Gelata for treating cervicitis and cervical erosion

Abstract

The invention discloses gelata for treating cervicitis and cervical erosion. The gelata is prepared from the following raw materials in parts by weight of 0.1-0.5 part of an antioxidant, 0.1-0.5 partof ethylenediamine tetraacetic acid disodium salt, 80-90 parts of deionized water, 2-5 parts of carbomer, 2-5 parts of Yipiwutai, 40-50 parts of ethanol,13-15 parts of a hydrating agent, 6-8 parts ofa surfactant, 2-5 parts of laurocapram and 3-6 parts of a pH-regulating agent. In the process of preparing the gelata, the surfactant is prepared, and the surfactant molecule contains hydrophilic groups and hydrophobic groups, so that when the surfactant molecule is in contact with the surfaces of cells, the surfactant molecule and a cell membrane mutually dissolve, phospholipid molecules on the cell membrane cannot be arrayed to a tidy and order cell membrane, and the permeability of the cell membrane is further improved. The surfactant molecules contain liposoluble groups, so that the surfactant molecules can well react with the cell membrane.

Description

technical field [0001] The invention belongs to the field of gels, in particular to a gel for treating cervical inflammation and erosion. Background technique [0002] Gels refer to thick liquid or semi-solid preparations made of a drug and gel-forming excipients in the form of solutions, suspensions, or emulsions. Usually, gels are limited to local use on the skin and body cavities. Emulsion-type gels Also known as latex agent, the gel agent made of polymer matrix can also be called mucilage agent, the gel agent formed by the small particles of small molecular inorganic drugs existing in the liquid in a network structure, which belongs to two-phase dispersion System, also known as suspension gel, suspension gel can be thixotropic, it is semi-solid at rest and becomes liquid when stirred or shaken, traditional gel is applied to the skin surface, due to the gel The medicinal ingredients in the gel are absorbed for a long time, so that the medicinal ingredients in the gel are...

AI Technical Summary

Problems solved by technology

[0002] Gels refer to thick liquid or semi-solid preparations made of a drug and gel-forming excipients in the form of solutions, suspensions, or emulsions. Usually, gels are limited to local use on the skin and body cavities. Emulsion-type gels Also known as latex agent, the gel agent made of polymer matrix can also be called mucilage agent, the gel agent formed by the small particles of small molecular inorganic drugs existing in the liquid in a network structure, which belongs to two-phase dispersion System, also known as suspension gel, suspension gel can be thixotropic, it is semi-solid at rest and becomes liquid when stirred or shaken, traditional gel is applied to the skin surface, due to the gel The medicinal ingredients in the gel are absorbed for a long time, so that the medicinal ingredients in the gel are not fully absorbed, and the gel will solidify, which affects the absorption of the medicinal ingredients;

[0003] Chinese invention patent CN101049286B discloses a gel preparation containing ciclopirox olamine, which is made of the following components: ciclopirox olamine 1-50g, carbomer 1-50g, ethanol 10-500g, propylene glycol 20 -500g, triethanolamine 0-50g, edetate disodium 0.05-2.0g, polysorbate 8010-100g, add water to 1000g, the gel has lubricity, easy to spread, and long-lasting drug effect, but The gel preparation film is applied on the skin surface, and it takes a long time to be absorbed by the cells. At the same time, the cell absorption rate is low, and it takes a long time to make the drug effective, which is not conducive to the treatment of diseases.

Images