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Compound bitter gourd peptide oral medicine for activating insulin and treating diabetes, and preparation method of compound bitter gourd peptide oral medicine

A technology of balsam pear peptide and insulin, which is applied to the preparation methods of peptides, chemical instruments and methods, pharmaceutical formulations, etc., can solve problems such as injury, normal islet function, injury and side effects, and achieve the effect of improving production efficiency and purity.

Pending Publication Date: 2020-02-07
李玉保 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, many diabetic patients take western medicine to reduce blood sugar rapidly in the early stage of the disease. However, western medicine will cause great harm and side effects to the body. This method not only fails to restore the function of islets of pancreas to normal, and the blood sugar drops steadily, but also makes the toxic and side effects of the drug accumulate in the body for a long time, resulting in greater damage.

Method used

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  • Compound bitter gourd peptide oral medicine for activating insulin and treating diabetes, and preparation method of compound bitter gourd peptide oral medicine
  • Compound bitter gourd peptide oral medicine for activating insulin and treating diabetes, and preparation method of compound bitter gourd peptide oral medicine
  • Compound bitter gourd peptide oral medicine for activating insulin and treating diabetes, and preparation method of compound bitter gourd peptide oral medicine

Examples

Experimental program
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Effect test

Embodiment 1

[0053] In parts by weight, the compound bitter melon peptide oral medicine for activating insulin and treating diabetes in this embodiment includes: 20 parts of bitter melon peptide powder, 4 parts of American ginseng, 10 parts of astragalus, 3 parts of ganoderma lucidum powder, 8 parts of yam powder, and 10 parts of wheat bran. 10 parts of guava leaf powder, 5 parts of onion extract, 5 parts of wolfberry, 12 parts of chrysanthemum notoginseng extract, 1 part of coix seed, 5 parts of konjac glucomannan, 8 parts of lotus leaf, oligomeric wood 5 parts sugar.

[0054] Further, the preparation method of the bitter melon peptide comprises the following steps:

[0055] S11. Take one or more of fresh balsam pear, dried balsam pear, and balsam pear seeds as balsam pear raw material, add deionized water 5 times the weight of balsam pear raw material, and soak at 25°C for 10-12h (preferably 10.5h), take out Then rinse with deionized water 2-3 times to remove pesticide residues and impu...

Embodiment 2

[0088] The only difference between this example and Example 1 is that, in parts by weight, the compound bitter melon peptide oral medicine for activating insulin and treating diabetes in this example consists of the following components: 30 parts of bitter melon peptide powder, 6 parts of American ginseng , 12 parts of astragalus, 5 parts of Ganoderma lucidum powder, 10 parts of yam powder, 15 parts of wheat bran, 12 parts of guava leaf powder, 10 parts of onion extract, 10 parts of wolfberry, 15 parts of chrysanthemum notoginseng extract, 2 coix seed 8 parts, 8 parts of konjac glucomannan, 10 parts of lotus leaf, 8 parts of xylooligosaccharide.

[0089]

[0090] The only difference between this example and Example 1 is that, in parts by weight, the compound bitter melon peptide oral medicine for activating insulin and treating diabetes in this example consists of the following components: 25 parts of bitter melon peptide powder, 5 parts of American ginseng , 11 parts of ast...

Embodiment 4

[0103] This embodiment also provides a preparation method of compound bitter gourd peptide oral medicine for activating insulin and treating diabetes, which includes:

[0104] S100. Prepare the bitter melon peptide powder and the chrysanthemum notoginseng extract respectively according to the preparation method of the balsam pear peptide powder and the chrysanthemum notoginseng extract described in one of embodiments 1-3;

[0105] S200. Weigh each component according to the dosage of the components in the compound bitter gourd peptide oral medicine described in one of the embodiments 1-3;

[0106]S300. Soak the American ginseng, astragalus, ganoderma powder, yam powder, wheat bran, guava leaf powder, onion extract, coix seed, lotus leaf, and wolfberry in water for 5-8 hours (preferably 6 hours), and use The weight of the soaked water is 5-8 times (preferably 7 times) of the total weight of American ginseng, astragalus, ganoderma powder, yam powder, wheat bran, guava leaf powde...

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Abstract

The invention discloses a compound bitter gourd peptide oral medicine for activating insulin and treating diabetes, and a preparation method of the compound bitter gourd peptide oral medicine. The compound bitter gourd peptide oral medicine is prepared from the components in parts by weight: 20-30 parts of bitter gourd peptide powder, 4-6 parts of American ginseng, 10-12 parts of radix astragali,3-5 parts of ganoderma lucidum powder, 8-10 parts of yam powder, 10-15 parts of wheat bran, 10-12 parts of guava leaf powder, 5-10 parts of an onion extract, 5-10 parts of fructus lycii, 12-15 parts of a gynura procumbens extract, 1-2 parts of coix seeds, 5-8 parts of konjac glucomannan, 8-10 parts of lotus leaves and 5-8 parts of xylo-oligosaccharide. According to the compound bitter gourd peptide oral medicine and the preparation method, the content of active components of bitter gourd peptide is increased through a special bitter gourd peptide extraction technology, and a better hypoglycemic effect is achieved through cooperative use of the active components of the bitter gourd peptide and other natural plant components.

Description

technical field [0001] The invention relates to the fields of drug development and biological fermentation. More specifically, the present invention relates to a compound bitter melon peptide oral medicine for activating insulin and treating diabetes and its preparation method. Background technique [0002] The incidence of diabetes in countries around the world is increasing year by year. According to the relevant data of the World Health Organization, there are more than 382 million diabetic patients in the world, and about 114 million diabetic patients in my country. [0003] Diabetes mellitus is a metabolic disease characterized by hyperglycemia, which is caused by defective insulin secretion or impaired biological action, or both, and can lead to various tissues, especially the eyes, kidneys, heart, blood vessels, nerves Chronic damage and dysfunction. The onset of hyperglycemia and diabetes has a variety of reasons, including congenital and acquired factors, but one...

Claims

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Application Information

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IPC IPC(8): A61K38/01A61P3/10A61P9/12A61P3/06A61P3/04C12P21/06C07K1/14C07K1/34A61K36/8994A61K31/736A61K31/702
CPCA61K38/01A61K36/258A61K36/481A61K36/074A61K36/8945A61K36/899A61K36/61A61K36/8962A61K36/815A61K36/28A61K36/8994A61K31/736A61K36/62A61K31/702A61P3/10A61P9/12A61P3/06A61P3/04C12P21/06C07K1/14C07K1/34A61K2236/19A61K2236/333A61K2236/39A61K2236/51A61K2236/331A61K2236/53A61K2300/00A61K38/10A61K38/011A61K36/185A61K36/88A61K9/145A61K9/0053A61K2236/17
Inventor 何静仁李玉保
Owner 李玉保
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