Composition, preparation and application thereof comprising alcohol extract of Gongluomu and cordycepin
A technology of konol and composition, which is applied in the field of medicine and health care, can solve the problems of lack of lipid-lowering and weight-loss drugs and health products, etc., and achieve the effects of inhibiting the formation of lipid droplets, obvious efficacy and slimming efficacy.
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[0025] In the present invention, the mass ratio of the ethanol extract and cordycepin is preferably 1:1. In the present invention, the ethanol extract is preferably extracted with an aqueous ethanol solution with a volume fraction of 45% to 55%, more preferably obtained through extraction with an aqueous ethanol solution with a volume fraction of 50%. In the present invention, the preparation method of the alcoholic extract of the eucalyptus comprises the following steps: after mixing and soaking the eucalyptus and an aqueous ethanol solution, reflux extraction for 1-2 hours, collecting the extract, and drying to obtain the alcohol extract of the eucalyptus. In the present invention, the meritorious wood is preferably crushed before being mixed with the aqueous ethanol solution. The particle size of the meritorious wood after crushing is not particularly limited in the present invention, and conventional crushing is sufficient. In the present invention, the volume ratio of the...
Embodiment 1
[0034] The preparation method of Gongluo wood alcohol extract:
[0035] 1. Weigh 50g of gonglao wood, pulverize, sieve with 50 mesh, put it into a 500mL round bottom flask, add 10 times the volume of 50% (volume fraction) ethanol solution and soak at room temperature (25°C) for 2h.
[0036] 2. Place the round bottom flask in a heating mantle, heat to 100°C and reflux for 1.5h to collect the extract.
[0037] 3. Filter the extract with double layers of 200-mesh silk cloth, pour the filtrate into a rotary evaporator at 60°C, condense it into a paste by rotary evaporation, collect the concentrate, and store it in a refrigerator at 4°C.
[0038] 4. Pour the concentrated solution into a suitable container, carry out vacuum drying, 100°C, 1h, 80°C, 3h, the dry extract obtained is the alcohol extract of Gongluomu, weighing 2.12g, and the extraction rate is 4.24%.
[0039] The source of cordycepin: commercially available. The lipid-lowering and weight-reducing composition comprises ...
Embodiment 2
[0041] The preparation method of Gongluo wood alcohol extract:
[0042] 1. Weigh the gonglao wood, crush it, sieve it with 50 mesh, put it into a 500mL round bottom flask, add 10 times the volume of 50% (volume fraction) ethanol solution and soak it at room temperature (25°C) for 2h.
[0043] 2. Place the round bottom flask in a heating mantle, heat to 100°C and reflux for 1.5h to collect the extract.
[0044]3. Filter the extract with a double layer of 200-mesh silk cloth, pour the filtrate into a rotary evaporator, condense it into a paste by rotary evaporation at 60°C, collect the concentrate, and store it in a refrigerator at 4°C.
[0045] 4. Pour the concentrated solution into a suitable container, carry out vacuum drying, 100°C, 1h, 80°C, 3h, to obtain a dry extract, and collect the dry extract as the alcohol extract of Gongluomu.
[0046] The source of cordycepin: commercially available.
[0047] The lipid-lowering and weight-reducing composition comprises the alcohol...
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