High-molecular soluble microneedle and production method thereof

A production method and soluble technology, applied in the field of polymer soluble microneedles and its production, can solve the problem of depth problem, insufficient effect, increase of beauty cycle and cost, and unsimplified operation process, so as to achieve simple and time-saving production method, Good wrinkle removal and strong operability

Pending Publication Date: 2020-04-24
广东雅姿精化有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Nowadays, beauty products and technologies on the market are mixed. For women who love beauty, on the one hand, they are afraid of the high risks of medical beauty. Reliable and high-efficiency methods occupy an increasingly important position in the beauty field; however, traditional microneedles are insufficient in injection quality, penetration and penetration density, and are very effective in solving skin water-locking, fine lines

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] This embodiment includes a polymer soluble microneedle and its production method.

[0035] A polymer soluble microneedle, which is composed of a needle body and a substrate; the needle body is composed of the following substances in parts by weight: 10 parts of hyaluronic acid, 0.5 parts of polyglutamic acid, 3 parts of tremella polysaccharide, and 2 parts of vitamin C ethyl ether 0.003 parts of oligopeptide-1, 0.002 parts of oligopeptide-3, 0.001 parts of oligopeptide-5, 5 parts of cannabidiol, 1.5 parts of arbutin, 0.1 parts of rhodiola extract, 0.3 parts of vitamin E, ginseng extract 5 parts, 0.5 parts of Sophora flavescens extract, 2 parts of Panax notoginseng extract, 0.5 parts of rose essential oil, 7 parts of trehalose, 30 parts of polyvinyl alcohol, 0.2 parts of polyvinyl pyrrolidone, 5 parts of soluble starch, 7 parts of glycerin, 23 parts of water parts; the substrate is composed of the following parts by weight: 20 parts of polyvinyl alcohol, 80 parts of wate...

Embodiment 2

[0047] This embodiment includes a polymer soluble microneedle and its production method.

[0048] A polymer soluble microneedle, which is composed of a needle body and a substrate; the needle body is composed of the following materials in parts by weight: 5 parts of hyaluronic acid, 5 parts of polyglutamic acid, 0.2 parts of tremella polysaccharide, and 0.5 parts of vitamin C ethyl ether 0.002 parts of oligopeptide-1, 0.003 parts of oligopeptide-3, 0.002 parts of oligopeptide-5, 0.5 parts of cannabidiol, 2.5 parts of arbutin, 5 parts of Rhodiola rosea extract, 0.7 parts of vitamin E, ginseng extract 3 parts, 0.1 part of Sophora flavescens extract, 0.1 part of Panax notoginseng extract, 0.4 part of rose essential oil, 3 parts of trehalose, 10 parts of polyvinyl alcohol, 2 parts of polyvinyl pyrrolidone, 3 parts of soluble starch, 5 parts of glycerin, 70 parts of water parts; the substrate is composed of the following parts by weight: 10 parts of polyvinyl alcohol, 90 parts of w...

Embodiment 3

[0051] This embodiment includes a polymer soluble microneedle and its production method.

[0052] A polymer soluble microneedle, consisting of a needle body and a substrate; the needle body is composed of the following substances in parts by weight: 15 parts of hyaluronic acid, 3 parts of polyglutamic acid, 3.5 parts of tremella polysaccharide, 5 parts of vitamin C ethyl ether 0.004 parts of oligopeptide-1, 0.004 parts of oligopeptide-3, 0.003 parts of oligopeptide-5, 1.5 parts of cannabidiol, 1 part of arbutin, 0.5 parts of rhodiola extract, 1 part of vitamin E, ginseng extract 0.1 part, 1 part of Sophora flavescens extract, 0.5 part of Panax notoginseng extract, 0.3 part of rose essential oil, 1 part of trehalose, 15 parts of polyvinyl alcohol, 0.6 part of polyvinyl pyrrolidone, 1 part of soluble starch, 10 parts of glycerin, 45 parts of water parts; the substrate is composed of the following parts by weight: 15 parts of polyvinyl alcohol, 85 parts of water.

[0053] The pr...

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Abstract

The invention discloses a high-molecular soluble microneedle and a production method thereof. The high-molecular soluble microneedle is composed of a needle body and a substrate; the needle body is composed of hyaluronic acid, polyglutamic acid, tremella polysaccharide, vitamin C ethyl ether, oligopeptide-1, oligopeptide-3, oligopeptide-5, cannabidiol, arbutin, rhodiola rosea extract, vitamin E, ginseng extract, radix sophorae flavescentis extract, pseudo-ginseng extract, rose essential oil, trehalose, polyvinyl alcohol, polyvinylpyrrolidone, soluble starch, glycerol and water; and the substrate is composed of polyvinyl alcohol and water. The production method of the microneedle comprises the following steps: weighing the components in parts by weight, respectively carrying out vacuum stirring dissolution on the components of the needle body and the substrate, carrying out high-pressure molding on the needle body part through a mold and a high-pressure device, coating the mold with a vacuum stirring dissolution solution of the substrate, and carrying out freeze drying to obtain the microneedle. The product is good in penetrability, safe, reliable and convenient to use; the production method is simple, time-saving and high in feasibility.

Description

technical field [0001] The invention relates to a microneedle and a production method thereof, in particular to a polymer soluble microneedle and a production method thereof. Background technique [0002] Nowadays, beauty products and technologies on the market are mixed. For women who love beauty, on the one hand, they are afraid of the high risks of medical beauty. Reliable and high-efficiency methods occupy an increasingly important position in the beauty field; however, traditional microneedles are insufficient in injection quality, penetration and penetration density, and are very effective in solving skin water-locking, fine lines, and dry lines. The effect of equal-depth problems is not significant enough, which increases the beauty cycle and cost; micro-needle beauty is a medical beauty project, which requires strict operation by beauty technicians in regular beauty institutions. The needle operation process has not been simplified and is still very cumbersome. Ther...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/92A61K8/88A61K8/81A61K8/73A61K8/67A61K8/64A61K8/60A61K8/02A61Q19/00A61Q19/02A61Q19/08A61M37/00
CPCA61K8/9789A61K8/922A61K8/88A61K8/735A61K8/73A61K8/676A61K8/64A61K8/732A61K8/678A61K8/602A61K8/8129A61K8/0208A61Q19/00A61Q19/02A61Q19/08A61M37/0015A61K2800/91A61M2037/0053A61M2037/0046
Inventor 杰·汉密尔顿韩斌陈文廷谭卉刘伟豪
Owner 广东雅姿精化有限公司
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