The invention discloses a silver-plated polyester filament yarn wrapped in a cotton yarn and a manufacturing method thereof as well as a yarn core wrapping device. The silver-plated polyester filament yarn wrapped in a cotton yarn is characterized by comprising a silver-plated polyester filament yarn and a cotton yarn, and the cotton yarn is spirally wrapped outside the silver-plated polyester filament. After the technical measure above is adopted, the silver-plated polyester filament yarn wrapped in a cotton yarn has the advantages that: 1. the silver-plated polyester filament yarn is wrapped in the cotton yarn, therefore, the hardiness, flex resistance and resistant force of the manufactured silver-plated polyester filament yarn are enhanced; 2. the silver-plated polyester filament yarn is wrapped in the cotton yarn, so that the manufactured silver-plated polyester filament yarn has small possibility of dropping and being oxygenized, and even if dropping, the silver-plated polyester filament yarn also can drop in the wrapping of two cotton yarns, therefore, the radiation protection performance of the silver-plated polyester filament yarn is not affected; and 3. the silver-plated polyester filament yarn is wrapped in the cotton yarn, so that the manufactured silver-plated polyester filament yarn can be dyed, and can be washed and reused repeatedly, therefore, the radiation hazards can be shielded permanently, and the shielding effect of the silver-plated polyester filament yarn is better than those of other fabrics. In the invention, the operations of core wrapping and twisting can be completed in one step.