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Breast imaging device and method based on adjustable LED and dynamic SiPM

A breast imaging and LED light source technology, applied in the field of medical image analysis, can solve problems such as high price, difficulty in early inspection, inspection range or complexity of equipment, etc., and achieve low-cost effects

Inactive Publication Date: 2020-05-19
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the breast cancer examination equipment commonly used in early clinical examination is the large mammography imaging machine in the hospital. Because the examination will cause certain radiation damage and the early examination is difficult, it is not conducive to health.
Ultrasound can't resolve early cancers well
However, MRI and CT are more expensive in price and are not suitable for examination of local areas of the body.
The above reasons make these technologies insufficient in terms of price, radiation, inspection scope or equipment complexity

Method used

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  • Breast imaging device and method based on adjustable LED and dynamic SiPM
  • Breast imaging device and method based on adjustable LED and dynamic SiPM
  • Breast imaging device and method based on adjustable LED and dynamic SiPM

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1: as Figure 5 Shown are the near-infrared absorption spectra of oxygenated hemoglobin, reduced hemoglobin and water, and the near-infrared light at 700-1300nm is called the "tissue light window". figure 1 It can be seen that the absorption spectrum of water is mainly in the band around 1000nm. Oxygenated hemoglobin and reduced hemoglobin have different absorption characteristics for red light and near-infrared light. The isoabsorptive point is at 805nm, and 760nm and 850nm are points at the same distance from the isoabsorptive point around 805 nm. Combined with oxygenated hemoglobin And the absorption spectrum of reduced hemoglobin and water, so these two wavelengths are selected for measurement.

Embodiment 2

[0050] Embodiment 2: as figure 2 As shown, in this embodiment, the adjustable LED light source module is used to irradiate the detected part to obtain the corresponding hemoglobin concentration distribution map, so as to diagnose the tumor. The adjustable LED and dynamic SiPM imaging device in this embodiment mainly include: LED infrared light source module 100, photoelectric conversion detector module 200, consistent time processing circuit module 300, image reconstruction and visualization module 400 and global clock module 500; LED infrared light source device module 100 includes LED light source module 110, breast negative pressure fixation Module 120, control circuit module 130; Photoelectric conversion detector module 110 includes left side CCD module 220, SiPM module 230, right side CCD module 240 and band-pass filter module 210; Meets time processing circuit module 300 and includes amplifying circuit module 310 , sampling operation module 320, analog-to-digital conver...

Embodiment 3

[0054] Embodiment 3: Perform power spectrum and cross-correlation analysis on the collected optical signals.

[0055] Power spectrum analysis, the random signal X(n) N point observation value X N (n) As a signal with limited energy, take its Fourier transform and get X N (e jw ), then take the square of its magnitude and divide it by N as the real power spectrum P(e of X(n) jw ) estimates. In the specific application, FFT is used to calculate the sampling of the signal spectrum, and the corresponding power spectrum is estimated as:

[0056]

[0057] What the Fourier transform reveals is the inner connection between the time function and the spectrum function, reflecting all the spectrum components of the signal in the entire time range. When using Fourier transform method to extract the signal spectrum, it is necessary to use all the time domain information of the signal. Local changes in the signal affect the entire frequency spectrum of the signal. The collected out...

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Abstract

The invention relates to a breast imaging device and method based on adjustable LED and dynamic SiPM. The device includes an LED infrared light source module, a photoelectric conversion detector module, a coincidence time processing circuit module, and an image reconstruction and display module. The imaging method comprises the following steps: S1, adsorbing and fixing a breast part by using a negative pressure device; S2, performing transmission on the breast part by using an infrared LED light source, and acquiring transmitted light signals by using the photoelectric conversion detector module; S3, processing the signals by using the coincidence time processing circuit module; and S4, performing blood oxygen protein concentration distribution imaging and visualization by using the imagereconstruction and display module. The breast imaging method based on the adjustable LED and the dynamic SiPM can use the LED light source to perform non-radiation transillumination on the breast part, the device costs are lower, the photoelectric conversion detector module can accurately acquire more information about the breast, the breast part is adsorbed and fixed by the negative pressure module, and the method has the characteristics of deformation resistance and respiratory artifact resistance.

Description

technical field [0001] The invention relates to the technical field of medical image analysis, in particular to a breast imaging device and method based on an adjustable LED and a dynamic SiPM. Background technique [0002] The female mammary gland is composed of skin, fibrous tissue, mammary glands and fat. Breast cancer is a malignant tumor that occurs in the mammary gland epithelial tissue. 99% of breast cancers occur in women and only 1% in men. Breast cancer is a gene mutation in breast glandular epithelial cells under the action of various carcinogenic factors, resulting in uncontrolled cell proliferation. As the biological behavior of cancer cells has changed, it presents disordered and unrestricted malignant proliferation. Its histological manifestation is that a large number of immature cancer cells proliferate indefinitely and crowd into groups in a disorderly manner, extruding and eroding to destroy the surrounding normal tissues and destroy the normal tissue st...

Claims

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Application Information

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IPC IPC(8): A61B5/00
CPCA61B5/0033A61B5/0075A61B5/489
Inventor 邓贞宙陈卓
Owner NANCHANG UNIV
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