Liquid dressing and preparation method thereof

A technology of liquid dressings and raw materials, which is applied in the fields of medical formula, medical science, and drug delivery. simple effect

Active Publication Date: 2020-05-01
成都博创必成生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the adhesive tape used has poor air permeability, and the water vapor and sweat normally secreted by the human body cannot penetrate this layer of adhesive tape, which will soak the damaged skin, making the wound and the skin around the wound white and soft, leading to secondary infection of bacteria aggravate the wound
In addition, during the wound healing process, granulation tissue will slowly grow towards the center of the adhesive plaster, causing the adhesive plaster to closely adhere to the new tissue, which is difficult to remove, and causes tearing of the new tissue, and may even make the wound aggravate, increase the patient's suffering
In addition, sticking strip-shaped adhesive plasters on the affected area will affect the appearance, and it is not suitable for irregular wounds.

Method used

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  • Liquid dressing and preparation method thereof
  • Liquid dressing and preparation method thereof
  • Liquid dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0026] The preparation method of the above-mentioned liquid dressing comprises: taking raw materials, mixing and stirring, and obtaining.

[0027] The above liquid dressing formulations are in the form of a spray.

Embodiment 11～14

[0028] The specific implementation method of embodiment 11~14 preparation method is:

[0029] A preparation method of liquid dressing for wound surface comprises:

[0030] (1) Get the raw materials, in parts by weight, the raw materials are shown in Table 1;

[0031] (2) The polyvinyl acid resin IV is mixed with the absolute ethanol, and stirred to obtain a solution 1;

[0032] (3) The ethyl acetate is mixed with the solution 1 and stirred to obtain a solution 2;

[0033] (4) The hydrogenated castor oil is mixed with the solution 2, stirred, and obtained.

[0034] Table 1

[0035]

[0036] 1. Viscosity test

[0037] Under the condition of 15-20°C, take an appropriate amount of the liquid dressings of Examples 1-15 respectively, turn on the digital viscometer, select the SP21 rotor to rotate for 2 minutes, then take a reading, stop for 2 minutes, repeat the experiment 2 times, and take the results of the 3 experiments. On average, the results are shown in Table 2, and t...

Embodiment 1～15

[0041] Sample: liquid dressings of Examples 1-15

[0042] Take 2 clean Petri dishes and dry them at 105±2°C for 30 minutes. Take it out and put it in a desiccator, after cooling to room temperature, weigh it. Then put it into the oven and bake for 30 minutes, take it out and put it in a desiccator to cool to room temperature, and then weigh it until the weight difference between the two weighings is not more than 0.01g (all weighing is accurate to 0.001g). Weigh 1-2g of the sample into the two weighed Petri dishes respectively, with an accuracy of 0.001g, so that the sample evenly spreads on the bottom of the container, and then put it in a constant temperature oven adjusted to 105°C for baking After 30 minutes, take it out and put it in a desiccator to cool to room temperature, weigh it, then put it in an oven and bake it for 30 minutes, take it out and put it in a desiccator, cool it to room temperature, weigh it, and weigh it twice before and after. The weight difference ...

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PUM

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Abstract

The invention discloses a liquid dressing and a preparation method thereof. The liquid dressing is prepared from raw materials, by weight, 55-70 parts of absolute ethyl alcohol, 7-22 parts of polyacrylic resin IV, 5-25 parts of ethyl acetate and 0.1-3 parts of lubricant; the liquid dressing is simple in component, free of irritation to skin, safe to use, short in film-forming time, good in toughness and good in film-forming property, can be directly sprayed on the surface of a superficial wound, has the effects of stopping bleeding, protecting the wound, adhering the epidermis, preventing water and inhibiting bacteria, and can be used for nursing irregular wounds.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a liquid dressing and a preparation method thereof. Background technique [0002] Skin is the body's first barrier against external invasion, and it is also the largest tissue in the body. The damage of skin tissue will not only cause the destruction of subcutaneous tissue, but also affect the internal balance of the body. In the field of daily life and medical care, protecting intact skin or damaged skin from further damage (such as sharp cuts, burns, abrasions, etc.) has attracted more and more attention and attention. In the process of wound healing, The use of wound dressings is very important for the healing of skin injuries and protects the wound from external aggressions, including physical contact injuries and secondary infection by microorganisms such as bacteria. [0003] Traditional wound dressings currently on the market still play a powerful role, although ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0014A61L26/0057A61L26/0061A61L2400/04C08L33/02
Inventor 万方杨华蓉刘虹均张劲松邓少东杨青
Owner 成都博创必成生物技术有限公司
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