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Milk substrate liposome eye gel for resisting wrinkles and removing fat granules and dark eye circles and preparation method of milk substrate liposome eye gel

A technology for dark circles and fat granules, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc. Improves skin condition, absorbs well, and removes fat particles

Active Publication Date: 2019-12-03
TIANJIN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The active ingredients in existing eye cream products only stay in the stratum corneum of the skin, and it is difficult to enter the basal layer cells to play the fundamental role of anti-oxidation and anti-wrinkle, removing dark circles, removing fat particles, and improving skin condition. Most of them can only moisturize the stratum corneum. skin effect
Active ingredients are mostly wasted due to the lack of a good skin deep delivery system and cannot achieve the desired effect

Method used

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  • Milk substrate liposome eye gel for resisting wrinkles and removing fat granules and dark eye circles and preparation method of milk substrate liposome eye gel
  • Milk substrate liposome eye gel for resisting wrinkles and removing fat granules and dark eye circles and preparation method of milk substrate liposome eye gel
  • Milk substrate liposome eye gel for resisting wrinkles and removing fat granules and dark eye circles and preparation method of milk substrate liposome eye gel

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0077] A kind of preparation method of the milk matrix liposome eye cream of anti-wrinkle removing fat granules and dark circles as described above, the steps are as follows:

[0078] S1, first, stir and mix the active polypeptide, ginsenoside and yeast essence with the milk matrix liposome, incubate at 32-36°C for 5-10 minutes, and keep stirring;

[0079] Then, the water is spin-dried by the film dispersion method to form a honeycomb film;

[0080]Then, add tea polyphenols, dissolve the honeycomb membrane, homogenize for 2-8 minutes, and pressure 1000-5000psi, to prepare milk matrix liposomes carrying active ingredients;

[0081] Finally, heat the milk-based liposomes loaded with active ingredients to 50-80°C;

[0082] S2, mixing sweet almond oil, Tween 80, Span 80, α-bisabolol and vitamin E in the oil phase in proportion at 50-80°C to obtain the oil phase;

[0083] S3, adding xanthan gum and sodium alginate into water in proportion, stirring to form a uniformly mixed gel m...

Embodiment 1

[0095] A milk base liposome eye cream for anti-wrinkle and anti-fat particles and dark circles is obtained by the following raw materials and methods in weight percentage:

[0096] Raw materials: Soy milk liposome 50%, active peptide 0.3%, ginsenoside 0.2%, yeast extract 0.01%, sweet almond oil 6%, Tween 800.5%, Span 800.75%, xanthan gum 0.5%, sodium alginate 0.25 %, 0.5% of α-bisabolol, 1% of tea polyphenols, 0.5% of vitamin E, 0.1% of hyaluronic acid, 4% of trehalose, 0.6% of ε-polylysine, and the balance of distilled water.

[0097] The preparation method is as follows:

[0098] S1. Stir and mix the active polypeptide, ginsenoside and yeast essence with soy milk liposomes evenly, incubate at 33°C for 8 minutes, and keep stirring; then, spin dry the water by thin film dispersion method to form a honeycomb film; then, add tea polyphenols Aqueous solution, dissolving honeycomb membrane, homogeneous for 6 minutes, pressure is 2500psi, makes the soybean milk liposome of encapsu...

Embodiment 2

[0103] A milk base liposome eye cream for anti-wrinkle and anti-fat particles and dark circles is obtained by the following raw materials and methods in weight percentage:

[0104] Raw materials: 50% milk liposome, 0.3% active peptide, 0.2% ginsenoside, 0.01% yeast extract, 6% sweet almond oil, 800.5% Tween, 800.75% span, 0.5% xanthan gum, 0.25 sodium alginate %, 0.5% of α-bisabolol, 1% of tea polyphenols, 0.5% of vitamin E, 0.1% of hyaluronic acid, 4% of trehalose, 0.6% of ε-polylysine, and the balance of distilled water.

[0105] The preparation method is as follows:

[0106] S1. Stir and mix the active polypeptide, ginsenoside and yeast essence with milk liposomes evenly, incubate at 33°C for 8 minutes, and keep stirring; then, spin dry the water by film dispersion method to form a honeycomb film; then, add tea polyphenols Aqueous solution, dissolving honeycomb membrane, homogeneous for 6 minutes, pressure is 2500psi, makes the milk liposome of encapsulating active ingredi...

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Abstract

The invention relates to milk substrate liposome eye gel for resisting wrinkles and removing fat granules and dark eye circles. The milk substrate liposome eye gel consists of the following componentsin parts by weight of 10-60 parts of milk substrate liposome, 0.1-1 part of bioactive peptide, 0.1-1 part of ginsenoside, 0.002-0.01 part of yeast essence, 3-10 parts of sweet almond oil, 0.1-2 partsof tween 80, 0.1-2 parts of span 80, 0.2-2 parts of xanthan gum, 0.1-1 part of sodium alginate, 0.2-1 part of alpha-bisabolol, 1-3 parts of tea polyphenols, 0.1-5 parts of vitamin E, 0.01-1 part of hyaluronic acid, 1-5 parts of trehalose, 0.01-3 parts of epsilon-polylysine and the balance distilled water, wherein all of the components are 100 parts. The eye gel has the effects of lightening darkeye circles, resisting wrinkles, and removing fat granules. In addition, the bisabolol and the polylysine are united for use for the first time to replace chemical preservatives, so that stimulation effect on sensitive skin and muscle is eliminated.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, in particular to a milk-based liposome eye cream for anti-wrinkle and anti-fat particles and dark circles and a preparation method thereof. Background technique [0002] Active polypeptide is a water-soluble protein extracted from plants. It can effectively reduce skin melanin, dilute and prevent the formation of melanin, significantly increase the skin's ability to keep warm and lock water, reduce aging cells on the skin surface, and soften skin cuticles. Cells, promote cell metabolism, accelerate the microcirculation of capillaries, strengthen the collagen-white connection between cells, and make the skin white, soft, crystal clear and full of elasticity. It is a specific removal of oxygen free radicals recognized at home and abroad agent. It has anti-aging effects, can be directly absorbed by the human body quickly, and participates in the regulation of metabolic processes. It is an essenti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/98A61K8/9728A61K8/92A61K8/88A61K8/73A61K8/67A61K8/14A61K8/34A61K8/64A61Q19/00A61Q19/08
CPCA61K8/9728A61K8/922A61K8/88A61K8/735A61K8/733A61K8/678A61K8/64A61K8/986A61K8/342A61K8/14A61Q19/00A61Q19/08A61Q19/005A61K2800/84
Inventor 李明媛郁彭郭娜滕玉鸥李双双杜春阳王栋
Owner TIANJIN UNIV OF SCI & TECH
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