Traditional Chinese medicine liniment for treating dog and cat skin diseases and preparation method thereof

A smear and skin disease technology, which is applied in the field of traditional Chinese medicine smear for treating skin diseases of dogs and cats and its preparation, can solve the problems of exacerbation of disease, side effects, treatment of roughness, etc., and achieve the effect of alleviating itching symptoms

Inactive Publication Date: 2020-05-19
BEIJING UNIV OF AGRI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, skin diseases must be accurately diagnosed before treatment, and the current clinical treatment of skin diseases is generally rough and treated with empirical medication without diagnosis, resulting in serious drug abuse, resulting in delays or even worsening of the disease
For example, the irrational use of antibiotics leads to serious bacterial drug resistance, the abuse of hormone drugs leads to systemic side effects and serious secondary infections, and the problem of fungal drug resistance is becoming more and more prominent
[0003] The treatment of fungal skin diseases requires fungal culture and strain identification before targeted drug therapy can be administered. However, the common problem now is that doctors administer medicines based on experience without identification, which can easily lead to drug resistance of the strains.
Canine mite dermatosis, especially scabies, can cause severe itching. The owner usually strongly requires antipruritic treatment, and doctors usually use glucocorticoid preparations as antipruritics, which will aggravate the condition and even cause secondary symptoms such as pyoderma sexual infection
For puppies under four months old, local Demodex usually heals naturally without treatment, but the owner often does not understand the treatment measures without administration, and will buy antipruritics by himself or refer to other hospitals. Antipruritics, which tend to trigger really serious skin conditions

Method used

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  • Traditional Chinese medicine liniment for treating dog and cat skin diseases and preparation method thereof
  • Traditional Chinese medicine liniment for treating dog and cat skin diseases and preparation method thereof
  • Traditional Chinese medicine liniment for treating dog and cat skin diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The preparation of embodiment 1 Chinese medicine ointment

[0041] 4 parts of white pomegranate, 2 parts of white fresh skin, 2 parts of berberine, and 2 parts of sophora, weigh the above drugs according to the proportion, a total of 100 grams, add 1000 ml of water to soak for 2 hours, decoct conventionally, and concentrate to the crude drug concentration of 1 g / ml, dispense at room temperature.

Embodiment 2

[0042] Embodiment 2 acute skin irritation test

[0043] The purpose of the experiment is to develop topical drugs for clinical application. First of all, it is necessary to ensure that the drugs will not cause damage to the skin and aggravate the disease. So do the acute skin irritation test first, if the acute test has damage to the skin, you need to add the chronic skin irritation test.

[0044] Experimental Materials

[0045] experimental animals

[0046] 10 Kunming mice of 18-22 g clean grade, half male and half male, were provided by Beijing Weitong Lihua Experimental Animal Co., Ltd., and the experiment was started after a week of feeding and observation to confirm the health. The mice were randomly divided into four groups, 1 normal group, 3 Huikangpining No. 1 group, 3 Huikangpining No. 2 group, and 3 Huikangpining No. 3 group.

[0047] Pharmaceutical reagents

[0048] Prepared compound Chinese medicine:

[0049] Huikang Pining No. 1: 4 parts of white pomegranate,...

Embodiment 3

[0067] Example 3 Antipruritic Pharmacodynamic Study of Chinese Medicine Prescriptions

[0068] Experimental Materials

[0069] Experimental animals and groups

[0070] Sixty clean-grade Kunming mice, half male and half male, were purchased from Beijing Weitong Lihua Company. Adaptive feeding for 5 days. Randomly divided into 5 groups.

[0071] Model group: only injected with 4-AP, without antipruritic drug treatment.

[0072] Positive control group: apply hydrocortisone ointment first, and then inject 4-AP.

[0073] Huikangpining No. 1 group: Apply Huikangpining No. 1 traditional Chinese medicine first, and then inject 4-AP.

[0074] Huikangpining No. 2 group: apply Huikangpining No. 2 traditional Chinese medicine first, and then inject 4-AP.

[0075] Huikangpining No. 3 group: apply Huikangpining No. 3 traditional Chinese medicine first, and then inject 4-AP.

[0076] Positive control group: hydrocortisone ointment

[0077] 4-aminopyridine (4-AP)

[0078] experimenta...

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Abstract

The invention provides a traditional Chinese medicine liniment for treating dog and cat skin diseases and a preparation method thereof. The traditional Chinese medicine liniment is prepared from the following raw materials in parts by weight: 4 parts of ampelopsis japonica, 2 parts of cortex dictamni, 2 parts of coptis chinensis and 2 parts of radix sophorae flavescentis. The compound traditionalChinese medicine liniment for external use is researched and developed and used for diagnosing and treating clinical skin diseases of pets. The liniment not only can effectively relieve pruritus symptoms of organisms, but also can treat skin injury symptoms such as skin ulcer according to symptoms, and strives for enough time for accurate and complete diagnosis of skin diseases by clinical first-line pet doctors.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine ointment for treating skin diseases of dogs and cats and a preparation method thereof. Background technique [0002] Bacterial, fungal and acarid are the most common pet skin diseases. However, skin diseases must be accurately diagnosed before treatment, and the current clinical treatment of skin diseases is generally rough and treated with empirical medication without diagnosis, resulting in serious drug abuse, resulting in delays or even deterioration of the disease. For example, the irrational use of antibiotics leads to serious bacterial drug resistance, the abuse of hormone drugs leads to systemic side effects and serious secondary infections, and the problem of fungal drug resistance is becoming more and more prominent. [0003] The treatment of fungal skin diseases requires fungal culture and strain identification bef...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61K9/08A61P17/00A61P31/02A61P31/04A61P33/14A61P17/02A61P17/04
CPCA61K9/0014A61K9/08A61K36/489A61K36/718A61K36/75A61K36/87A61K2236/331A61K2236/53A61P17/00A61P17/02A61P17/04A61P31/02A61P31/04A61P33/14A61K2300/00
Inventor 段慧琴杨佐君穆祥耿森段佳慧
Owner BEIJING UNIV OF AGRI
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