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Application of nitraria tangutorum extract and skin externally applied preparation containing nitraria tangutorum extract

A technology of external skin preparations and extracts, which is applied in the field of skin external preparations and can solve problems such as lack of active substances

Active Publication Date: 2020-01-31
JALA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] The technical problem solved by the present invention is aimed at the lack of active substances that can be used to improve the skin's anti-oxidation and anti-aging capabilities in the prior art, and provides an application of Nitraria japonica extract and an external preparation for skin containing it

Method used

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  • Application of nitraria tangutorum extract and skin externally applied preparation containing nitraria tangutorum extract
  • Application of nitraria tangutorum extract and skin externally applied preparation containing nitraria tangutorum extract
  • Application of nitraria tangutorum extract and skin externally applied preparation containing nitraria tangutorum extract

Examples

Experimental program
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Effect test

Embodiment 1

[0078] The preparation of embodiment 1 Nitraria japonica seed extract

[0079] Crush the sun-dried Nitraria seeds, pass through a 40-mesh sieve, and put them into a supercritical extractor. The feeding amount is 300g at a time, the extraction pressure is 35MPa, the extraction temperature is 45°C, CO 2 The flow rate is 25kg / h, and the condition of supercritical CO 2 Extraction, the extraction time was 2.5 hours, and the Nitraria seed oil was taken from the separation kettle; a total of 5 times of feeding, 1.5Kg of raw materials were extracted, and 150g of Nitraria seed oil was obtained. Weigh 10 g of Nitraria japonica seed oil, pass through the macroporous adsorption resin AB-8, and successively elute with 1 times of column volume of water and 5 times of column volume of 30% ethanol, and discard the eluent. Then, it was eluted with 70% ethanol of 5 times of column volume, and the eluate was collected, concentrated and evaporated to dryness to obtain 0.9 g of dry powder of Nitr...

Embodiment 2

[0081] According to the following components and dosage, the lotion is prepared, and the percentage refers to the weight percentage of each component in the lotion:

[0082] Glycerin 5%, Butylene Glycol 3%, Betaine 1%, Panthenol 0.5%, Dipotassium Glycyrrhizinate 0.1%, Allantoin 2.0%, Polyethylene Glycol-32 0.5%, Hydroxyethyl Cellulose 0.15-0.2 %, IS-45 0.4%, xanthan gum 0.15%, spices 0.03% and Nitraria seed extract 0.005%; the rest is added to 100% with deionized water.

[0083] The external preparation for skin in this example was prepared according to the conventional preparation method of lotion in this field.

Embodiment 3

[0085] According to the following components and dosage, the essence is prepared, and the percentage refers to the weight percentage of each component in the essence:

[0086] Glycerin 5%, Butylene Glycol 3%, Panthenol 1%, Dipotassium Glycyrrhizinate 0.1%, Allantoin 0.1%, Niacinamide 4%, Hydroxyethylcellulose 0.05%, Methylparaben 0.15%, Phenoxy Ethanol 0.3%, xanthan gum 0.2%, acrylic resin Pemulen TR-2 0.3%, spice 0.05% and Nitraria seed extract 0.1%; the rest was supplemented to 100% with deionized water.

[0087] The external preparation for skin in this example was prepared according to the conventional preparation method of essence in this field.

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Abstract

The invention provides application of a nitraria tangutorum extract and a skin externally applied preparation containing the nitraria tangutorum extract. The application specifically means one or moreapplications of the nitraria tangutorum extract in preparation of antioxidants, melanin biosynthesis inhibitors, elastic fiber hydrolysis inhibitors and skin-aging resistant protein expression up-regulators. The nitraria tangutorum extract, especially a nitraria tangutorum seed extract, has the effects of scavenging the activity of free radicals, inhibiting the activity of tyrosinase, inhibitingthe activity of elastase and improving expression of anti-aging protein in human fibroblasts, can regulate synthesis of collagen in dermis and has the effect of delaying senescence.

Description

technical field [0001] The present invention relates to the application of Nitraria japonicus extract and the skin external preparation containing it. Background technique [0002] With the continuous development and maturity of the skin care product market, more and more brands are emerging. Consumers demand for the efficacy of skin care products and hope to see effective skin care effects. Therefore, research on the efficacy mechanism of active substances in skin care products is required. The level needs to be improved. As the interpretation of the efficacy mechanism becomes more and more in-depth, it cannot be limited to simply describing the appearance, but needs to integrate cutting-edge biotechnology. With the continuous development of cell biology technology, the discovery of skin biology It has also continued to deepen, and more targets and regulatory mechanisms related to the functional structure of the skin have been discovered. [0003] The skin is the largest o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/9789A61Q19/00A61Q19/02A61Q19/08A61K2800/782Y02P20/54
Inventor 李慧摩根多斯桑托斯章漳蒋丹丹秦优
Owner JALA GROUP CORPORATION
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