Traditional Chinese medicine liniment for treating dog and cat skin diseases and preparation method thereof
A smear and skin disease technology, which is applied in the field of traditional Chinese medicine smear for treating skin diseases of dogs and cats and its preparation, can solve the problems of exacerbation of disease, side effects, treatment of roughness, etc., and achieve the effect of alleviating itching symptoms
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Embodiment 1
[0040] The preparation of embodiment 1 Chinese medicine ointment
[0041] 4 parts of white pomegranate, 2 parts of white fresh skin, 2 parts of berberine, and 2 parts of sophora, weigh the above drugs according to the proportion, a total of 100 grams, add 1000 ml of water to soak for 2 hours, decoct conventionally, and concentrate to the crude drug concentration of 1 g / ml, dispense at room temperature.
Embodiment 2
[0042] Embodiment 2 acute skin irritation test
[0043] The purpose of the experiment is to develop topical drugs for clinical application. First of all, it is necessary to ensure that the drugs will not cause damage to the skin and aggravate the disease. So do the acute skin irritation test first, if the acute test has damage to the skin, you need to add the chronic skin irritation test.
[0044] Experimental Materials
[0045] experimental animals
[0046] 10 Kunming mice of 18-22 g clean grade, half male and half male, were provided by Beijing Weitong Lihua Experimental Animal Co., Ltd., and the experiment was started after a week of feeding and observation to confirm the health. The mice were randomly divided into four groups, 1 normal group, 3 Huikangpining No. 1 group, 3 Huikangpining No. 2 group, and 3 Huikangpining No. 3 group.
[0047] Pharmaceutical reagents
[0048] Prepared compound Chinese medicine:
[0049] Huikang Pining No. 1: 4 parts of white pomegranate,...
Embodiment 3
[0067] Example 3 Antipruritic Pharmacodynamic Study of Chinese Medicine Prescriptions
[0068] Experimental Materials
[0069] Experimental animals and groups
[0070] Sixty clean-grade Kunming mice, half male and half male, were purchased from Beijing Weitong Lihua Company. Adaptive feeding for 5 days. Randomly divided into 5 groups.
[0071] Model group: only injected with 4-AP, without antipruritic drug treatment.
[0072] Positive control group: apply hydrocortisone ointment first, and then inject 4-AP.
[0073] Huikangpining No. 1 group: Apply Huikangpining No. 1 traditional Chinese medicine first, and then inject 4-AP.
[0074] Huikangpining No. 2 group: apply Huikangpining No. 2 traditional Chinese medicine first, and then inject 4-AP.
[0075] Huikangpining No. 3 group: apply Huikangpining No. 3 traditional Chinese medicine first, and then inject 4-AP.
[0076] Positive control group: hydrocortisone ointment
[0077] 4-aminopyridine (4-AP)
[0078] experimenta...
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