology. Studies have shown that diethyl furandicarboxylate has a strong anesthetic effect similar to cocaine. Dicalcium furandicarboxylate inhibits the growth of Bacillus megaterium. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07D307/68
CPCC07D307/68
Inventor 傅尧解光霞李兴龙孔庆山沈鸿波
Owner UNIV OF SCI & TECH OF CHINA